| Drug Name: | Tranylcypromine (155-09-9) |
|---|---|
| PubChem ID: | 19493 |
| SMILES: | C1[C@H]([C@@H]1N)C2=CC=CC=C2 |
| InchiKey: | AELCINSCMGFISI-DTWKUNHWSA-N |
| Therapeutic Category: |
| Molecular Weight (dalton) | : | 133.194 |
| LogP | : | 1.5012 |
| Ring Count | : | 1 |
| Hydrogen Bond Acceptor Count | : | 1 |
| Hydrogen Bond Donor Count | : | 1 |
| Total Polar Surface Area | : | 26.02 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Selegiline (14611-51-9) | Hypotension | Synergistic | Not understood | Attempts to attenuate the 'cheese effect' Combined drug therapy in depressive illness |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|---|---|---|
| Long-Term Changes In Synaptic Function In The Brain | Growth factor ARC (Q9WV31) | Chronic treatment with antidepressant drugs induces Arc gene expression in specific regions across the rat forebrain@Up-regulation of Arc expression may be part of the process by which antidepressant drugs achieve long-term changes in synaptic function in the brain [ ADR Type 2 ] | Antidepressant drug treatment induces Arc gene expression in the rat brain |
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
|---|---|---|
| tyramine dopamine and tryptophan rich food | Hypertensive Crisis | Hypertensive crisis and cheese |
This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category