InAADR

Drug Information

Drug Name: Tiotropium (186691-13-4)
PubChem ID: 5487427
SMILES: C[N+]1([C@@H]2CC(C[C@H]1[C@H]3[C@@H]2O3)OC(=O)C(C4=CC=CS4)(C5=CC=CS5)O)C
InchiKey: LERNTVKEWCAPOY-FPISHFTHSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 392.522
LogP: 2.3457
Ring Count: 2
Hydrogen Bond Acceptor Count: 6
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 59.06

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort MetaADEDB
Abdominal Infection MetaADEDB
Abdominal Pain ADReCS
Abnormal Dreams MetaADEDB
Abnormal Lfts MetaADEDB
Abnormal Movements MetaADEDB
Abnormal Vision MetaADEDB
Abscess Bacterial MetaADEDB
Aching Joints MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Respiratory Failure MetaADEDB
Adrenal Insufficiency MetaADEDB
Adynamic Ileus MetaADEDB
Afib MetaADEDB
Allergic Alveolitis MetaADEDB
Allergic Dermatitis MetaADEDB
Allergic Granulomatous Angiitis MetaADEDB
Allergic Reaction ADReCS
Allergies MetaADEDB
Anemia Aplastic MetaADEDB
Aneurysm MetaADEDB
Angina Pectoris ADReCS
Angioedema ADReCS
Anosmia MetaADEDB
Anti-Ss-A Antibody Positive MetaADEDB
Antimicrobial Susceptibility Test Resistant MetaADEDB
Aortic Aneurysm MetaADEDB
Aortic Valve Disease Mixed MetaADEDB
Aortic Valve Replacement MetaADEDB
Apathy MetaADEDB
Aphonia MetaADEDB
Apparent Death MetaADEDB
Aptyalism MetaADEDB
Arteriosclerosis Obliterans MetaADEDB
Arthralgia ADReCS
Arthritis ADReCS
Arthritis Rheumatoid MetaADEDB
Asthma MetaADEDB
Atelectasis MetaADEDB
Atrial Fibrillation ADReCS
Attention Deficit/Hyperactivity Disorder MetaADEDB
Aura MetaADEDB
Back Ache MetaADEDB
Bacterial Toxaemia MetaADEDB
Benign Prostatic Hyperplasia ADReCS
Bile Duct Stone MetaADEDB
Biopsy Bladder Abnormal MetaADEDB
Birth Defect MetaADEDB
Bladder Disorder MetaADEDB
Bladder Neck Obstruction ADReCS
Bladder Retention MetaADEDB
Blepharoptosis MetaADEDB
Blood Amylase Decreased MetaADEDB
Blood Calcium MetaADEDB
Blood Chloride Decreased MetaADEDB
Blood Cholesterol MetaADEDB
Blood Creatinine Decreased MetaADEDB
Blood Insulin MetaADEDB
Blood Magnesium Decreased MetaADEDB
Blood Phosphorus Decreased MetaADEDB
Blood Phosphorus Increased MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Pressure Fluctuation MetaADEDB
Blood Sodium MetaADEDB
Blood Urea Decreased MetaADEDB
Blurred Vision MetaADEDB
Bone Cancer Metastatic MetaADEDB
Bone Debridement MetaADEDB
Bone Density Decreased MetaADEDB
Bone Disorder MetaADEDB
Bone Erosion MetaADEDB
Bone Fracture MetaADEDB
Bone Marrow Disorder MetaADEDB
Bone Pain ADReCS
Brain Concussion MetaADEDB
Brain Natriuretic Peptide Increased MetaADEDB
Brain Oedema MetaADEDB
Breast Prosthesis Implantation MetaADEDB
Bronchitis MetaADEDB
Bronchospasm Paradoxical ADReCS
Bronchostenosis MetaADEDB
Bulging MetaADEDB
Bunion MetaADEDB
C-Reactive Protein Increased MetaADEDB
Candida Infection MetaADEDB
Candida Sepsis MetaADEDB
Candidiasis ADReCS
Candidiasis Of Mouth MetaADEDB
Carcinoma Of The Cervix MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Failure MetaADEDB
Cardiac Fibrillation ADReCS
Cardioactive Drug Level MetaADEDB
Cardiomyopathy MetaADEDB
Carotid Artery Stent Insertion MetaADEDB
Cartilage Development Disorder MetaADEDB
Cataract ADReCS
Catheter Placement MetaADEDB
Catheter Removal MetaADEDB
Central Nervous System Infection MetaADEDB
Cervical Dysplasia MetaADEDB
Cervicalgia MetaADEDB
Chest Pain ADReCS
Chest X-Ray Abnormal MetaADEDB
Choking Sensation MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Clostridium Difficile Colitis MetaADEDB
Colitis MetaADEDB
Colon Polypectomy MetaADEDB
Congenital Mitral Valve Incompetence MetaADEDB
Congenital Oesophageal Anomaly MetaADEDB
Constipated MetaADEDB
Constipation ADReCS
Contact Dermatitis MetaADEDB
Continuous Positive Airway Pressure MetaADEDB
Contracture MetaADEDB
Coronary Artery Bypass MetaADEDB
Cough ADReCS
Coughing Blood MetaADEDB
Crackles Lung MetaADEDB
Cranial Nerve Disorder MetaADEDB
Cyst MetaADEDB
Deafness Neurosensory MetaADEDB
Deafness Unilateral MetaADEDB
Death MetaADEDB
Decreased Interest MetaADEDB
Defaecation Urgency MetaADEDB
Deglutition Disorder MetaADEDB
Dental Care MetaADEDB
Dental Discomfort MetaADEDB
Dental Pain MetaADEDB
Depression ADReCS
Dermatitis ADReCS
Dermographism MetaADEDB
Device Interaction MetaADEDB
Difficulty In Micturition MetaADEDB
Diplopia MetaADEDB
Disorder Lung MetaADEDB
Diverticulum MetaADEDB
Dizziness ADReCS
Drop Attacks MetaADEDB
Drug Ineffective MetaADEDB
Dry Eye MetaADEDB
Dry Mouth ADReCS
Dry Throat MetaADEDB
Dysgeusia MetaADEDB
Dyspepsia ADReCS
Dysphagia ADReCS
Dysphemia MetaADEDB
Dysphonia ADReCS
Dystonia MetaADEDB
Dysuria ADReCS
Easy Bruisability MetaADEDB
Effusion MetaADEDB
Elderly ADReCS
Elevated Prostate Specific Antigen MetaADEDB
Emotional Distress MetaADEDB
Emphysema MetaADEDB
Empyema MetaADEDB
Encephalopathy MetaADEDB
End Stage Aids MetaADEDB
Endocrine Neoplasm Malignant MetaADEDB
Enzyme Abnormality MetaADEDB
Epistaxis ADReCS
Erosive Oesophagitis MetaADEDB
Erythema Migrans MetaADEDB
Erythema Nodosum MetaADEDB
Escherichia Urinary Tract Infection MetaADEDB
Excessive Granulation Tissue MetaADEDB
Extremity Pain MetaADEDB
Eye Pain MetaADEDB
Fasciitis MetaADEDB
Fatigue MetaADEDB
Febrile Neutropenia MetaADEDB
Feeling Of Despair MetaADEDB
Feelings Of Worthlessness MetaADEDB
Female Sterilisation MetaADEDB
Fibrin D Dimer MetaADEDB
Fluid Overload MetaADEDB
Foaming At Mouth MetaADEDB
Food Intolerance MetaADEDB
Fractured Sacrum MetaADEDB
Fungal Disease MetaADEDB
Gall Bladder MetaADEDB
Gastrointestinal Disorder ADReCS
Gastrointestinal Pain ADReCS
Gastrooesophageal Reflux Disease ADReCS
General Physical Health Deterioration MetaADEDB
Giardiasis MetaADEDB
Glaucoma ADReCS
Glossitis ADReCS
Gout MetaADEDB
Granulocytosis MetaADEDB
Granuloma MetaADEDB
Haematotoxicity MetaADEDB
Haemorrhagic Hepatic Cyst MetaADEDB
Headache ADReCS
Hearing Aid User MetaADEDB
Heart Rate Abnormal MetaADEDB
Heart Rate Increased MetaADEDB
Hemiplegia MetaADEDB
Hepatic Enzyme MetaADEDB
Hepatic Neoplasm Malignant MetaADEDB
Hepatic Trauma MetaADEDB
Hernia Hiatal MetaADEDB
Herpes Nos MetaADEDB
Herpes Virus Infection ADReCS
Herpes Zoster ADReCS
High Density Lipoprotein Decreased MetaADEDB
Hordeolum MetaADEDB
Hot Flash MetaADEDB
Human Papilloma Virus Test Positive MetaADEDB
Hyperbaric Oxygen Therapy MetaADEDB
Hypercholesterolaemia ADReCS
Hyperglycaemia ADReCS
Hypermetropia MetaADEDB
Hypersensitivity ADReCS
Hypertonia MetaADEDB
Hypertrophy ADReCS
Hypoaesthesia MetaADEDB
Hypoglycaemia Neonatal MetaADEDB
Hypophagia MetaADEDB
Hyporeflexia MetaADEDB
Hypoxia MetaADEDB
Ild MetaADEDB
Ileus Paralytic ADReCS
Immunoglobulins Decreased MetaADEDB
Implant Site Infection MetaADEDB
Impulsive Behaviour MetaADEDB
Incisional Drainage MetaADEDB
Incorrect Route Of Drug Administration MetaADEDB
Increased Upper Airway Secretion MetaADEDB
Infection ADReCS
Infection Urinary Tract MetaADEDB
Infective Exacerbation Of Chronic Obstructive Airways Disease MetaADEDB
Influenza ADReCS
Influenza Like Illness ADReCS
Injection Site Calcification MetaADEDB
Insomnia ADReCS
Intervertebral Disc Degeneration MetaADEDB
Intervertebral Disc Disorder MetaADEDB
Intervertebral Disc Herniation MetaADEDB
Intestinal Functional Disorder MetaADEDB
Intraocular Pressure Increased ADReCS
Ischaemic Hepatitis MetaADEDB
Jaw Disorder MetaADEDB
Jaw Operation MetaADEDB
Joint Effusion MetaADEDB
Joint Injury MetaADEDB
Kidney Infection MetaADEDB
Kidney Pain MetaADEDB
Laryngitis ADReCS
Laryngospasm MetaADEDB
Leg Pain ADReCS
Lethargy MetaADEDB
Leukopenia Neonatal MetaADEDB
Life Expectancy Shortened MetaADEDB
Life Support MetaADEDB
Lipase MetaADEDB
Lipids Abnormal MetaADEDB
Local Swelling MetaADEDB
Loop Electrosurgical Excision Procedure MetaADEDB
Loose Tooth MetaADEDB
Lung Fibrosis MetaADEDB
Lung Infiltration MetaADEDB
Lung Neoplasm MetaADEDB
Lung Neoplasm Malignant MetaADEDB
Malignant Melanoma MetaADEDB
Mastication Disorder MetaADEDB
Mechanical Ventilation MetaADEDB
Medical Device Complication MetaADEDB
Medical Device Removal MetaADEDB
Mental Disorder MetaADEDB
Mesenteric Vascular Insufficiency MetaADEDB
Metabolic Function Test MetaADEDB
Micturition Urgency MetaADEDB
Mitochondrial Myopathy MetaADEDB
Mouth Ulceration ADReCS
Mucosal Dryness MetaADEDB
Muscle Disorder MetaADEDB
Muscle Hypertrophy MetaADEDB
Muscle Weakness MetaADEDB
Musculoskeletal Discomfort ADReCS
Musculoskeletal Disorder MetaADEDB
Musculoskeletal Pain MetaADEDB
Myalgia ADReCS
Mycobacterium Avium Complex Infection MetaADEDB
Myelocyte Count Decreased MetaADEDB
Nasal Dryness MetaADEDB
Neumonia MetaADEDB
Neuropathy Peripheral MetaADEDB
Nocturia MetaADEDB
Nodule MetaADEDB
Obstruction ADReCS
Oedema ADReCS
Oesophagogastric Fundoplasty MetaADEDB
Oral Candidiasis ADReCS
Oral Surgery MetaADEDB
Oropharyngeal Pain ADReCS
Osteitis Deformans MetaADEDB
Osteoarthritis MetaADEDB
Osteoporosis MetaADEDB
Osteotomy MetaADEDB
Oxygen Consumption Increased MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Pain ADReCS
Pain In Extremity ADReCS
Pain In Throat MetaADEDB
Palpitations ADReCS
Pancreatitis Chronic MetaADEDB
Paraesthesia ADReCS
Pelvic Fluid Collection MetaADEDB
Pharyngeal Disorder MetaADEDB
Pharyngitis ADReCS
Physical Disability MetaADEDB
Pinguecula MetaADEDB
Pleural Effusion MetaADEDB
Pleural Fibrosis MetaADEDB
Polyneuropathy MetaADEDB
Polyp MetaADEDB
Postmenopausal Bleeding MetaADEDB
Postoperative Wound Complication MetaADEDB
Primary Sequestrum MetaADEDB
Proctalgia MetaADEDB
Prostate Cancer Recurrent MetaADEDB
Prostatic Obstruction MetaADEDB
Pruritus ADReCS
Pseudomonas Bronchitis MetaADEDB
Pulmonary Congestion MetaADEDB
Pulmonary Radiation Injury MetaADEDB
Radiation Associated Pain MetaADEDB
Radiation Oesophagitis MetaADEDB
Radical Hysterectomy MetaADEDB
Radicular Syndrome MetaADEDB
Radiculitis Lumbosacral MetaADEDB
Radiotherapy MetaADEDB
Rash ADReCS
Reflux Esophagitis MetaADEDB
Respiratory Failure MetaADEDB
Respiratory Therapy MetaADEDB
Respiratory Tract Infection ADReCS
Rhinitis ADReCS
Rhonchi MetaADEDB
Risus Sardonicus MetaADEDB
Salivary Gland Enlargement MetaADEDB
Scar MetaADEDB
Secretion Discharge MetaADEDB
Self-Injurious Ideation MetaADEDB
Shoulder Operation MetaADEDB
Sinus Disorder MetaADEDB
Sinusitis ADReCS
Sleep Apnea MetaADEDB
Sleep Disorder Due To General Medical Condition Insomnia Type MetaADEDB
Spinal Column Stenosis MetaADEDB
Spinal Decompression MetaADEDB
Spinal Nerve Stimulator Implantation MetaADEDB
Spinal Osteoarthritis MetaADEDB
Sputum Discoloured MetaADEDB
Stomatitis ADReCS
Supraventricular Tachycardia ADReCS
Surgery MetaADEDB
Swollen Tongue MetaADEDB
Tachycardia ADReCS
Telangiectases MetaADEDB
Tendon Disorder MetaADEDB
Therapeutic Response Decreased MetaADEDB
Throat Irritation ADReCS
Thyroid Neoplasia MetaADEDB
Tongue Disorder MetaADEDB
Tongue Exfoliation MetaADEDB
Tooth Extraction MetaADEDB
Tooth Infection MetaADEDB
Transurethral Prostatectomy MetaADEDB
Type I Hypersensitivity ADReCS
Ulcer ADReCS
Ulcerative Stomatitis MetaADEDB
Upper Respiratory Tract Infection ADReCS
Urethral Stenosis MetaADEDB
Urinary Retention ADReCS
Urinary Tract Disorder MetaADEDB
Urinary Tract Infection ADReCS
Urticaria ADReCS
Varicose Vein Ruptured MetaADEDB
Vascular Skin Disorder MetaADEDB
Ventricular Hypokinesia MetaADEDB
Viith Nerve Paralysis MetaADEDB
Violence-Related Symptom MetaADEDB
Vision Blurred ADReCS
Vomiting ADReCS
Walking Aid User MetaADEDB
Weight Gain MetaADEDB
Wheeze MetaADEDB

InAADR: Drug-Protein-ADRs database