InAADR

Drug Information

Drug Name: Fosaprepitant (172673-20-0)
PubChem ID: 219090
SMILES: C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O[C@@H]2[C@@H](N(CCO2)CC3=NC(=O)N(N3)P(=O)(O)O)C4=CC=C(C=C4)F
InchiKey: BARDROPHSZEBKC-OITMNORJSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 614.411
LogP: 4.3663
Ring Count: 3
Hydrogen Bond Acceptor Count: 7
Hydrogen Bond Donor Count: 3
Total Polar Surface Area: 129.91

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort PROTECT
Abdominal Distension ADReCS
Abdominal Pain ADReCS
Abdominal Pain ADReCS
Acne ADReCS
Alanine Aminotransferase Increased ADReCS
Anaemia ADReCS
Anaphylactic Reaction ADReCS
Anxiety ADReCS
Aspartate Aminotransferase Increased ADReCS
Asthenia ADReCS
Blood Alkaline Phosphatase Increased ADReCS
Blood Pressure Increased ADReCS
Blood Sodium Decreased PROTECT
Bradycardia ADReCS
Candida Infection PROTECT
Candidiasis ADReCS
Cardiovascular Disorder ADReCS
Chest Discomfort ADReCS
Chills ADReCS
Cognitive Disorder ADReCS
Conjunctivitis ADReCS
Constipation ADReCS
Cough ADReCS
Decreased Appetite ADReCS
Diarrhoea ADReCS
Disorientation ADReCS
Dizziness ADReCS
Dreaming Abnormal ADReCS
Dry Mouth ADReCS
Duodenal Ulcer ADReCS
Duodenal Ulcer Perforation PROTECT
Dysarthria ADReCS
Dysgeusia ADReCS
Dyspepsia ADReCS
Dyspnoea ADReCS
Dysuria ADReCS
Epigastric Discomfort ADReCS
Eructation ADReCS
Erythema ADReCS
Euphoric Mood ADReCS
Faeces Hard ADReCS
Fatigue ADReCS
Febrile Neutropenia ADReCS
Flatulence ADReCS
Flushing ADReCS
Gait Disturbance ADReCS
Gastrointestinal Sounds Abnormal ADReCS
Gastrooesophageal Reflux Disease ADReCS
Glucose Urine Present PROTECT
Haematuria ADReCS
Headache ADReCS
Hiccups ADReCS
Hot Flush ADReCS
Hyperglycaemia ADReCS
Hyperhidrosis ADReCS
Hypersensitivity PROTECT
Hypoaesthesia PROTECT
Hyponatraemia ADReCS
Infection ADReCS
Infusion Site Erythema ADReCS
Infusion Site Induration ADReCS
Infusion Site Pain ADReCS
Infusion Site Pruritus ADReCS
Infusion Site Thrombosis PROTECT
Insomnia ADReCS
Lethargy ADReCS
Malaise ADReCS
Miosis ADReCS
Muscle Spasms ADReCS
Muscular Weakness ADReCS
Myalgia ADReCS
Nausea ADReCS
Neutropenic Colitis ADReCS
Neutrophil Count Decreased ADReCS
Oedema ADReCS
Oropharyngeal Pain PROTECT
Palpitations ADReCS
Paraesthesia ADReCS
Pharyngitis ADReCS
Photosensitivity Reaction ADReCS
Pollakiuria ADReCS
Polydipsia ADReCS
Polyuria ADReCS
Postnasal Drip ADReCS
Pruritus ADReCS
Rash ADReCS
Rash Pruritic PROTECT
Red Blood Cells Urine Positive PROTECT
Seborrhoea ADReCS
Sensory Disturbance ADReCS
Skin Lesion ADReCS
Sneezing ADReCS
Somnolence ADReCS
Staphylococcal Infection ADReCS
Stevens-Johnson Syndrome ADReCS
Stomach Discomfort ADReCS
Stomatitis ADReCS
Subileus PROTECT
Thirst ADReCS
Throat Irritation ADReCS
Thrombophlebitis ADReCS
Tinnitus ADReCS
Toxic Epidermal Necrolysis PROTECT
Upper-Airway Cough Syndrome PROTECT
Urine Output Increased PROTECT
Urticaria ADReCS
Visual Acuity Reduced ADReCS
Vomiting ADReCS
Weight Decreased ADReCS
Weight Increased ADReCS
Wheezing ADReCS

InAADR: Drug-Protein-ADRs database