InAADR

Drug Information

Drug Name: Tenofovir (147127-20-6)
PubChem ID: 464205
SMILES: C[C@H](CN1C=NC2=C1N=CN=C2N)OCP(=O)(O)O
InchiKey: SGOIRFVFHAKUTI-ZCFIWIBFSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 287.216
LogP: -0.0512
Ring Count: 2
Hydrogen Bond Acceptor Count: 7
Hydrogen Bond Donor Count: 3
Total Polar Surface Area: 136.38

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
17-Hydroxyprogesterone Increased MetaADEDB
5'Nucleotidase Increased MetaADEDB
Abdominal Distension MetaADEDB
Abdominal Hernia MetaADEDB
Abdominal Pain ADReCS
Abdominal Pain ADReCS
Abnormal Dreams ADReCS
Abnormal Lfts MetaADEDB
Abortion MetaADEDB
Abortion Induced MetaADEDB
Abscess Drainage MetaADEDB
Accident MetaADEDB
Acidosis ADReCS
Acne Rosacea MetaADEDB
Acquired Immune Deficiency Syndrome MetaADEDB
Acquired Protein S Deficiency MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Tubular Necrosis ADReCS
Adenopathy MetaADEDB
Administration Site Pain MetaADEDB
Adrenal Insufficiency MetaADEDB
Adrenal Suppression MetaADEDB
Adrenogenital Syndrome MetaADEDB
Aids Dementia Complex MetaADEDB
Aids Related Complication MetaADEDB
Alanine Aminotransferase Abnormal MetaADEDB
Alanine Aminotransferase Increased ADReCS
Alcohol Interaction MetaADEDB
Allergic Reaction ADReCS
Alveolitis MetaADEDB
Amentia MetaADEDB
Aminoaciduria MetaADEDB
Anaemia ADReCS
Anal Cancer MetaADEDB
Angina Unstable MetaADEDB
Angioedema ADReCS
Anogenital Warts MetaADEDB
Anorexia ADReCS
Anxiety ADReCS
Aortic Regurgitation MetaADEDB
Aphthous Stomatitis MetaADEDB
Appendectomy MetaADEDB
Appendicitis MetaADEDB
Areflexia MetaADEDB
Arterial Stenosis MetaADEDB
Arthralgia ADReCS
Ascites MetaADEDB
Aseptic Necrosis Bone MetaADEDB
Aspartate Aminotransferase Increased ADReCS
Aspergillosis MetaADEDB
Asthenia ADReCS
Atrial Hypertrophy MetaADEDB
Atypical Mycobacterial Infection MetaADEDB
Autoimmune Hepatitis MetaADEDB
Azotaemia MetaADEDB
B-Cell Lymphoma MetaADEDB
Back Pain ADReCS
Bacterial Pneumonia MetaADEDB
Bacterial Toxaemia MetaADEDB
Behcet Syndrome MetaADEDB
Bicytopenia MetaADEDB
Bile Duct Obstruction MetaADEDB
Bile Duct Stone MetaADEDB
Biliary Dilatation MetaADEDB
Biliary Fibrosis MetaADEDB
Biopsy Bile Duct Abnormal MetaADEDB
Biopsy Liver Abnormal MetaADEDB
Birth Defect MetaADEDB
Birth Trauma MetaADEDB
Bleeding Varicose Vein MetaADEDB
Blepharoptosis MetaADEDB
Blood Alkaline Phosphatase Increased ADReCS
Blood Amylase Increased ADReCS
Blood Antidiuretic Hormone Increased MetaADEDB
Blood Bicarbonate Decreased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Blister MetaADEDB
Blood Cholesterol Increased ADReCS
Blood Creatine Increased MetaADEDB
Blood Creatine Phosphokinase Increased ADReCS
Blood Creatinine Increased ADReCS
Blood Glucose Increased ADReCS
Blood Hiv Rna MetaADEDB
Blood In Urine MetaADEDB
Blood Lactate Dehydrogenase Abnormal MetaADEDB
Blood Ph Decreased MetaADEDB
Blood Phosphorus Decreased ADReCS
Blood Phosphorus Increased MetaADEDB
Blood Triglycerides Increased ADReCS
Blood Uric Acid MetaADEDB
Body Fat Disorder PROTECT
Body Temperature Increased ADReCS
Bone Density Decreased PROTECT
Bone Marrow Failure MetaADEDB
Bone Marrow Toxicity MetaADEDB
Bone Pain ADReCS
Bone Tuberculosis MetaADEDB
Brain Herniation MetaADEDB
Brain Mass MetaADEDB
Brain Stem Haemorrhage MetaADEDB
Breakthrough Bleeding MetaADEDB
Breast Cancer Recurrent MetaADEDB
Breast Enlargement PROTECT
Cachectic MetaADEDB
Caesarean Section MetaADEDB
Calculus Urinary MetaADEDB
Candida Infection MetaADEDB
Candida Serology Positive MetaADEDB
Candidiasis Of Mouth MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Murmur MetaADEDB
Cardiac Tamponade MetaADEDB
Cardioactive Drug Level MetaADEDB
Cardiomyopathy MetaADEDB
Castleman Disease MetaADEDB
Catheter Sepsis MetaADEDB
Cd4 Lymphocytes Decreased MetaADEDB
Cd4 Lymphocytes Increased MetaADEDB
Central Nervous System Inflammation MetaADEDB
Cephalhaematoma MetaADEDB
Cerebellar Ataxia MetaADEDB
Cerebellar Syndrome MetaADEDB
Cerebral Haemorrhage MetaADEDB
Cerebral Toxoplasmosis MetaADEDB
Cerebral Vascular Disorder MetaADEDB
Cervical Dysplasia MetaADEDB
Chemotherapeutic Drug Level Increased MetaADEDB
Chest Pain ADReCS
Cholangiolitis MetaADEDB
Cholecystitis MetaADEDB
Cholecystitis Acute MetaADEDB
Chronic Hepatitis MetaADEDB
Cirrhosis MetaADEDB
Citrobacter Infection MetaADEDB
Coma MetaADEDB
Complications Of Maternal Exposure To Therapeutic Drugs MetaADEDB
Congenital Cyst MetaADEDB
Congenital Diaphragmatic Hernia MetaADEDB
Congenital Mitochondrial Cytopathy MetaADEDB
Congenital Mitral Valve Incompetence MetaADEDB
Congenital Musculoskeletal Anomaly MetaADEDB
Congenital Pyelocaliectasis MetaADEDB
Congenital Tricuspid Valve Atresia MetaADEDB
Congestive Cardiomyopathy MetaADEDB
Conjunctival Hyperaemia MetaADEDB
Convulsions Grand Mal MetaADEDB
Cough ADReCS
Cough Increased ADReCS
Crackles Lung MetaADEDB
Cryoglobulinaemia MetaADEDB
Cryptococcosis MetaADEDB
Cryptorchidism MetaADEDB
Cryptosporidiosis MetaADEDB
Csf Lymphocyte Count Increased MetaADEDB
Csf Pressure Increased MetaADEDB
Csf Protein MetaADEDB
Cushing Syndrome MetaADEDB
Cytogenetic Analysis Abnormal MetaADEDB
Cytolytic Hepatitis MetaADEDB
Cytomegalovirus Antibody Positive MetaADEDB
Cytomegalovirus Chorioretinitis MetaADEDB
Cytomegalovirus Gastritis MetaADEDB
Cytomegalovirus Myocarditis MetaADEDB
Cytomegalovirus Oesophagitis MetaADEDB
Cytomegalovirus Test MetaADEDB
Cytomegalovirus Viraemia MetaADEDB
Death MetaADEDB
Decreased Appetite ADReCS
Dehydration MetaADEDB
Depression ADReCS
Depression Suicidal MetaADEDB
Dermatitis ADReCS
Dermatitis Bullous ADReCS
Detached Retina MetaADEDB
Developmental Coordination Disorder MetaADEDB
Developmental Delay MetaADEDB
Diabetes MetaADEDB
Diabetes Insipidus ADReCS
Diabetes Mellitus ADReCS
Dialysis MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Diffuse Panbronchiolitis MetaADEDB
Dilatation Ventricular MetaADEDB
Diplopia MetaADEDB
Disease Of Liver MetaADEDB
Disease Recurrence MetaADEDB
Disorder Of Globe MetaADEDB
Dizziness ADReCS
Drug Abuser MetaADEDB
Drug Exposure During Pregnancy MetaADEDB
Drug Interaction MetaADEDB
Drug Interaction Potentiation MetaADEDB
Drug Resistance MetaADEDB
Drug Toxicity MetaADEDB
Dyspepsia ADReCS
Dyspnea Exertional MetaADEDB
Dyspnoea ADReCS
Dyspnoea Paroxysmal Nocturnal MetaADEDB
Ear Discomfort MetaADEDB
Ejection Fraction Abnormal MetaADEDB
Elevated Triglycerides MetaADEDB
Emesis MetaADEDB
Encephalitis MetaADEDB
Encephalitis Allergic MetaADEDB
Encephalitis Cytomegalovirus MetaADEDB
Encephalitis Viral MetaADEDB
Encephalopathy MetaADEDB
End Stage Aids MetaADEDB
Endocarditis MetaADEDB
Enlarged Liver MetaADEDB
Enlarged Spleen MetaADEDB
Epidural Lipomatosis MetaADEDB
Erection Increased MetaADEDB
Erosive Oesophagitis MetaADEDB
Eruption MetaADEDB
Eschar MetaADEDB
Extrasystoles MetaADEDB
Facial Wasting MetaADEDB
Factor Viii Deficiency MetaADEDB
Failure To Thrive MetaADEDB
Fallopian Tube Obstruction MetaADEDB
Fanconi Syndrome ADReCS
Fasting ADReCS
Fat Atrophy MetaADEDB
Fat Redistribution MetaADEDB
Fatigue ADReCS
Fatty Liver MetaADEDB
Febrile Neutropenia MetaADEDB
Femoral Neck Fracture MetaADEDB
Fibrin Degradation Products Increased MetaADEDB
Fibrosarcoma MetaADEDB
Flatulence ADReCS
Fluid Overload MetaADEDB
Foetal Distress Syndrome MetaADEDB
Food Aversion MetaADEDB
Gall Bladder MetaADEDB
Gallbladder Cancer MetaADEDB
Gallbladder Oedema MetaADEDB
Gallop Rhythm Present MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastric Hyperplasia MetaADEDB
Gastric Varices MetaADEDB
Gastroenteritis Cryptosporidial MetaADEDB
Gastroenteritis Viral MetaADEDB
Gastrointestinal Cancer Metastatic MetaADEDB
Gastrointestinal Disorder MetaADEDB
Gastrointestinal Pain ADReCS
Gastrointestinal Tract Mucosal Discolouration MetaADEDB
Gaze Palsy MetaADEDB
General Physical Health Deterioration MetaADEDB
Genotype Drug Resistance Test Positive MetaADEDB
Giardiasis MetaADEDB
Gliosis MetaADEDB
Globulinuria MetaADEDB
Glomerular Filtration Rate Decreased PROTECT
Glomerulonephritis MetaADEDB
Glucose Urine MetaADEDB
Glycosuria ADReCS
Granuloma MetaADEDB
Gynaecomastia MetaADEDB
Haemangioma MetaADEDB
Haemarthrosis MetaADEDB
Haematology Test MetaADEDB
Haematuria ADReCS
Haemoglobin Decreased ADReCS
Haemoglobin Increased MetaADEDB
Haemorrhage Intracranial MetaADEDB
Hairy Cell Leukaemia MetaADEDB
Headache ADReCS
Heart Sounds Abnormal MetaADEDB
Hellp Syndrome MetaADEDB
Hematoma Subdural MetaADEDB
Hepatic Artery Thrombosis MetaADEDB
Hepatic Enzyme MetaADEDB
Hepatic Enzyme Abnormal MetaADEDB
Hepatic Enzyme Increased ADReCS
Hepatic Failure MetaADEDB
Hepatic Fibrosis MetaADEDB
Hepatic Function Abnormal MetaADEDB
Hepatic Necrosis MetaADEDB
Hepatic Steatosis ADReCS
Hepatitis ADReCS
Hepatitis B MetaADEDB
Hepatitis B Dna Increased MetaADEDB
Hepatitis B Positive MetaADEDB
Hepatitis C MetaADEDB
Hepatojugular Reflux MetaADEDB
Hepatomegaly PROTECT
Hepatosplenomegaly MetaADEDB
Hepatotoxicity MetaADEDB
Herpes Simplex MetaADEDB
Herpes Zoster MetaADEDB
Hip Fracture MetaADEDB
Histoplasmosis Disseminated MetaADEDB
Hiv Disease MetaADEDB
Hiv Wasting Syndrome MetaADEDB
Hodgkin Disease MetaADEDB
Human Herpesvirus 8 Infection MetaADEDB
Hydrocele MetaADEDB
Hydrocephalus MetaADEDB
Hypercholesterolaemia PROTECT
Hypercreatininaemia MetaADEDB
Hyperglycaemia ADReCS
Hyperhidrosis ADReCS
Hyperlactacidaemia PROTECT
Hyperlipaemia MetaADEDB
Hypermagnesaemia MetaADEDB
Hypersensitivity ADReCS
Hypertriglyceridaemia PROTECT
Hypogonadism MetaADEDB
Hypokalaemia ADReCS
Hypophosphataemia ADReCS
Hypospadias MetaADEDB
Hypotonia MetaADEDB
Hypouricaemia MetaADEDB
Hypovolaemia MetaADEDB
Hypoxia MetaADEDB
Immune Reconstitution Inflammatory Syndrome PROTECT
Immune Reconstitution Syndrome MetaADEDB
Immunosuppressant Drug Level MetaADEDB
Impetigo MetaADEDB
Infection Susceptibility Increased MetaADEDB
Inflammation ADReCS
Ingrowing Nail MetaADEDB
Insomnia ADReCS
Insulin Resistance PROTECT
Intermittent Claudication MetaADEDB
Interstitial Nephritis MetaADEDB
Intracranial Aneurysm MetaADEDB
Iron Deficiency Anaemia MetaADEDB
Ischaemic Stroke MetaADEDB
Isosporiasis MetaADEDB
Joint Arthroplasty MetaADEDB
Kaposi Sarcoma MetaADEDB
Kidney Failure MetaADEDB
Klebsiella Infection MetaADEDB
Lactic Acidosis ADReCS
Late Developer MetaADEDB
Left Atrial Dilatation MetaADEDB
Left Ventricular Dysfunction MetaADEDB
Legionella MetaADEDB
Leukocyturia MetaADEDB
Lip Erosion MetaADEDB
Lipase MetaADEDB
Lipids Abnormal MetaADEDB
Lipids Increased MetaADEDB
Lipodystrophy ADReCS
Lipodystrophy Acquired ADReCS
Lipohypertrophy MetaADEDB
Liver Transplant MetaADEDB
Long Qt Syndrome MetaADEDB
Loss Of Weight MetaADEDB
Lymphocytosis MetaADEDB
Lymphoma MetaADEDB
Macroglossia MetaADEDB
Malignant Soft Tissue Neoplasm MetaADEDB
Maternal Death Affecting Foetus MetaADEDB
Maternal Drugs Affecting Foetus MetaADEDB
Mean Cell Volume Increased MetaADEDB
Medical Observation MetaADEDB
Meningitis Viral MetaADEDB
Mental Disorder MetaADEDB
Mental Retardation Severity Unspecified MetaADEDB
Metabolic Disorder PROTECT
Metastases To Lung MetaADEDB
Metastases To Lymph Nodes MetaADEDB
Methaemoglobinaemia MetaADEDB
Microglossia MetaADEDB
Micrognathia MetaADEDB
Mitochondrial Toxicity MetaADEDB
Mitral Valve Calcification MetaADEDB
Monarthritis MetaADEDB
Monoparesis MetaADEDB
Multifocal Leukoencephalopathy MetaADEDB
Multiple Drug Overdose MetaADEDB
Multiple-Drug Resistance MetaADEDB
Muscle Abscess MetaADEDB
Muscle Rupture MetaADEDB
Muscular Weakness ADReCS
Musculoskeletal Discomfort ADReCS
Myalgia ADReCS
Mycobacterial Infection MetaADEDB
Mycobacterium Avium Complex Infection MetaADEDB
Mycobacterium Kansasii Infection MetaADEDB
Mycobacterium Tuberculosis Infection MetaADEDB
Myopathy ADReCS
Nail Disorder MetaADEDB
Nasopharyngeal Cancer MetaADEDB
Nasopharyngitis ADReCS
Nausea ADReCS
Neck Mass MetaADEDB
Necrosis ADReCS
Necrotising Granulomatous Lymphadenitis MetaADEDB
Neoplasm Of Appendix MetaADEDB
Nephritic Syndrome MetaADEDB
Nephritis ADReCS
Nephrogenic Diabetes Insipidus ADReCS
Nephropathy Toxic MetaADEDB
Nephrotic Syndrome MetaADEDB
Neuritis ADReCS
Neuropathic Ulcer MetaADEDB
Neuropathy ADReCS
Neuropathy Peripheral ADReCS
Neutropenic Sepsis MetaADEDB
Neutrophil Count Decreased ADReCS
Neutrophilia MetaADEDB
Nodular Regenerative Hyperplasia MetaADEDB
Non-Hodgkin Lymphoma MetaADEDB
Normal Newborn MetaADEDB
Obstruction MetaADEDB
Obstructive Uropathy MetaADEDB
Odynophagia MetaADEDB
Oesophageal Adenocarcinoma MetaADEDB
Oesophageal Candidiasis MetaADEDB
Oesophageal Varices Haemorrhage MetaADEDB
Oliguria MetaADEDB
Ophthalmoplegia MetaADEDB
Opisthotonus MetaADEDB
Opportunistic Infection MetaADEDB
Optic Neuritis MetaADEDB
Organising Pneumonia MetaADEDB
Orthopnea MetaADEDB
Osteolysis MetaADEDB
Osteomalacia ADReCS
Osteonecrosis PROTECT
Pain ADReCS
Pancreatitis ADReCS
Pancreatitis Chronic MetaADEDB
Paraesthesia ADReCS
Paranoid Personality Disorder MetaADEDB
Parasite Stool Test MetaADEDB
Parathyroid Disorder ADReCS
Parkinson MetaADEDB
Parotid Gland Enlargement MetaADEDB
Parotid Gland Inflammation MetaADEDB
Percutaneous Coronary Intervention MetaADEDB
Perianal Abscess MetaADEDB
Periarthritis MetaADEDB
Pericardial Effusion MetaADEDB
Pericardial Rub MetaADEDB
Pericarditis MetaADEDB
Periostitis MetaADEDB
Peripheral Embolism MetaADEDB
Peripheral Ischaemia MetaADEDB
Peripheral Sensory Neuropathy ADReCS
Peritoneal Effusion MetaADEDB
Peritonitis Bacterial MetaADEDB
Persistent Left Superior Vena Cava MetaADEDB
Pharyngeal Erythema MetaADEDB
Placenta Praevia MetaADEDB
Placental Disorder MetaADEDB
Placental Transfusion Syndrome MetaADEDB
Pneumocystis Carinii Pneumonia MetaADEDB
Pneumocystis Jiroveci Pneumonia MetaADEDB
Pneumonia ADReCS
Pneumonia Cytomegaloviral MetaADEDB
Po2 MetaADEDB
Polydactyly MetaADEDB
Polyhydramnios MetaADEDB
Polyuria ADReCS
Portal Hypertension MetaADEDB
Portal Hypertensive Gastropathy MetaADEDB
Portal Vein Thrombosis MetaADEDB
Post Procedural Pain MetaADEDB
Post Thrombotic Syndrome MetaADEDB
Postoperative Respiratory Distress MetaADEDB
Premature Baby MetaADEDB
Premature Rupture Of Membranes MetaADEDB
Premature Separation Of Placenta MetaADEDB
Primary Effusion Lymphoma MetaADEDB
Progressive External Ophthalmoplegia MetaADEDB
Prostatic Abscess MetaADEDB
Protein Urine Present ADReCS
Proteinuria ADReCS
Pruritus ADReCS
Pseudomonal Bacteraemia MetaADEDB
Pseudomyxoma Peritonei MetaADEDB
Psychomotor Skills Impaired MetaADEDB
Psychoses MetaADEDB
Pulmonary Hypertension MetaADEDB
Pulmonary Infarction MetaADEDB
Pyelonephritis MetaADEDB
Pyrexia ADReCS
Radicular Syndrome MetaADEDB
Rash ADReCS
Rash Maculo-Papular ADReCS
Rash Pustular ADReCS
Renal Colic MetaADEDB
Renal Failure ADReCS
Renal Failure Acute ADReCS
Renal Impairment MetaADEDB
Renal Tubular Acidosis MetaADEDB
Renal Tubular Disorder ADReCS
Renal Tubular Necrosis ADReCS
Respiratory Tract Infection ADReCS
Restrictive Cardiomyopathy MetaADEDB
Retroperitoneal Neoplasm MetaADEDB
Retroviral Infection MetaADEDB
Rhabdomyolysis ADReCS
Rhinitis ADReCS
Rhonchi MetaADEDB
Right Ventricular Dysfunction MetaADEDB
Scleral Discolouration MetaADEDB
Selective Abortion MetaADEDB
Sex Hormone Binding Globulin Decreased MetaADEDB
Sinusitis ADReCS
Skin Discolouration ADReCS
Skin Hyperpigmentation ADReCS
Sleep Walking MetaADEDB
Small Intestinal Obstruction MetaADEDB
Somnolence ADReCS
Speech Disorder Developmental MetaADEDB
Splenic Abscess MetaADEDB
Staphylococcal Abscess MetaADEDB
Staphylococcal Bacteraemia MetaADEDB
Staphylococcal Infection MetaADEDB
Subarachnoid Haemorrhage MetaADEDB
Subcutaneous Abscess MetaADEDB
Sudden Hearing Loss MetaADEDB
Syphilis MetaADEDB
Systemic Candida MetaADEDB
Talipes MetaADEDB
Tearfulness MetaADEDB
Therapeutic Product Ineffective MetaADEDB
Therapy Non-Responder MetaADEDB
Thrombocytopenia ADReCS
Thrombophlebitis MetaADEDB
Torsade De Pointes MetaADEDB
Toxoplasmosis MetaADEDB
Transaminases Increased MetaADEDB
Trisomy 18 MetaADEDB
Tubulointerstitial Nephritis ADReCS
Upper Respiratory Tract Infection ADReCS
Urinary Tract Pain MetaADEDB
Urine Amphetamine Positive MetaADEDB
Urine Output Increased ADReCS
Urine Sodium MetaADEDB
Urticaria ADReCS
Urticaria Papular MetaADEDB
Uterine Contractions During Pregnancy MetaADEDB
Vaginal Lesion MetaADEDB
Vanishing Bile Duct Syndrome MetaADEDB
Venous Pressure Jugular Increased MetaADEDB
Vertigo Positional MetaADEDB
Viral Load MetaADEDB
Viral Load Decreased MetaADEDB
Viral Mutation Identified MetaADEDB
Visceral Leishmaniasis MetaADEDB
Vomiting ADReCS
Walking Disability MetaADEDB
Weight Decreased ADReCS

InAADR: Drug-Protein-ADRs database