InAADR

Drug Information

Drug Name: Roflumilast (162401-32-3)
PubChem ID: 449193
SMILES: C1CC1COC2=C(C=CC(=C2)C(=O)NC3=C(C=NC=C3Cl)Cl)OC(F)F
InchiKey: MNDBXUUTURYVHR-UHFFFAOYSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 403.212
LogP: 5.0309
Ring Count: 2
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 60.45

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain ADReCS
Angioedema PROTECT
Anxiety ADReCS
Aspartate Aminotransferase Increased PROTECT
Asthenia PROTECT
Atrial Fibrillation ADReCS
Back Pain ADReCS
Blood Creatine Phosphokinase Increased PROTECT
Cardiac Fibrillation ADReCS
Completed Suicide PROTECT
Connective Tissue Disorder SIDER
Constipation PROTECT
Decreased Appetite ADReCS
Depression ADReCS
Diarrhoea ADReCS
Dizziness ADReCS
Dysgeusia PROTECT
Dyspepsia ADReCS
Fatigue PROTECT
Gamma-Glutamyltransferase Increased PROTECT
Gastritis ADReCS
Gastrointestinal Disorder SIDER
Gastrointestinal Pain ADReCS
Gastrooesophageal Reflux Disease PROTECT
Gynaecomastia PROTECT
Haematochezia PROTECT
Headache ADReCS
Hypersensitivity PROTECT
Infection ADReCS
Infestation SIDER
Infestation Nos SIDER
Influenza ADReCS
Insomnia ADReCS
Lung Neoplasm Malignant ADReCS
Malaise PROTECT
Mental Disorder SIDER
Muscle Spasms ADReCS
Muscular Weakness PROTECT
Myalgia PROTECT
Nausea ADReCS
Neoplasm Malignant ADReCS
Nervous System Disorder SIDER
Nervousness PROTECT
Pain ADReCS
Palpitations PROTECT
Pancreatitis ADReCS
Pancreatitis Acute ADReCS
Prostate Cancer ADReCS
Prostatic Disorder ADReCS
Rash PROTECT
Renal Failure ADReCS
Renal Failure Acute ADReCS
Respiratory Tract Infection PROTECT
Rhinitis ADReCS
Sinusitis ADReCS
Suicidal Behaviour PROTECT
Suicidal Ideation PROTECT
Tremor ADReCS
Urinary Tract Infection ADReCS
Urticaria PROTECT
Vertigo PROTECT
Vomiting ADReCS
Weight Decreased ADReCS

InAADR: Drug-Protein-ADRs database