InAADR

Drug Information

Drug Name: Amiloride Hydrochloride (2016-88-8)
PubChem ID: 16230
SMILES: C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N.Cl
InchiKey: ACHKKGDWZVCSNH-UHFFFAOYSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 266.092
LogP: -0.8702
Ring Count: 1
Hydrogen Bond Acceptor Count: 5
Hydrogen Bond Donor Count: 4
Total Polar Surface Area: 159.29

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Distension ADReCS
Abdominal Infection MetaADEDB
Abdominal Pain ADReCS
Abdominal Tenderness MetaADEDB
Abnormal Gait MetaADEDB
Abscess Jaw MetaADEDB
Abscess Oral MetaADEDB
Accommodation Disorder MetaADEDB
Ache SIDER
Acid Reflux MetaADEDB
Acidosis MetaADEDB
Acidosis Renal Tubular MetaADEDB
Acute Glomerulonephritis MetaADEDB
Acute Kidney Injury MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Adenocarcinoma MetaADEDB
Adenopathy MetaADEDB
Adh Inappropriate MetaADEDB
Administration Site Pain MetaADEDB
Adynamic Ileus MetaADEDB
Afib MetaADEDB
Agitation ADReCS
Alkalosis MetaADEDB
Alkalosis Hypochloraemic MetaADEDB
Alopecia ADReCS
Alpha Haemolytic Streptococcal Infection MetaADEDB
Anaemia ADReCS
Anaemia Of Malignant Disease MetaADEDB
Anger MetaADEDB
Angina Pectoris ADReCS
Anorexia ADReCS
Antipsychotic Drug Level Increased MetaADEDB
Anxiety MetaADEDB
Aplastic Anaemia ADReCS
Appetite Disorder ADReCS
Application Site Erythema MetaADEDB
Application Site Pain MetaADEDB
Application Site Pruritus MetaADEDB
Aptyalism MetaADEDB
Arrhythmia ADReCS
Arrhythmia Supraventricular MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arteriospasm Coronary MetaADEDB
Arthralgia ADReCS
Arthritis MetaADEDB
Arthritis Infective MetaADEDB
Arthropathy MetaADEDB
Asthenia ADReCS
Asthmatic Crisis MetaADEDB
Asystole MetaADEDB
Atelectasis MetaADEDB
Atrial Tachycardia MetaADEDB
Atrioventricular Block ADReCS
Atrioventricular Block Complete ADReCS
Back Ache MetaADEDB
Back Pain ADReCS
Bacteraemia MetaADEDB
Bacterial Toxaemia MetaADEDB
Bence Jones Protein Urine MetaADEDB
Bile Duct Stone MetaADEDB
Biliary Dilatation MetaADEDB
Binocular Eye Movement Disorder MetaADEDB
Bladder Pain ADReCS
Bladder Spasm ADReCS
Bladder Tamponade MetaADEDB
Block Heart SIDER
Blood Albumin Decreased MetaADEDB
Blood Calcium Increased MetaADEDB
Blood Chloride Decreased MetaADEDB
Blood Creatinine Decreased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Culture Positive MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood In Urine MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Potassium Increased ADReCS
Blood Pressure Fluctuation MetaADEDB
Blood Sodium MetaADEDB
Blood Urea Increased MetaADEDB
Blood Uric Acid MetaADEDB
Bone Cancer Metastatic MetaADEDB
Bone Lesion MetaADEDB
Bone Marrow Failure MetaADEDB
Bone Marrow Oedema MetaADEDB
Bradycardia ADReCS
Bronchial Secretion Retention MetaADEDB
Bronchopneumonia MetaADEDB
Bruise MetaADEDB
Buttock Pain MetaADEDB
Cancer MetaADEDB
Cancer Pain MetaADEDB
Candida Infection MetaADEDB
Carcinoid Syndrome MetaADEDB
Carcinoid Tumour Of The Small Bowel MetaADEDB
Carcinoma Transitional Cell MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Failure Acute MetaADEDB
Cardiac Ischemia MetaADEDB
Cardiac Output Decreased MetaADEDB
Cardiac Tamponade MetaADEDB
Cataract MetaADEDB
Cauda Equina Syndrome MetaADEDB
Cellulitis MetaADEDB
Cerebral Infarct MetaADEDB
Chemotherapeutic Drug Level Increased MetaADEDB
Chest Infection MetaADEDB
Chest Pain ADReCS
Choking Sensation MetaADEDB
Cholangiolitis MetaADEDB
Chondrocalcinosis MetaADEDB
Chondromalacia MetaADEDB
Chronic Left Ventricular Failure MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Clostridium Difficile Toxin Test Positive MetaADEDB
Colitis MetaADEDB
Coma ADReCS
Confabulation MetaADEDB
Confusional State ADReCS
Constipation ADReCS
Contact Dermatitis MetaADEDB
Corona Virus Infection MetaADEDB
Coronary Artery Bypass MetaADEDB
Coronary Artery Stenosis MetaADEDB
Cough ADReCS
Cramp Muscle SIDER
Culture Positive MetaADEDB
Cutaneous Ulcer MetaADEDB
Cystitis Radiation MetaADEDB
Deafness Congenital MetaADEDB
Decreased Appetite ADReCS
Dehydration ADReCS
Demyelination MetaADEDB
Depressed Mood MetaADEDB
Depression ADReCS
Dermatitis ADReCS
Diabetes Insipidus MetaADEDB
Diabetes Insipidus Nephrogenic MetaADEDB
Diabetic Nephropathy MetaADEDB
Dialysis MetaADEDB
Diarrhoea ADReCS
Disease Progression MetaADEDB
Disseminated Lupus Erythematosus MetaADEDB
Disturbance In Sexual Arousal ADReCS
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Drowsiness MetaADEDB
Drug Dispensing Error MetaADEDB
Drug Effect Increased MetaADEDB
Drug Eruptions MetaADEDB
Drug Toxicity MetaADEDB
Dry Mouth ADReCS
Dyspepsia ADReCS
Dyspnoea ADReCS
Dysuria ADReCS
Ecg Signs Of Ventricular Hypertrophy MetaADEDB
Edema Extremities MetaADEDB
Effusion MetaADEDB
Ejection Fraction Decreased MetaADEDB
Electrocardiogram Change MetaADEDB
Electrocardiogram Qt Prolonged MetaADEDB
Electromechanical Dissociation MetaADEDB
Emesis MetaADEDB
Emotional Distress MetaADEDB
Emphysema MetaADEDB
Encephalitis Allergic MetaADEDB
Encephalopathy ADReCS
Enlarged Liver MetaADEDB
Enlarged Spleen MetaADEDB
Enterococcal Infection MetaADEDB
Enthesopathy MetaADEDB
Enuresis MetaADEDB
Eosinophilic Myocarditis MetaADEDB
Epistaxis MetaADEDB
Erectile Dysfunction ADReCS
Erosive Gastritis MetaADEDB
Erosive Oesophagitis MetaADEDB
Excess Potassium MetaADEDB
External Fixation Of Fracture MetaADEDB
Eye Inflammation MetaADEDB
Fascitis Plantar MetaADEDB
Fatigability SIDER
Fatigue ADReCS
Febrile Neutropenia MetaADEDB
Feeling Abnormal ADReCS
Flatulence ADReCS
Fluid Overload MetaADEDB
Foetor Hepaticus ADReCS
Foot Deformity MetaADEDB
Foot Fracture MetaADEDB
Fullness Abdominal SIDER
Fungal Disease MetaADEDB
Gas SIDER
Gas Pain SIDER
Gastroduodenal Ulcer MetaADEDB
Gastroenteritis MetaADEDB
Gastrointestinal Bleed MetaADEDB
Gastrointestinal Disturbance ADReCS
Gastrointestinal Haemorrhage ADReCS
Gastrointestinal Pain ADReCS
General Physical Health Deterioration MetaADEDB
Glomerular Filtration Rate Decreased MetaADEDB
Glucose Urine MetaADEDB
Granuloma MetaADEDB
Growth Disorders MetaADEDB
Gynaecomastia ADReCS
Haemangioma MetaADEDB
Haematemesis MetaADEDB
Haematoma MetaADEDB
Haemodynamic Instability MetaADEDB
Haemoglobin ADReCS
Haemorrhage ADReCS
Haemorrhage Subcutaneous MetaADEDB
Haemorrhagic Disorder MetaADEDB
Hallucination Tactile MetaADEDB
Hand Deformity MetaADEDB
Headache ADReCS
Heart Failure MetaADEDB
Heartburn ADReCS
Hepatic Encephalopathy ADReCS
Hepatic Function Abnormal ADReCS
Hepatic Lesion MetaADEDB
Hepatocellular Damage MetaADEDB
Hepatocellular Injury ADReCS
Hepatotoxicity MetaADEDB
Hernial Eventration MetaADEDB
Herpes Simplex MetaADEDB
Herpes Virus Infection MetaADEDB
Histoplasmosis Disseminated MetaADEDB
Hyperammonaemia MetaADEDB
Hyperbaric Oxygen Therapy MetaADEDB
Hyperchloraemia MetaADEDB
Hyperhidrosis MetaADEDB
Hyperkalemia MetaADEDB
Hyperkinesia ADReCS
Hypertension MetaADEDB
Hypoalbuminaemia MetaADEDB
Hypokalaemia MetaADEDB
Hypokalemia MetaADEDB
Hypokalemic Periodic Paralysis MetaADEDB
Hypomagnesaemia MetaADEDB
Hypomagnesemia 2 Renal MetaADEDB
Hyponatraemia ADReCS
Hyponatremia MetaADEDB
Hypophosphataemia MetaADEDB
Hypotension ADReCS
Hypotension Orthostatic MetaADEDB
Hypothyroid MetaADEDB
Hypovolaemic Shock MetaADEDB
Immune Reconstitution Syndrome MetaADEDB
Impotence ADReCS
Inappropriate Schedule Of Drug Administration MetaADEDB
Infection MetaADEDB
Infection Upper Respiratory MetaADEDB
Infection Urinary Tract MetaADEDB
Infection Viral MetaADEDB
Inflammation MetaADEDB
Infusion Site Mobility Decreased MetaADEDB
Injection Site Dermatitis MetaADEDB
Insomnia ADReCS
Internal Fixation Of Fracture MetaADEDB
International Normalised Ratio Increased MetaADEDB
Intestinal Resection MetaADEDB
Intraocular Pressure Increased ADReCS
Investigation Abnormal MetaADEDB
Itch MetaADEDB
Jaundice ADReCS
Kidney Pain MetaADEDB
Kidney Transplant MetaADEDB
Laceration MetaADEDB
Lacunar Infarction MetaADEDB
Left Ventricular Dysfunction MetaADEDB
Left Ventricular Hypertrophy MetaADEDB
Leucopenia MetaADEDB
Leukopenia Neonatal MetaADEDB
Libido Decreased ADReCS
Lichenoid Keratosis MetaADEDB
Liddle Syndrome MetaADEDB
Liver Disorder ADReCS
Lung Consolidation MetaADEDB
Lung Diseases Obstructive MetaADEDB
Lymphangiosis Carcinomatosa MetaADEDB
Lymphocyte Morphology Abnormal MetaADEDB
Lymphoma MetaADEDB
Malabsorption MetaADEDB
Malignant Neoplasm Progression MetaADEDB
Malignant Splenic Neoplasm MetaADEDB
Malnourished MetaADEDB
Meningioma MetaADEDB
Mental Status Changes MetaADEDB
Metastases To Liver MetaADEDB
Metastases To Lymph Nodes MetaADEDB
Metastases To Spine MetaADEDB
Metastases To Thorax MetaADEDB
Metastatic Carcinoid Tumour MetaADEDB
Monocyte Percentage Decreased MetaADEDB
Mucosal Inflammation MetaADEDB
Multi-Organ Failure MetaADEDB
Muscle Fatigue MetaADEDB
Muscle Spasms ADReCS
Muscular Weakness ADReCS
Musculoskeletal Discomfort ADReCS
Myelodysplasia MetaADEDB
Nasal Congestion ADReCS
Nasal Disorder MetaADEDB
Nausea ADReCS
Neck Pain ADReCS
Neoplasm Invasiveness MetaADEDB
Nervousness ADReCS
Neuroendocrine Tumour MetaADEDB
Neurological Infection MetaADEDB
Neutropenia ADReCS
Neutropenic Colitis MetaADEDB
Neutropenic Infection MetaADEDB
Neutropenic Sepsis MetaADEDB
No Therapeutic Response MetaADEDB
Non-Cardiac Chest Pain MetaADEDB
Opportunistic Infection MetaADEDB
Oral Herpes MetaADEDB
Oral Pruritus ADReCS
Orthostatic Hypotension ADReCS
Osteopenia MetaADEDB
Osteoporosis MetaADEDB
Osteosclerosis MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Pain ADReCS
Pain In Extremity ADReCS
Palpitation MetaADEDB
Palpitations ADReCS
Paraesthesia ADReCS
Paralysis ADReCS
Paralysis Flaccid ADReCS
Peptic Ulcer ADReCS
Pericardial Effusion MetaADEDB
Peripheral Sensorimotor Neuropathy MetaADEDB
Peripheral Sensory Neuropathy MetaADEDB
Peritoneal Dialysis Complication MetaADEDB
Peritonitis Bacterial MetaADEDB
Petechia MetaADEDB
Physical Disability MetaADEDB
Platelet Count MetaADEDB
Pleural Effusion MetaADEDB
Pneumonia Fungal MetaADEDB
Po2 MetaADEDB
Pollakiuria ADReCS
Polyuria ADReCS
Post Procedural Pain MetaADEDB
Pruritus ADReCS
Pulmonary Hypertension MetaADEDB
Pulmonary Toxicity MetaADEDB
Pustular Psoriasis MetaADEDB
Pyelonephritis MetaADEDB
Rales MetaADEDB
Rash ADReCS
Renal Cancer Stage I MetaADEDB
Renal Insufficiency MetaADEDB
Reperfusion Injury MetaADEDB
Respiratory Failure MetaADEDB
Rheumatoid Nodule MetaADEDB
Right Heart Failure MetaADEDB
Rotator Cuff Repair MetaADEDB
Scar MetaADEDB
Scoliosis MetaADEDB
Seizures MetaADEDB
Sensory Disturbance MetaADEDB
Serum Potassium Increased SIDER
Shock ADReCS
Shoulder Pain ADReCS
Sinusitis MetaADEDB
Small Intestinal Obstruction MetaADEDB
Smoker MetaADEDB
Somnolence ADReCS
Speech Disorder MetaADEDB
Spinal Laminectomy MetaADEDB
Splenic Cyst MetaADEDB
Status Epilepticus MetaADEDB
Stress Fracture MetaADEDB
Subileus MetaADEDB
Superficial Thrombophlebitis MetaADEDB
Superior Vena Cava Syndrome MetaADEDB
Syncope Vasovagal MetaADEDB
Synovial Cyst MetaADEDB
Tachycardia Ventricular MetaADEDB
Tendon Disorder MetaADEDB
Tension ADReCS
Therapy Non-Responder MetaADEDB
Thirst ADReCS
Tibia Fracture MetaADEDB
Tinnitus ADReCS
Tooth Fracture MetaADEDB
Transaminases Increased MetaADEDB
Tremor ADReCS
Tumour Lysis Syndrome MetaADEDB
Ulcer ADReCS
Urethral Obstruction MetaADEDB
Urine Ketone Body Present MetaADEDB
Urine Output Increased ADReCS
Urticaria MetaADEDB
Vascular Graft Occlusion MetaADEDB
Vasoconstriction MetaADEDB
Vasospasm MetaADEDB
Vein Disorder MetaADEDB
Venous Occlusion MetaADEDB
Vertigo ADReCS
Viral Pharyngitis MetaADEDB
Visual Disturbance ADReCS
Visual Impairment ADReCS
Vomiting ADReCS
Weakness SIDER
Wound Infection MetaADEDB
Wrong Drug Administered MetaADEDB

InAADR: Drug-Protein-ADRs database