InAADR

Drug Information

Drug Name: Trichlormethiazide (133-67-5)
PubChem ID: 5560
SMILES: C1=C2C(=CC(=C1Cl)S(=O)(=O)N)S(=O)(=O)NC(N2)C(Cl)Cl
InchiKey: LMJSLTNSBFUCMU-UHFFFAOYSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 380.662
LogP: 0.821
Ring Count: 1
Hydrogen Bond Acceptor Count: 5
Hydrogen Bond Donor Count: 3
Total Polar Surface Area: 118.36

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Mass MetaADEDB
Abnormal Gait MetaADEDB
Accelerated Hypertension MetaADEDB
Actinomycosis MetaADEDB
Acute Kidney Injury MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Promyelocytic Leukaemia MetaADEDB
Adams-Stokes Syndrome MetaADEDB
Adenitis MetaADEDB
Adenocarcinoma MetaADEDB
Adenopathy MetaADEDB
Adh Inappropriate MetaADEDB
Adrenal Insufficiency MetaADEDB
Adynamic Ileus MetaADEDB
Agranulocytoses MetaADEDB
Agraphia MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Alcohol Interaction MetaADEDB
Allergic Transfusion Reaction MetaADEDB
Altered State Of Consciousness MetaADEDB
Alveolar Soft Part Sarcoma MetaADEDB
Amentia MetaADEDB
Anaemia MetaADEDB
Angina MetaADEDB
Angioplasty MetaADEDB
Anorexia MetaADEDB
Anti-Insulin Antibody MetaADEDB
Anti-Insulin Antibody Positive MetaADEDB
Antibody Test MetaADEDB
Aortic Aneurysm MetaADEDB
Apathy MetaADEDB
Aphthous Stomatitis MetaADEDB
Arteriosclerosis Obliterans MetaADEDB
Arthritis Rheumatoid MetaADEDB
Ascites MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Atrioventricular Block MetaADEDB
Atrophy MetaADEDB
Autoimmune Thyroiditis MetaADEDB
Azotaemia MetaADEDB
Bacterial Toxaemia MetaADEDB
Behcet Syndrome MetaADEDB
Bence Jones Protein Urine MetaADEDB
Bicytopenia MetaADEDB
Black Stools MetaADEDB
Blood Albumin Abnormal MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Cholinesterase MetaADEDB
Blood Corticotrophin MetaADEDB
Blood Cortisol Decreased MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Creatinine MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood Immunoglobulin E MetaADEDB
Blood Immunoglobulin G Increased MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Pressure Diastolic Decreased MetaADEDB
Blood Pressure Inadequately Controlled MetaADEDB
Blood Pressure Systolic Increased MetaADEDB
Blood Sodium MetaADEDB
Blood Sodium Increased MetaADEDB
Blood Triglycerides Increased MetaADEDB
Blood Urea Increased MetaADEDB
Blood Uric Acid MetaADEDB
Body Temperature Increased MetaADEDB
Bone Cancer Metastatic MetaADEDB
Bone Fracture MetaADEDB
Bone Inflammation MetaADEDB
Bone Marrow Failure MetaADEDB
Bradycardia MetaADEDB
Brain Natriuretic Peptide Increased MetaADEDB
Brain Oedema MetaADEDB
Breast Enlargement MetaADEDB
Bronchoalveolar Lavage MetaADEDB
Bronchostenosis MetaADEDB
C-Reactive Protein Increased MetaADEDB
Cardiac Failure MetaADEDB
Cardiac Failure Acute MetaADEDB
Cardiac Failure Chronic MetaADEDB
Cardiac Pacemaker Insertion MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiogenic Shock MetaADEDB
Cartilage Development Disorder MetaADEDB
Cataract MetaADEDB
Cd4 Lymphocytes Decreased MetaADEDB
Cd8 Lymphocytes Decreased MetaADEDB
Cell Marker Increased MetaADEDB
Cerebral Artery Embolism MetaADEDB
Cerebral Artery Stenosis MetaADEDB
Cerebral Infarct MetaADEDB
Chemotherapeutic Drug Level Increased MetaADEDB
Cholangiolitis MetaADEDB
Chromaturia MetaADEDB
Chronic Kidney Disease MetaADEDB
Colitis Collagenous MetaADEDB
Color Blindness MetaADEDB
Condition Aggravated MetaADEDB
Constipated MetaADEDB
Contact Dermatitis MetaADEDB
Coughing Blood MetaADEDB
Csf Monocyte Count Decreased MetaADEDB
Csf Monocyte Count Increased MetaADEDB
Cubital Tunnel Syndrome MetaADEDB
Decreased Activity MetaADEDB
Decreased Interest MetaADEDB
Dehydration MetaADEDB
Dental Abscess MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Depressive Disorder Major MetaADEDB
Dermatitis Bullous MetaADEDB
Dermatitis Exfoliative MetaADEDB
Dermatitis Medicamentosa MetaADEDB
Detachment Of Retinal Pigment Epithelium MetaADEDB
Device Interaction MetaADEDB
Diabetes MetaADEDB
Diabetic Gangrene MetaADEDB
Diabetic Nephropathy MetaADEDB
Dialysis MetaADEDB
Disease Of Liver MetaADEDB
Disorder Lung MetaADEDB
Disorder Renal MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Disseminated Lupus Erythematosus MetaADEDB
Dizziness MetaADEDB
Drug Interaction Potentiation MetaADEDB
Duodenal Perforation MetaADEDB
Duodenal Ulcer MetaADEDB
Dysstasia MetaADEDB
Eczema MetaADEDB
Electrocardiogram Qt Corrected Interval Shortened MetaADEDB
Electrocardiogram T Wave Abnormal MetaADEDB
Electrocardiogram T Wave Inversion MetaADEDB
Encephalitis Allergic MetaADEDB
Enterocolitis MetaADEDB
Eosinophil Count Increased MetaADEDB
Eosinophilic Pneumonia MetaADEDB
Epidermolysis MetaADEDB
Eruption MetaADEDB
Excess Potassium MetaADEDB
Excessive Thirst MetaADEDB
Excoriation MetaADEDB
Eye Rolling MetaADEDB
Feeling Abnormal MetaADEDB
Folate Deficiency MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastric Cancer MetaADEDB
Gastric Ulcer MetaADEDB
Gastric Ulcer Haemorrhage MetaADEDB
Gastroenteritis MetaADEDB
Gastroenteritis Viral MetaADEDB
Gastrointestinal Perforation MetaADEDB
Gaze Palsy MetaADEDB
Glomerulonephritis MetaADEDB
Glomerulonephritis Rapidly Progressive MetaADEDB
Glucose Intolerance MetaADEDB
Glycosylated Haemoglobin Increased MetaADEDB
Haematology Test MetaADEDB
Haemodialysis MetaADEDB
Haemorrhagic Diathesis MetaADEDB
Hemiplegia MetaADEDB
Hepatic Function Abnormal MetaADEDB
Hepatic Neoplasm Malignant MetaADEDB
Herpes Simplex MetaADEDB
Hiccough MetaADEDB
Hyperammonaemia MetaADEDB
Hypertension MetaADEDB
Hypertensive Heart Disease MetaADEDB
Hypoglycaemia Neonatal MetaADEDB
Hypokalaemia MetaADEDB
Hypoproteinaemia MetaADEDB
Ild MetaADEDB
Ileal Ulcer MetaADEDB
Increased White Blood Cell Count MetaADEDB
Intestinal Obstruction MetaADEDB
Intubation MetaADEDB
Iron Deficiency Anaemia MetaADEDB
Ischaemic Stroke MetaADEDB
Laboratory Test Interference MetaADEDB
Lacunar Infarction MetaADEDB
Leucopenia MetaADEDB
Leukopenia Neonatal MetaADEDB
Lipase MetaADEDB
Lung Neoplasm Malignant MetaADEDB
Lymphocyte Count Decreased MetaADEDB
Lymphocyte Stimulation Test Positive MetaADEDB
Lymphocytes Decreased MetaADEDB
Marasmus MetaADEDB
Markedly Reduced Dietary Intake MetaADEDB
Metabolic Encephalopathy MetaADEDB
Metastases To Liver MetaADEDB
Mucosal Erosion MetaADEDB
Multi-Organ Failure MetaADEDB
Multiple Myeloma MetaADEDB
Myoglobin Blood Increased MetaADEDB
Nasal Congestion MetaADEDB
Nasopharyngitis MetaADEDB
Neonatal Asphyxia MetaADEDB
Neoplasia MetaADEDB
Nephrogenic Anaemia MetaADEDB
Nephrogenic Diabetes Insipidus MetaADEDB
Neumonia MetaADEDB
Neurosis MetaADEDB
Nutritional Condition Abnormal MetaADEDB
Oliguria MetaADEDB
Orbital Oedema MetaADEDB
Osteoarthritis MetaADEDB
Otorhinolaryngological Surgery MetaADEDB
Palmar-Plantar Erythrodysaesthesia Syndrome MetaADEDB
Pancreatic Cancer MetaADEDB
Panniculitis MetaADEDB
Paronychia MetaADEDB
Percutaneous Coronary Intervention MetaADEDB
Peritoneal Dialysis MetaADEDB
Phlebitis Infective MetaADEDB
Platelet Count MetaADEDB
Pleural Effusion MetaADEDB
Pneumonia Mycoplasmal MetaADEDB
Poriomania MetaADEDB
Posture Abnormal MetaADEDB
Primary Sequestrum MetaADEDB
Prinzmetal Angina MetaADEDB
Productive Cough MetaADEDB
Prostate Cancer Stage Iv MetaADEDB
Pruritus Generalised MetaADEDB
Pulmonary Alveolar Haemorrhage MetaADEDB
Pulmonary Congestion MetaADEDB
Pulmonary Hypoplasia MetaADEDB
Reflux Esophagitis MetaADEDB
Renal Failure Neonatal MetaADEDB
Renal Impairment MetaADEDB
Residual Urine MetaADEDB
Rhabdomyolysis MetaADEDB
Rhinorrhea MetaADEDB
Right Heart Failure MetaADEDB
Scrotal Ulcer MetaADEDB
Sinus Arrest Cardiac MetaADEDB
Sinus Bradycardia MetaADEDB
Small For Dates Baby MetaADEDB
Small Intestine Carcinoma MetaADEDB
Smallpox MetaADEDB
Soliloquy MetaADEDB
Solitary Kidney MetaADEDB
Subcutaneous Haematoma MetaADEDB
Sudden Death MetaADEDB
Surgical Vascular Shunt MetaADEDB
Thrombotic Stroke MetaADEDB
Tongue Discolouration MetaADEDB
Tooth Extraction MetaADEDB
Toxic Skin Eruption MetaADEDB
Tumour Marker Increased MetaADEDB
Ventricular Hypokinesia MetaADEDB
Vitreous Haemorrhage MetaADEDB
Wolff-Parkinson-White Syndrome MetaADEDB

InAADR: Drug-Protein-ADRs database