InAADR

Drug Information

Drug Name: duloxetine (136434-34-9)
PubChem ID: 60835
SMILES: CNCC[C@@H](C1=CC=CS1)OC2=CC=CC3=CC=CC=C32
InchiKey: ZEUITGRIYCTCEM-KRWDZBQOSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 297.423
LogP: 4.6309
Ring Count: 3
Hydrogen Bond Acceptor Count: 3
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 21.26

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort SIDER
Abdominal Hernia MetaADEDB
Abdominal Pain SIDER
Abdominal Pain SIDER
Abdominal Pain SIDER
Abdominal Sepsis MetaADEDB
Abdominal Tenderness SIDER
Abnormal Dreams SIDER
Abnormal Gait MetaADEDB
Abnormal Lfts MetaADEDB
Abnormal Movements MetaADEDB
Abnormal Sensation In Eye MetaADEDB
Abnormal Vision MetaADEDB
Accelerated Hypertension MetaADEDB
Accident MetaADEDB
Accidental Exposure MetaADEDB
Accidental Needle Stick MetaADEDB
Acetonaemia MetaADEDB
Aching Joints MetaADEDB
Acne SIDER
Acute Coronary Syndrome SIDER
Acute Graft Versus Host Disease MetaADEDB
Acute Respiratory Failure MetaADEDB
Acute Sinusitis MetaADEDB
Adenocarcinoma MetaADEDB
Administration Site Pain MetaADEDB
Adrenal Insufficiency MetaADEDB
Adverse Drug Effect MetaADEDB
Affect Lability SIDER
Aggression SIDER
Agitated MetaADEDB
Agitation SIDER
Agraphia MetaADEDB
Akathisia PROTECT
Alanine Aminotransferase Increased SIDER
Alcohol Consumption MetaADEDB
Alopecia SIDER
Alveolitis MetaADEDB
Alveoloplasty MetaADEDB
Amentia MetaADEDB
Anaemia SIDER
Anal Cancer Stage 0 MetaADEDB
Anaphylactic Reaction PROTECT
Anaphylactic Shock SIDER
Anger SIDER
Angina MetaADEDB
Angioedema SIDER
Angiopathy SIDER
Anhedonia MetaADEDB
Anhidrosis MetaADEDB
Animal Bite MetaADEDB
Anorexia SIDER
Anorgasmia SIDER
Anxiety PROTECT
Aortic Aneurysm SIDER
Aortic Dissection SIDER
Apathy SIDER
Aphthous Stomatitis SIDER
Apoptosis MetaADEDB
Application Site Irritation MetaADEDB
Application Site Scab MetaADEDB
Application Site Vesicles MetaADEDB
Aptyalism MetaADEDB
Arm Amputation MetaADEDB
Arrhythmia SIDER
Arrhythmia Supraventricular SIDER
Arterial Disorder SIDER
Arterial Pressure Nos Decreased MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Arthralgia SIDER
Arthritis Bacterial MetaADEDB
Aseptic Necrosis Bone MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Aspartate Aminotransferase Increased SIDER
Aspiration Bronchial MetaADEDB
Asthenia SIDER
Asthenopia MetaADEDB
Ataxia SIDER
Atrial Fibrillation SIDER
Atrial Flutter MetaADEDB
Atrial Tachycardia MetaADEDB
Atrioventricular Block MetaADEDB
Atrophy MetaADEDB
Attempted Suicide MetaADEDB
Attention Deficit/Hyperactivity Disorder MetaADEDB
Back Disorder MetaADEDB
Back Pain ADReCS
Balance Disorder MetaADEDB
Bedridden MetaADEDB
Benign Neoplasm MetaADEDB
Bereavement MetaADEDB
Bile Duct Stenosis MetaADEDB
Biliary Cirrhosis Primary MetaADEDB
Biliary Fibrosis MetaADEDB
Biopsy MetaADEDB
Biopsy Breast Abnormal MetaADEDB
Bipolar Disorder MetaADEDB
Blindness SIDER
Blood Alkaline Phosphatase Increased SIDER
Blood Bilirubin Increased SIDER
Blood Blister MetaADEDB
Blood Cholesterol MetaADEDB
Blood Cholesterol Increased SIDER
Blood Creatine Phosphokinase Increased PROTECT
Blood Creatinine Increased SIDER
Blood Glucose Increased PROTECT
Blood In Stool SIDER
Blood Potassium Decreased MetaADEDB
Blood Potassium Increased PROTECT
Blood Pressure Diastolic Decreased SIDER
Blood Pressure Increased SIDER
Blood Triglycerides Increased SIDER
Blood Urine Present MetaADEDB
Body Temperature Increased SIDER
Bone Density Decreased MetaADEDB
Bone Disorder MetaADEDB
Bone Fracture Spontaneous MetaADEDB
Bone Graft MetaADEDB
Bone Lesion MetaADEDB
Bone Pain MetaADEDB
Bradypnoea MetaADEDB
Brain Damage MetaADEDB
Brain Operation MetaADEDB
Breast Discharge MetaADEDB
Breast Disorder SIDER
Breast Necrosis MetaADEDB
Breath Odour SIDER
Bronchitis MetaADEDB
Bruise MetaADEDB
Bruxism SIDER
Bulging MetaADEDB
Bundle Branch Block SIDER
Bundle Branch Block Right SIDER
Burns Second Degree MetaADEDB
Burns Third Degree MetaADEDB
Candidiasis Of Mouth MetaADEDB
Carcinoid Syndrome MetaADEDB
Carcinoma Of The Colon MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Disorder SIDER
Cardiac Failure SIDER
Cardiac Failure Congestive SIDER
Cardiac Fibrillation SIDER
Cardiomyopathy MetaADEDB
Cataract MetaADEDB
Causalgia MetaADEDB
Central Venous Catheterisation MetaADEDB
Cerebral Circulatory Failure MetaADEDB
Cerebral Thrombosis MetaADEDB
Cervical Dysplasia MetaADEDB
Chest Pain PROTECT
Chills SIDER
Cholecystitis Chronic MetaADEDB
Chronic Hepatitis MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Cirrhosis MetaADEDB
Clostridial Infection MetaADEDB
Cold Extremities MetaADEDB
Cold Sweat SIDER
Coldness SIDER
Colitis SIDER
Colonic Polyp MetaADEDB
Completed Suicide SIDER
Confusional State SIDER
Congenital Pyelocaliectasis MetaADEDB
Conjunctivitis SIDER
Connective Tissue Disorder SIDER
Constipated MetaADEDB
Constipation SIDER
Contusion ADReCS
Convulsion SIDER
Coordination Abnormal SIDER
Coronary Artery Disease SIDER
Costochondritis MetaADEDB
Cough SIDER
Cramp Muscle SIDER
Creatinine Increased SIDER
Crying MetaADEDB
Cutaneous Candidiasis MetaADEDB
Cutaneous Mycosis MetaADEDB
Cyanosis MetaADEDB
Deafness MetaADEDB
Debridement MetaADEDB
Decreased Appetite SIDER
Decreased Interest MetaADEDB
Decreased Libido MetaADEDB
Deglutition Disorder MetaADEDB
Dehydration SIDER
Delusion MetaADEDB
Dental Caries MetaADEDB
Dental Fistula MetaADEDB
Dental Pain MetaADEDB
Dependence MetaADEDB
Depressed Mood MetaADEDB
Depressive Symptom MetaADEDB
Dermatitis SIDER
Dermatitis Contact SIDER
Dermatitis Exfoliative SIDER
Detachment Psychological SIDER
Device Failure MetaADEDB
Diabetes MetaADEDB
Diabetes Mellitus SIDER
Diabetes Mellitus Inadequate Control MetaADEDB
Diabetes Mellitus Insulin-Dependent MetaADEDB
Diabetes Mellitus Non-Insulin-Dependent MetaADEDB
Diabetic Neuropathy MetaADEDB
Diabetic Ulcer MetaADEDB
Diarrhoea SIDER
Diplopia SIDER
Discomfort SIDER
Disorientation SIDER
Dissociation SIDER
Disturbance In Attention SIDER
Disturbance In Sexual Arousal SIDER
Diverticulitis SIDER
Dizziness SIDER
Drowsiness MetaADEDB
Drug Administered At Inappropriate Site MetaADEDB
Drug Dose Omission MetaADEDB
Drug Ineffective MetaADEDB
Drug Prescribing Error MetaADEDB
Drug Withdrawal MetaADEDB
Dry Eye SIDER
Dry Mouth SIDER
Dysarthria SIDER
Dysgeusia SIDER
Dyskinesia SIDER
Dyslipidaemia SIDER
Dyspepsia SIDER
Dysphagia SIDER
Dysphonia MetaADEDB
Dysthymic Disorder MetaADEDB
Dysuria SIDER
Ear Congestion MetaADEDB
Ear Pain SIDER
Early Morning Awakening MetaADEDB
Ecchymosis SIDER
Economic Problem MetaADEDB
Eczema SIDER
Effusion MetaADEDB
Ejaculation Delayed SIDER
Ejaculation Disorder SIDER
Ejaculation Failure SIDER
Electrocardiogram Qt Interval Abnormal ADReCS
Emesis MetaADEDB
Emotional Distress MetaADEDB
Endocrine Disorder SIDER
Enlarged Liver MetaADEDB
Enterococcal Infection MetaADEDB
Epistaxis PROTECT
Erectile Dysfunction SIDER
Eructation SIDER
Erythema SIDER
Erythema Multiforme SIDER
Excessive Sleepiness MetaADEDB
Excoriation MetaADEDB
Extrapyramidal Disorder SIDER
Eye Burns MetaADEDB
Eye Disorder SIDER
Eye Pain MetaADEDB
Face Oedema SIDER
Fall PROTECT
Fat Tissue Increased MetaADEDB
Fatigue PROTECT
Fatty Liver MetaADEDB
Feeding Disorder ADReCS
Feeling Abnormal SIDER
Feeling Cold SIDER
Feeling Guilty MetaADEDB
Feeling Hot SIDER
Feeling Jittery SIDER
Feeling Of Body Temperature Change ADReCS
Female Sexual Dysfunction SIDER
Femur Fracture MetaADEDB
Fibroids MetaADEDB
Fibromyalgia MetaADEDB
Flank Pain MetaADEDB
Flat Affect SIDER
Flatulence SIDER
Flooding MetaADEDB
Flushing SIDER
Foot Fracture MetaADEDB
Fractured Pelvis Nos MetaADEDB
Fungal Disease MetaADEDB
Furuncle MetaADEDB
Gait Disturbance SIDER
Galactorrhoea SIDER
Gall Bladder MetaADEDB
Gambling MetaADEDB
Gastric Dilatation MetaADEDB
Gastric Disorder SIDER
Gastric Irritation SIDER
Gastric Ulcer SIDER
Gastritis SIDER
Gastroenteritis SIDER
Gastroenteritis Viral ADReCS
Gastrointestinal Disorder SIDER
Gastrointestinal Haemorrhage SIDER
Gastrointestinal Pain SIDER
General Physical Health Deterioration MetaADEDB
Genital Haemorrhage ADReCS
Gingivitis SIDER
Gingivitis Ulcerative MetaADEDB
Glaucoma SIDER
Glucose Urine MetaADEDB
Glycosylated Haemoglobin Increased PROTECT
Haematochezia SIDER
Haematoma MetaADEDB
Haemoglobin SIDER
Haemorrhage SIDER
Haemorrhagic Hepatic Cyst MetaADEDB
Hallucination SIDER
Head Injury MetaADEDB
Headache SIDER
Heart Rate Increased ADReCS
Hepatic Enzyme MetaADEDB
Hepatic Enzyme Increased PROTECT
Hepatic Failure PROTECT
Hepatic Steatosis SIDER
Hepatitis SIDER
Hernia Hiatal MetaADEDB
Hesitancy MetaADEDB
Homicidal Ideation MetaADEDB
Hormone Level Abnormal SIDER
Hot Flush SIDER
Hydronephrosis MetaADEDB
Hyperalimentation MetaADEDB
Hyperbaric Oxygen Therapy MetaADEDB
Hypercholesterolaemia SIDER
Hyperglycaemia SIDER
Hyperhidrosis SIDER
Hyperkeratosis SIDER
Hyperkinesia SIDER
Hyperlipidaemia SIDER
Hyperparathyroidism MetaADEDB
Hyperprolactinaemia SIDER
Hypersensitivity SIDER
Hypertension SIDER
Hypertensive SIDER
Hypertensive Crisis SIDER
Hypertonia MetaADEDB
Hypertriglyceridaemia SIDER
Hypoaesthesia SIDER
Hypoglycaemia SIDER
Hyponatraemia SIDER
Hypotension SIDER
Hypotension Orthostatic MetaADEDB
Hypothyroid MetaADEDB
Hypothyroidism SIDER
Ild MetaADEDB
Ill-Defined Disorder SIDER
Immune System Disorder SIDER
Impaired Driving Ability MetaADEDB
Impaired Gastric Emptying SIDER
Impaired Healing MetaADEDB
Impaired Self-Care MetaADEDB
Impingement Syndrome MetaADEDB
Impulsive Behaviour MetaADEDB
Inappropriate Antidiuretic Hormone Secretion SIDER
Inappropriate Schedule Of Drug Administration MetaADEDB
Incontinence SIDER
Incorrect Dose Administered MetaADEDB
Increased Appetite SIDER
Increased Tendency To Bruise SIDER
Infarction SIDER
Infection SIDER
Infestation SIDER
Infestation Nos SIDER
Influenza SIDER
Influenza Like Illness MetaADEDB
Infusion Site Mobility Decreased MetaADEDB
Initial Insomnia SIDER
Injection Site Cellulitis MetaADEDB
Injection Site Erythema MetaADEDB
Injection Site Infection MetaADEDB
Injection Site Irritation MetaADEDB
Injection Site Pruritus MetaADEDB
Injection Site Warmth MetaADEDB
Inner Ear Inflammation MetaADEDB
Insomnia PROTECT
Intention Tremor MetaADEDB
Intentional Drug Misuse MetaADEDB
Intermittent Explosive Disorder MetaADEDB
Intervertebral Disc Disorder MetaADEDB
Intestinal Functional Disorder SIDER
Intracranial Haematoma MetaADEDB
Iron Deficiency Anaemia MetaADEDB
Irritability ADReCS
Irritable Bowel Syndrome SIDER
Ischias MetaADEDB
Itch MetaADEDB
Jaundice SIDER
Jaw Cyst MetaADEDB
Jaw Disorder MetaADEDB
Joint Stiffness MetaADEDB
Keratitis Sicca MetaADEDB
Kidney Infection MetaADEDB
Kyphosis MetaADEDB
Laceration MetaADEDB
Large Intestinal Ulcer MetaADEDB
Laryngitis SIDER
Laziness MetaADEDB
Lethargy SIDER
Leukopenia SIDER
Leukoplakia Of Mouth MetaADEDB
Libido Decreased SIDER
Libido Disorder ADReCS
Libido Increased ADReCS
Lichenoid Keratosis MetaADEDB
Limb Discomfort MetaADEDB
Limb Injury MetaADEDB
Liver Injury PROTECT
Loss Of Consciousness SIDER
Loss Of Libido SIDER
Loss Of Weight MetaADEDB
Lumbar Spinal Stenosis MetaADEDB
Lung Neoplasm Malignant MetaADEDB
Lymphadenopathy SIDER
Lymphocytic Infiltration MetaADEDB
Macular Degeneration SIDER
Maculopathy SIDER
Malaise SIDER
Malignant Melanoma MetaADEDB
Mania SIDER
Mediastinal Disorder SIDER
Melaena SIDER
Meningioma MetaADEDB
Menopausal Disorder MetaADEDB
Menopausal Symptoms SIDER
Menopause SIDER
Menstrual Disorder SIDER
Mental Disorder SIDER
Mental Impairment MetaADEDB
Mental Status Changes MetaADEDB
Metabolic Syndrome MetaADEDB
Metastatic Pain MetaADEDB
Micturition Urgency SIDER
Middle Insomnia SIDER
Migraine SIDER
Mood Altered MetaADEDB
Mood Swings SIDER
Mouth Pain MetaADEDB
Movement Disorder MetaADEDB
Multifocal Leukoencephalopathy MetaADEDB
Multiple Myeloma MetaADEDB
Multiple Sclerosis MetaADEDB
Multiple Sclerosis Relapse MetaADEDB
Muscle Necrosis MetaADEDB
Muscle Spasms SIDER
Muscle Tightness SIDER
Muscle Twitching SIDER
Muscular Weakness SIDER
Musculoskeletal Discomfort SIDER
Musculoskeletal Disorder MetaADEDB
Musculoskeletal Pain PROTECT
Myalgia SIDER
Mydriasis PROTECT
Myelopathy MetaADEDB
Myocardial Infarction SIDER
Myoclonus SIDER
Nasopharyngitis SIDER
Nausea SIDER
Near Syncope MetaADEDB
Neck Pain SIDER
Negativism MetaADEDB
Nephrolithiasis MetaADEDB
Nephropathy SIDER
Nervous System Disorder SIDER
Nervousness SIDER
Neuralgia MetaADEDB
Neuroleptic Malignant Syndrome MetaADEDB
Neuromuscular Disorder MetaADEDB
Neuropathy Peripheral MetaADEDB
Night Sweats SIDER
Nightmare SIDER
No Match PROTECT
No Therapeutic Response MetaADEDB
Nocturia SIDER
Nodule MetaADEDB
Ocular Icterus MetaADEDB
Oedema SIDER
Oedema Peripheral SIDER
Oesophageal Disorder SIDER
Oesophageal Stenosis SIDER
Off Label Use MetaADEDB
Oliguria SIDER
Oral Infection MetaADEDB
Orgasm Abnormal SIDER
Oropharyngeal Pain SIDER
Orthostatic Hypotension SIDER
Osteoarthritis SIDER
Osteomyelitis MetaADEDB
Osteomyelitis Acute MetaADEDB
Osteopenia MetaADEDB
Osteosclerosis MetaADEDB
Oxygen Saturation Abnormal MetaADEDB
Pain MetaADEDB
Pain In Extremity SIDER
Palpitation MetaADEDB
Palpitations SIDER
Pancreatic Duct Stenosis MetaADEDB
Pancreatitis MetaADEDB
Panic Attack MetaADEDB
Paraesthesia SIDER
Paraesthesia Oral SIDER
Paranoia MetaADEDB
Penis Disorder SIDER
Peripheral Coldness SIDER
Phantom Pain MetaADEDB
Pharyngeal Oedema SIDER
Pharyngitis SIDER
Pharyngolaryngeal Pain SIDER
Phlebitis SIDER
Phobia MetaADEDB
Phosphatase Alkaline Increased SIDER
Photopsia SIDER
Photosensitive Rash MetaADEDB
Photosensitivity SIDER
Photosensitivity Reaction SIDER
Pituitary Tumour Recurrent MetaADEDB
Plasmacytoma MetaADEDB
Pleurisy MetaADEDB
Pollakiuria SIDER
Polymyositis MetaADEDB
Polyneuropathy MetaADEDB
Polyuria SIDER
Poor Peripheral Circulation MetaADEDB
Poor Quality Sleep PROTECT
Portal Vein Phlebitis MetaADEDB
Postural Orthostatic Tachycardia Syndrome MetaADEDB
Precancerous Cells Present MetaADEDB
Pressure Of Speech SIDER
Proctalgia MetaADEDB
Product Quality Issue MetaADEDB
Prurigo SIDER
Pruritus SIDER
Pruritus Allergic MetaADEDB
Pruritus Generalised MetaADEDB
Psoriasis MetaADEDB
Pulmonary Hypertension MetaADEDB
Pulmonary Mass MetaADEDB
Pupillary Light Reflex Tests Abnormal MetaADEDB
Pyrexia ADReCS
Rash SIDER
Rash Erythematous SIDER
Respiratory Failure MetaADEDB
Respiratory Tract Infection SIDER
Restless Legs Syndrome SIDER
Restlessness PROTECT
Retinal Detachment SIDER
Rhinitis Seasonal SIDER
Rib Fracture MetaADEDB
Rigors SIDER
Scar MetaADEDB
Scleromalacia MetaADEDB
Seasonal Allergy SIDER
Sedation SIDER
Seizures SIDER
Sensitivity Of Teeth MetaADEDB
Serotonin Syndrome PROTECT
Sexual Dysfunction SIDER
Shock SIDER
Shock Haemorrhagic MetaADEDB
Sicca Syndrome SIDER
Sickness SIDER
Skin Haemorrhage MetaADEDB
Skin Laceration MetaADEDB
Skin Ulcer SIDER
Sleep Attacks MetaADEDB
Sleep Disorder SIDER
Sluggishness SIDER
Somnolence SIDER
Speech Disorder MetaADEDB
Sphincter Of Oddi Dysfunction MetaADEDB
Spinal Column Stenosis MetaADEDB
Spinal Compression Fracture MetaADEDB
Spinal Deformity MetaADEDB
Spinal Fracture MetaADEDB
Spinal Osteoarthritis MetaADEDB
Spinning Sensation MetaADEDB
Squamous Cell Carcinoma Of Skin MetaADEDB
Stevens-Johnson Syndrome PROTECT
Stomatitis SIDER
Suicidal Behaviour PROTECT
Suicidal Ideation PROTECT
Suicide Attempt ADReCS
Sweating SIDER
Sweating Increased SIDER
Swelling SIDER
Swollen Tongue MetaADEDB
Syncope SIDER
Tachycardia SIDER
Temporomandibular Joint Syndrome MetaADEDB
Tenderness SIDER
Tension SIDER
Terminal Insomnia SIDER
Testicular Pain ADReCS
Thinking Abnormal MetaADEDB
Thirst SIDER
Throat Tightness SIDER
Thrombocytopenia SIDER
Thyroid Disease MetaADEDB
Tinea MetaADEDB
Tinnitus SIDER
Tongue Disorder MetaADEDB
Tonsillar Disorder MetaADEDB
Tooth Disease MetaADEDB
Tooth Extraction MetaADEDB
Tooth Fracture MetaADEDB
Tooth Infection MetaADEDB
Transfusion Reaction MetaADEDB
Tremor SIDER
Trismus SIDER
Ulcer SIDER
Upper Limb Fracture MetaADEDB
Upper Respiratory Tract Infection SIDER
Upset Stomach SIDER
Urethral Disorder SIDER
Urinary Hesitation SIDER
Urinary Incontinence SIDER
Urinary Retention SIDER
Urinary Tract Disorder SIDER
Urinary Tract Infection SIDER
Urine Colour Abnormal MetaADEDB
Urine Flow Decreased SIDER
Urine Odour Abnormal SIDER
Urine Output SIDER
Urine Output Increased SIDER
Urticaria SIDER
Vertigo SIDER
Violence-Related Symptom MetaADEDB
Viral Diarrhoea SIDER
Viral Haemorrhagic Cystitis MetaADEDB
Viral Load MetaADEDB
Vision Blurred SIDER
Visual Acuity Reduced SIDER
Visual Disturbance SIDER
Visual Impairment SIDER
Vital Capacity Decreased ADReCS
Vomiting SIDER
Weakness SIDER
Weight Decreased SIDER
Weight Gain MetaADEDB
Weight Increased SIDER
White Blood Cell Count Increased SIDER
Withdrawal Syndrome PROTECT
Wound MetaADEDB
Wound Treatment MetaADEDB
Wrong Technique In Drug Usage Process MetaADEDB
Yawning SIDER

InAADR: Drug-Protein-ADRs database