InAADR

Drug Information

Drug Name: Levacetylmethadol (1477-40-3)
PubChem ID: 15130
SMILES: CC[C@@H](C(C[C@H](C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2)OC(=O)C
InchiKey: XBMIVRRWGCYBTQ-AVRDEDQJSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 353.506
LogP: 4.6546
Ring Count: 2
Hydrogen Bond Acceptor Count: 3
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 29.54

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Selegiline (14611-51-9) Cardiac Arrhythmias Antagonistic Prolong the QT interval The involvement of cytochrome P450 3A4 in the N-demethylation of L-alpha-acetylmethadol (LAAM), norLAAM, and methadone

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference
Arrhythmias Potassium voltage-gated channel subfamily H member 2 (Q12809) Keynote review: in vitro safety pharmacology profiling: an essential tool for successful drug development

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source

InAADR: Drug-Protein-ADRs database