| Drug Name: | Sildenafil (139755-83-2) |
|---|---|
| PubChem ID: | 5212 |
| SMILES: | CCCC1=NN(C2=C1NC(=NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)C |
| InchiKey: | BNRNXUUZRGQAQC-UHFFFAOYSA-N |
| Therapeutic Category: | Cardiovascular Agents, Enzyme Inhibitors, Phosphodiesterase 5 Inhibitors, Phosphodiesterase Inhibitors, Urological Agents, Vasodilator Agents |
| Molecular Weight (dalton) | : | 474.587 |
| LogP | : | 1.6109 |
| Ring Count | : | 3 |
| Hydrogen Bond Acceptor Count | : | 8 |
| Hydrogen Bond Donor Count | : | 1 |
| Total Polar Surface Area | : | 113.42 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
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This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
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This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
|---|---|---|
| Grapefruit Juice | Increased Adverse Effects | Food–drug interaction: grapefruit juice augments drug bioavailabilityFmechanism, extent and relevance |
| Grapefruit Juice | Vasodilatation | Interactions between grapefruit juice and cardiovascular drugs |
This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category