InAADR

Drug Information

Drug Name: Combivir (165456-81-5)
PubChem ID: 160352
SMILES: CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)N=[N+]=[N-].C1[C@H](O[C@H](S1)CO)N2C=CC(=NC2=O)N
InchiKey: LHCOVOKZWQYODM-CPEOKENHSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 496.506
LogP: -0.79038
Ring Count: 2
Hydrogen Bond Acceptor Count: 13
Hydrogen Bond Donor Count: 4
Total Polar Surface Area: 223.45

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
17-Hydroxyprogesterone Increased MetaADEDB
Abdominal Distension MetaADEDB
Abdominal Hernia MetaADEDB
Abdominal Hernia MetaADEDB
Abdominal Pain MetaADEDB
Abdominal Pain MetaADEDB
Abnormal Laboratory Findings MetaADEDB
Abnormal Loss Of Weight MetaADEDB
Abortion MetaADEDB
Abortion Induced MetaADEDB
Abortion Missed MetaADEDB
Accessory Auricle MetaADEDB
Accident MetaADEDB
Aching Joints MetaADEDB
Acoustic Stimulation Tests Abnormal MetaADEDB
Acquired Protein S Deficiency MetaADEDB
Acrochordon MetaADEDB
Acute Fatty Liver Of Pregnancy MetaADEDB
Acute Myeloblastic Leukemia MetaADEDB
Acute Otitis Media MetaADEDB
Acute Respiratory Failure MetaADEDB
Adhesion MetaADEDB
Adrenal Cyst MetaADEDB
Adrenogenital Syndrome MetaADEDB
Akinesia MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Albumin Urine Present MetaADEDB
Alcohol Detoxification MetaADEDB
Alcohol Interaction MetaADEDB
Alcohol Problem MetaADEDB
Allergic Dermatitis MetaADEDB
Allergic Rhinitis MetaADEDB
Allergic Vasculitis MetaADEDB
Alpha 1 Foetoprotein MetaADEDB
Alpha 1 Foetoprotein Increased MetaADEDB
Alveolitis MetaADEDB
Ammonia Increased MetaADEDB
Amniocentesis Abnormal MetaADEDB
Amniorrhexis MetaADEDB
Amniotic Band Syndrome MetaADEDB
Amniotic Cavity Disorder MetaADEDB
Anaemia MetaADEDB
Anaemia Of Pregnancy MetaADEDB
Anaesthesia MetaADEDB
Anal Pruritus MetaADEDB
Anal Stenosis MetaADEDB
Anemia Aplastic MetaADEDB
Anencephaly MetaADEDB
Aneurysm MetaADEDB
Angina Unstable MetaADEDB
Angiopathy MetaADEDB
Anotia MetaADEDB
Anoxia MetaADEDB
Antepartum Haemorrhage MetaADEDB
Anti-Hbs Antibody Positive MetaADEDB
Anticholinergic Syndrome MetaADEDB
Aorta Hypoplasia MetaADEDB
Apgar Score Low MetaADEDB
Aphagia MetaADEDB
Aplasia Cutis Congenita MetaADEDB
Aplasia Pure Red Cell MetaADEDB
Application Site Rash MetaADEDB
Arnold-Chiari Malformation MetaADEDB
Arterial Stent Insertion MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Arteriovenous Malformation MetaADEDB
Ascites MetaADEDB
Asthenia MetaADEDB
Atherosclerosis MetaADEDB
Atrial Septal Defect MetaADEDB
Atrioventricular Canal MetaADEDB
Atrioventricular Septal Defect MetaADEDB
Bacterial Sepsis MetaADEDB
Bacterial Toxaemia MetaADEDB
Bacterial Vaginitis MetaADEDB
Beta Haemolytic Streptococcal Infection MetaADEDB
Bile Duct Stone MetaADEDB
Biliary Fibrosis MetaADEDB
Biliary Tract Infection MetaADEDB
Biopsy Bile Duct Abnormal MetaADEDB
Biopsy Bone Marrow Abnormal MetaADEDB
Biopsy Liver Abnormal MetaADEDB
Birth Defect MetaADEDB
Birth Trauma MetaADEDB
Bladder Distension MetaADEDB
Bladder Hypertrophy MetaADEDB
Blood Alcohol Increased MetaADEDB
Blood Amino Acid Level Increased MetaADEDB
Blood Amylase Increased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Blister MetaADEDB
Blood Cortisol Increased MetaADEDB
Blood Count Abnormal MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Creatine Phosphokinase Mb Increased MetaADEDB
Blood Erythropoietin Increased MetaADEDB
Blood Fibrinogen Increased MetaADEDB
Blood Immunoglobulin M Decreased MetaADEDB
Blood Iron Increased MetaADEDB
Blood Ketone Body Increased MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Body Temperature Fluctuation MetaADEDB
Bone Marrow Depression MetaADEDB
Bone Marrow Failure MetaADEDB
Bone Marrow Toxicity MetaADEDB
Bowel Sounds Abnormal MetaADEDB
Brain Natriuretic Peptide Increased MetaADEDB
Brain Neoplasm MetaADEDB
Breakthrough Bleeding MetaADEDB
Bronchiectasis MetaADEDB
Bundle Branch Block Left MetaADEDB
Bundle Branch Block Right MetaADEDB
Burkitt Lymphoma MetaADEDB
C-Reactive Protein Increased MetaADEDB
Caesarean Section MetaADEDB
Calculus Urethral MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Disease MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Failure MetaADEDB
Cardiac Hypertrophy MetaADEDB
Cardiac Malposition MetaADEDB
Cardiac Murmur MetaADEDB
Cardiogenic Shock MetaADEDB
Cardiomyopathy MetaADEDB
Cataract Operation MetaADEDB
Catatonia MetaADEDB
Central-Alveolar Hypoventilation MetaADEDB
Cephalhaematoma MetaADEDB
Cerebellar Hypoplasia MetaADEDB
Cerebral Toxoplasmosis MetaADEDB
Cerebral Ventricle Dilatation MetaADEDB
Cervical Discharge MetaADEDB
Cervical Incompetence MetaADEDB
Cervix Disorder MetaADEDB
Cervix Operation MetaADEDB
Chlamydial Infection MetaADEDB
Choking Sensation MetaADEDB
Cholecystectomies MetaADEDB
Cholecystitis Infective MetaADEDB
Chondrocalcinosis MetaADEDB
Chordee MetaADEDB
Chorioamnionitis MetaADEDB
Chromaturia MetaADEDB
Chromosomal Deletion MetaADEDB
Coagulation Factor Viii Level Decreased MetaADEDB
Complication Of Delivery MetaADEDB
Complication Of Pregnancy MetaADEDB
Complications Of Maternal Exposure To Therapeutic Drugs MetaADEDB
Conduct Disorder MetaADEDB
Confabulation MetaADEDB
Congenital Acrochordon MetaADEDB
Congenital Adrenal Gland Hypoplasia MetaADEDB
Congenital Anaemia MetaADEDB
Congenital Androgen Deficiency MetaADEDB
Congenital Aortic Stenosis MetaADEDB
Congenital Central Nervous System Anomaly MetaADEDB
Congenital Cerebral Cyst MetaADEDB
Congenital Choroid Plexus Cyst MetaADEDB
Congenital Cyst MetaADEDB
Congenital Diaphragmatic Anomaly MetaADEDB
Congenital Floppy Infant MetaADEDB
Congenital Genitourinary Abnormality MetaADEDB
Congenital Hepatobiliary Anomaly MetaADEDB
Congenital Hepatomegaly MetaADEDB
Congenital Hip Deformity MetaADEDB
Congenital Hydronephrosis MetaADEDB
Congenital Megacolon MetaADEDB
Congenital Mitochondrial Cytopathy MetaADEDB
Congenital Pulmonary Artery Anomaly MetaADEDB
Congenital Pulmonary Hypertension MetaADEDB
Congenital Pyelocaliectasis MetaADEDB
Congenital Tricuspid Valve Incompetence MetaADEDB
Congenital Urethral Anomaly MetaADEDB
Congenital Urinary Tract Obstruction MetaADEDB
Congenital Ventricular Septal Defect MetaADEDB
Congestive Cardiomyopathy MetaADEDB
Consciousness Fluctuating MetaADEDB
Cough MetaADEDB
Crackles Lung MetaADEDB
Cramp MetaADEDB
Cranial Sutures Widening MetaADEDB
Craniosynostosis MetaADEDB
Crying MetaADEDB
Cryptorchidism MetaADEDB
Cyst MetaADEDB
Cystic Fibrosis MetaADEDB
Cytomegalovirus Enterocolitis MetaADEDB
Cytomegalovirus Test MetaADEDB
Dawn Phenomenon MetaADEDB
Deafness MetaADEDB
Deafness Unilateral MetaADEDB
Death MetaADEDB
Death Neonatal MetaADEDB
Decreased Libido MetaADEDB
Deep Vein Thromboses MetaADEDB
Deformity Thorax MetaADEDB
Dengue Fever MetaADEDB
Dental Abscess MetaADEDB
Dermographism MetaADEDB
Dextrocardia MetaADEDB
Diabetic Acidosis MetaADEDB
Diabetic Complication MetaADEDB
Diabetic Ketoacidotic Hyperglycaemic Coma MetaADEDB
Diabetic Neuropathy MetaADEDB
Diaphragmatic Aplasia MetaADEDB
Difficulty In Walking MetaADEDB
Dilatation Atrial MetaADEDB
Dilatation Ventricular MetaADEDB
Disseminated Cytomegaloviral Infection MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Dizziness MetaADEDB
Drug Exposure Before Pregnancy MetaADEDB
Drug Exposure During Pregnancy MetaADEDB
Drug Screen Positive MetaADEDB
Drug Withdrawal Headache MetaADEDB
Dysmenorrhea MetaADEDB
Dyspepsia MetaADEDB
Dyspnea Exertional MetaADEDB
Dyspnoea Paroxysmal Nocturnal MetaADEDB
Dysstasia MetaADEDB
Dystrophia Myotonica MetaADEDB
Ear Discharge MetaADEDB
Eating Disorder MetaADEDB
Ebstein Anomaly MetaADEDB
Ecg Signs Of Ventricular Hypertrophy MetaADEDB
Echocardiogram Abnormal MetaADEDB
Echography Abnormal MetaADEDB
Ectopic Pregnancies MetaADEDB
Edema Extremities MetaADEDB
Ejection Fraction Decreased MetaADEDB
Electrocardiogram Change MetaADEDB
Electrocardiogram St Segment Abnormal MetaADEDB
Elevated Triglycerides MetaADEDB
Encephalitis MetaADEDB
Encopresis MetaADEDB
Enlarged Liver MetaADEDB
Enlarged Spleen MetaADEDB
Epidural Lipomatosis MetaADEDB
Erectile Dysfunction MetaADEDB
Erosive Gastritis MetaADEDB
Erythropoiesis Abnormal MetaADEDB
Esophageal Cancer MetaADEDB
Extremity Pain MetaADEDB
Eyelid Ptosis Congenital MetaADEDB
Face Pain MetaADEDB
Facial Neuralgia MetaADEDB
Factor Ii Deficiency MetaADEDB
Factor V Deficiency MetaADEDB
Factor Viii Inhibition MetaADEDB
Faeces Pale MetaADEDB
Fallot Tetralogy MetaADEDB
False Positive Laboratory Result MetaADEDB
Fasciitis MetaADEDB
Fat Redistribution MetaADEDB
Fatigue MetaADEDB
Febrile Bone Marrow Aplasia MetaADEDB
Fibroids MetaADEDB
Foetal Alcohol Syndrome MetaADEDB
Foetal Cardiac Disorder MetaADEDB
Foetal Disorder MetaADEDB
Foetal Distress Syndrome MetaADEDB
Foetal Growth Retardation MetaADEDB
Foetal Heart Rate MetaADEDB
Foetal Movements Decreased MetaADEDB
Foetal-Maternal Haemorrhage MetaADEDB
Fracture Nonunion MetaADEDB
Full Blood Count Decreased MetaADEDB
Full Blood Count Increased MetaADEDB
Fungal Disease MetaADEDB
Furuncle MetaADEDB
Galactosaemia MetaADEDB
Gallop Rhythm Present MetaADEDB
Gastric Fluid Analysis Abnormal MetaADEDB
Gastric Hyperplasia MetaADEDB
Gastric Varices MetaADEDB
Gastroenteritis MetaADEDB
Gastroenteritis Shigella MetaADEDB
Gastrointestinal Inflammation MetaADEDB
Gastrointestinal Oedema MetaADEDB
Gastrointestinal Tract Mucosal Discolouration MetaADEDB
Genital Pruritus Female MetaADEDB
Genital Ulceration MetaADEDB
Gestational Diabetes MetaADEDB
Gingival Pain MetaADEDB
Glomerulonephritis Rapidly Progressive MetaADEDB
Glucose-6-Phosphate Dehydrogenase Deficiency MetaADEDB
Goiter MetaADEDB
Gonorrhea MetaADEDB
Gram Stain Negative MetaADEDB
Grunting MetaADEDB
Haemangioma MetaADEDB
Haemangioma Of Skin MetaADEDB
Haematotoxicity MetaADEDB
Haemorrhage Foetal MetaADEDB
Head Circumference Abnormal MetaADEDB
Heart Block Congenital MetaADEDB
Heart Valve Incompetence MetaADEDB
Hellp Syndrome MetaADEDB
Hepatic Congestion MetaADEDB
Hepatic Displacement MetaADEDB
Hepatic Enzyme MetaADEDB
Hepatic Enzyme Abnormal MetaADEDB
Hepatic Siderosis MetaADEDB
Hepatitis MetaADEDB
Hepatitis E MetaADEDB
Hepato-Lenticular Degeneration MetaADEDB
Hepatojugular Reflux MetaADEDB
Hepatosplenomegaly Neonatal MetaADEDB
Hepatotoxicity MetaADEDB
Herpes Simplex MetaADEDB
Herpes Zoster Ophthalmic MetaADEDB
High Density Lipoprotein Decreased MetaADEDB
Hilar Lymphadenopathy MetaADEDB
Hip Surgery MetaADEDB
Hodgkin Disease Mixed Cellularity Stage Unspecified MetaADEDB
Horner Syndrome MetaADEDB
Hydrocele MetaADEDB
Hydrocephalus MetaADEDB
Hydronephrosis MetaADEDB
Hydrops Foetalis MetaADEDB
Hyperbilirubinaemia Neonatal MetaADEDB
Hyperemesis Gravidarum MetaADEDB
Hyperlipasaemia MetaADEDB
Hypoalbuminaemia MetaADEDB
Hypogonadotropic Hypogonadism MetaADEDB
Hypoplastic Right Heart Syndrome MetaADEDB
Hypospadias MetaADEDB
Hypotonia MetaADEDB
Imminent Abortion MetaADEDB
Inappropriate Affect MetaADEDB
Infection Upper Respiratory MetaADEDB
Insulin-Requiring Type 2 Diabetes Mellitus MetaADEDB
International Normalised Ratio Decreased MetaADEDB
Intestinal Mass MetaADEDB
Jra MetaADEDB
Kaolin Cephalin Clotting Time Prolonged MetaADEDB
Kaposi Varicelliform Eruption MetaADEDB
Kidney Malformation MetaADEDB
Lactate Pyruvate Ratio Increased MetaADEDB
Late Developer MetaADEDB
Left Ventricular Hypertrophy MetaADEDB
Lethargy MetaADEDB
Leucopenia MetaADEDB
Leukopenia Neonatal MetaADEDB
Lipase MetaADEDB
Lipohypertrophy MetaADEDB
Live Birth MetaADEDB
Lividity MetaADEDB
Local Swelling MetaADEDB
Lyell MetaADEDB
Lymphedema MetaADEDB
Lymphocytes Decreased MetaADEDB
Macrocytosis MetaADEDB
Malaria MetaADEDB
Malignant Tumour Excision MetaADEDB
Mastication Disorder MetaADEDB
Mean Cell Volume Increased MetaADEDB
Mechanical Ventilation MetaADEDB
Meconium Abnormal MetaADEDB
Meconium In Amniotic Fluid MetaADEDB
Meconium Peritonitis MetaADEDB
Melanocytic Naevus MetaADEDB
Meningeal Irritation MetaADEDB
Meningocele MetaADEDB
Meniscus Lesion MetaADEDB
Mesenteric Vein Thrombosis MetaADEDB
Methylmalonic Aciduria MetaADEDB
Microcephaly MetaADEDB
Missed Labour MetaADEDB
Mitochondrial Dna Depletion MetaADEDB
Mitral Valve Atresia MetaADEDB
Mitral Valve Calcification MetaADEDB
Mononeuritis MetaADEDB
Mood Altered MetaADEDB
Mouth Pain MetaADEDB
Mouth Ulcer MetaADEDB
Multiple Congenital Abnormalities MetaADEDB
Multiple Myeloma MetaADEDB
Muscle Inflammation MetaADEDB
Naevus Flammeus MetaADEDB
Neonatal Aspiration MetaADEDB
Neural Tube Defect MetaADEDB
Neuromuscular Disorder MetaADEDB
Neuromyelitis Optica MetaADEDB
Neuropathic Pain MetaADEDB
Neuropathic Ulcer MetaADEDB
Neutropenic Sepsis MetaADEDB
Neutrophil Count Abnormal MetaADEDB
Neutrophil Count Decreased MetaADEDB
Nicotine Dependence MetaADEDB
Normal Delivery MetaADEDB
Normal Newborn MetaADEDB
Oligohydramnios MetaADEDB
Optic Atrophy MetaADEDB
Optic Nerve Disorder MetaADEDB
Optic Neuropathy MetaADEDB
Orthopnea MetaADEDB
Pallor MetaADEDB
Palpitation MetaADEDB
Papilloma MetaADEDB
Paranoia MetaADEDB
Parvovirus B19 Serology Positive MetaADEDB
Patent Ductus Arteriosis MetaADEDB
Pericardial Effusion MetaADEDB
Periodontal Destruction MetaADEDB
Peripheral Artery Aneurysm MetaADEDB
Perirectal Abscess MetaADEDB
Peritonitis Bacterial MetaADEDB
Persecutory Delusion MetaADEDB
Pharyngeal Neoplasm MetaADEDB
Pharyngotonsillitis MetaADEDB
Phimosis MetaADEDB
Phlebitis MetaADEDB
Pitting Oedema MetaADEDB
Placenta Praevia MetaADEDB
Placental Disorder MetaADEDB
Placental Insufficiency MetaADEDB
Placental Necrosis MetaADEDB
Plasmacytosis MetaADEDB
Pneumothorax MetaADEDB
Po2 Abnormal MetaADEDB
Polydactyly MetaADEDB
Polyhydramnios MetaADEDB
Portal Vein Thrombosis MetaADEDB
Post Traumatic Stress Disorder MetaADEDB
Postpartum Disorder MetaADEDB
Pre-Eclampsia MetaADEDB
Pregnancy Induced Hypertension MetaADEDB
Premature Baby MetaADEDB
Premature Labour MetaADEDB
Premature Rupture Of Membranes MetaADEDB
Premature Separation Of Placenta MetaADEDB
Prescribed Overdose MetaADEDB
Priapism MetaADEDB
Prostatic Abscess MetaADEDB
Protein Total Decreased MetaADEDB
Prothrombin Level Decreased MetaADEDB
Psoriasis MetaADEDB
Pulmonary Arrest MetaADEDB
Pulmonary Arterial Pressure MetaADEDB
Pulmonary Artery Stenosis MetaADEDB
Pulmonary Valve Stenosis MetaADEDB
Pus In Stool MetaADEDB
Radial Nerve Palsy MetaADEDB
Refractory Anaemia With An Excess Of Blasts MetaADEDB
Renal Aplasia MetaADEDB
Respiratory Depth Decreased MetaADEDB
Respiratory Disorder Neonatal MetaADEDB
Respiratory Tract Malformation MetaADEDB
Reticulocytopenia MetaADEDB
Retinoblastoma Bilateral MetaADEDB
Retinogram Abnormal MetaADEDB
Retrognathia MetaADEDB
Rhinitis MetaADEDB
Rhythm Idioventricular MetaADEDB
Right Atrial Dilatation MetaADEDB
Right Heart Failure MetaADEDB
Right Ventricular Hypertrophy MetaADEDB
Right Ventricular Systolic Pressure Increased MetaADEDB
Scan Abdomen Abnormal MetaADEDB
Schistosomiasis MetaADEDB
Scleral Discolouration MetaADEDB
Semen Volume Decreased MetaADEDB
Septic Arthritis Staphylococcal MetaADEDB
Serum Ferritin Increased MetaADEDB
Skin Hypertrophy MetaADEDB
Skin Neoplasm Excision MetaADEDB
Small For Dates Baby MetaADEDB
Solitary Kidney MetaADEDB
Spina Bifida MetaADEDB
Spinal Cord Injury MetaADEDB
Spine Malformation MetaADEDB
Spinocerebellar Disorder MetaADEDB
Spleen Disorder MetaADEDB
Staphylococcal Abscess MetaADEDB
Staphylococcal Bacteraemia MetaADEDB
Streptococcal Infection MetaADEDB
Syphilis Test Positive MetaADEDB
T-Lymphocyte Count Decreased MetaADEDB
Talipes MetaADEDB
Thalassaemia Alpha MetaADEDB
Thrombophlebitis MetaADEDB
Thyroglossal Cyst MetaADEDB
Tinnitus MetaADEDB
Tobacco Abuse MetaADEDB
Tongue Discolouration MetaADEDB
Tongue Disorder MetaADEDB
Tonsillar Hypertrophy MetaADEDB
Tracheal Stenosis MetaADEDB
Transient Ischaemic Attack MetaADEDB
Treatment Noncompliance MetaADEDB
Trichomoniasis MetaADEDB
Trisomy 15 MetaADEDB
Trisomy 18 MetaADEDB
Trisomy 21 MetaADEDB
Trisomy 8 MetaADEDB
Ultrasound Antenatal Screen MetaADEDB
Ultrasound Kidney MetaADEDB
Ultrasound Scan Abnormal MetaADEDB
Umbilical Cord Prolapse MetaADEDB
Umbilical Cord Vascular Disorder MetaADEDB
Umbilical Hernia MetaADEDB
Underweight MetaADEDB
Urethral Disorder MetaADEDB
Urinary Tract Malformation MetaADEDB
Urogenital Disorder MetaADEDB
Urosepsis MetaADEDB
Urticaria Generalised MetaADEDB
Vaginal Burning Sensation MetaADEDB
Vanishing Bile Duct Syndrome MetaADEDB
Vasa Praevia MetaADEDB
Vena Cava Thrombosis MetaADEDB
Ventricular Hypokinesia MetaADEDB
Vitamin B 12 Deficiency MetaADEDB
Weight Gain Poor MetaADEDB
Wound Infection MetaADEDB

InAADR: Drug-Protein-ADRs database