| Drug Name: | Amiloride (2609-46-3) |
|---|---|
| PubChem ID: | 16231 |
| SMILES: | C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N |
| InchiKey: | XSDQTOBWRPYKKA-UHFFFAOYSA-N |
| Therapeutic Category: |
| Molecular Weight (dalton) | : | 229.631 |
| LogP | : | -1.292 |
| Ring Count | : | 1 |
| Hydrogen Bond Acceptor Count | : | 5 |
| Hydrogen Bond Donor Count | : | 4 |
| Total Polar Surface Area | : | 159.29 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Quinidine (56-54-2) | Opposed Antiarrhythmic Activity Of Quinidine | Antagonistic | Not understood. The combination of quinidine and amiloride increased the QRS interval, but did not prolong the QT interval more than quinidine alone. | Amiloride-quinidine interaction: adverse outcomes |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
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This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category
| Toxicity | Source |
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