InAADR

Drug Information

Drug Name: Escitalopram (128196-01-0)
PubChem ID: 146570
SMILES: CN(C)CCC[C@@]1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F
InchiKey: WSEQXVZVJXJVFP-FQEVSTJZSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 324.399
LogP: 3.81298
Ring Count: 2
Hydrogen Bond Acceptor Count: 3
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 36.26

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Haloperidol (52-86-8) Akathisia Synergistic Escitalopram is an inhibitor of the cytochrome P450 isoenzyme CYP2D6, and may therefore inhibit haloperidol metabolism A Review of its Use in the Management of Major Depressive Disorder
Haloperidol (52-86-8) Parkinsonism Synergistic Escitalopram is an inhibitor of the cytochrome P450 isoenzyme CYP2D6, and may therefore inhibit haloperidol metabolism A Review of its Use in the Management of Major Depressive Disorder

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Cramp ADReCS
Abdominal Discomfort ADReCS
Abdominal Pain ADReCS
Abnormal Gait ADReCS
Abnormal Vision ADReCS
Abortion Spontaneous ADReCS
Acute Psychosis ADReCS
Aggression ADReCS
Agitation ADReCS
Agranulocytosis ADReCS
Akathisia ADReCS
Allergic Reaction ADReCS
Allergy ADReCS
Alopecia ADReCS
Amnesia ADReCS
Anaemia ADReCS
Anaphylactic Reaction ADReCS
Anger ADReCS
Angioedema ADReCS
Anorgasmia ADReCS
Anxiety ADReCS
Apathy ADReCS
Aplastic Anaemia ADReCS
Arthralgia ADReCS
Asthenia ADReCS
Ataxia ADReCS
Atrial Fibrillation ADReCS
Atrioventricular Block ADReCS
Blood Bilirubin Increased ADReCS
Blood Disorder ADReCS
Blood Pressure Diastolic Abnormal ADReCS
Blood Pressure Systolic ADReCS
Blood Test Abnormal ADReCS
Bradycardia ADReCS
Bronchitis ADReCS
Bronchospasm ADReCS
Cardiac Failure ADReCS
Cerebrovascular Accident ADReCS
Chest Pain ADReCS
Chills ADReCS
Choreoathetosis ADReCS
Completed Suicide ADReCS
Confusional State ADReCS
Constipation ADReCS
Convulsion ADReCS
Cough ADReCS
Decreased Appetite ADReCS
Deep Vein Thrombosis ADReCS
Delirium ADReCS
Delusion ADReCS
Depersonalisation ADReCS
Depression ADReCS
Depression Aggravated ADReCS
Derealisation ADReCS
Dermatitis ADReCS
Diabetes Mellitus ADReCS
Diarrhoea ADReCS
Diplopia ADReCS
Disorientation ADReCS
Disturbance In Attention ADReCS
Dizziness ADReCS
Dreaming Abnormal ADReCS
Dry Mouth ADReCS
Dysarthria ADReCS
Dyskinesia ADReCS
Dysmenorrhoea ADReCS
Dyspepsia ADReCS
Dysphagia ADReCS
Dyspnoea ADReCS
Dystonia ADReCS
Dysuria ADReCS
Ecchymosis ADReCS
Ejaculation Disorder ADReCS
Electrocardiogram Qt Prolonged ADReCS
Epidermal Necrosis ADReCS
Epistaxis ADReCS
Erectile Dysfunction ADReCS
Erythema ADReCS
Erythema Multiforme ADReCS
Extrapyramidal Disorder ADReCS
Fall ADReCS
Fatigue ADReCS
Feeding Disorder ADReCS
Feeling Abnormal ADReCS
Flatulence ADReCS
Flushing ADReCS
Gastroenteritis ADReCS
Gastrointestinal Haemorrhage ADReCS
Gastrooesophageal Reflux Disease ADReCS
Glaucoma ADReCS
Grand Mal Convulsion ADReCS
Haemolytic Anaemia ADReCS
Hallucination ADReCS
Headache ADReCS
Heart Rate Decreased ADReCS
Heartburn ADReCS
Hepatic Enzyme Increased ADReCS
Hepatic Failure ADReCS
Hepatic Necrosis ADReCS
Hepatitis ADReCS
Hepatitis Fulminant ADReCS
Hot Flush ADReCS
Hypercholesterolaemia ADReCS
Hyperglycaemia ADReCS
Hyperhidrosis ADReCS
Hyperprolactinaemia ADReCS
Hypersensitivity ADReCS
Hypertension ADReCS
Hypertensive Crisis ADReCS
Hypoaesthesia ADReCS
Hypoglycaemia ADReCS
Hypokalaemia ADReCS
Hyponatraemia ADReCS
Hypotension ADReCS
Idiopathic Thrombocytopenic Purpura ADReCS
Impotence ADReCS
Inappropriate Antidiuretic Hormone Secretion ADReCS
Increased Appetite ADReCS
Influenza Like Illness ADReCS
Infusion Site Pain ADReCS
Infusion Site Reaction ADReCS
Insomnia ADReCS
Intentional Self-Injury ADReCS
International Normalised Ratio Increased ADReCS
Irritability ADReCS
Joint Stiffness ADReCS
Lethargy ADReCS
Leukopenia ADReCS
Libido Decreased ADReCS
Malaise ADReCS
Mediastinal Disorder ADReCS
Menorrhagia ADReCS
Menstrual Disorder ADReCS
Migraine ADReCS
Mood Swings ADReCS
Muscle Spasms ADReCS
Muscular Weakness ADReCS
Musculoskeletal Pain ADReCS
Musculoskeletal Stiffness ADReCS
Myalgia ADReCS
Mydriasis ADReCS
Myocardial Infarction ADReCS
Myoclonus ADReCS
Nasal Congestion ADReCS
Nausea ADReCS
Neck Pain ADReCS
Neonatal Disorder ADReCS
Nervousness ADReCS
Nightmare ADReCS
Nystagmus ADReCS
Oedema ADReCS
Orthostatic Hypotension ADReCS
Ovulation Pain ADReCS
Pain In Extremity ADReCS
Pallor ADReCS
Palpitations ADReCS
Pancreatitis ADReCS
Panic Reaction ADReCS
Paraesthesia ADReCS
Paranoia ADReCS
Parkinsonian Rest Tremor ADReCS
Parkinsonism ADReCS
Peripheral Ischaemia ADReCS
Persistent Foetal Circulation ADReCS
Phlebitis ADReCS
Photosensitivity Reaction ADReCS
Pollakiuria ADReCS
Priapism ADReCS
Prothrombin Level Decreased ADReCS
Pulmonary Embolism ADReCS
Pulmonary Hypertension ADReCS
Pulmonary Oedema ADReCS
Pyrexia ADReCS
Rales ADReCS
Rash ADReCS
Rectal Haemorrhage ADReCS
Renal Failure Acute ADReCS
Restless Legs Syndrome ADReCS
Restlessness ADReCS
Rhabdomyolysis ADReCS
Rhinitis ADReCS
Rhonchi ADReCS
Self Injurious Behaviour ADReCS
Sinus Congestion ADReCS
Sinus Headache ADReCS
Sinus Operation ADReCS
Sinusitis ADReCS
Skin Discolouration ADReCS
Skin Necrosis ADReCS
Somnolence ADReCS
Speech Disorder ADReCS
Stevens-Johnson Syndrome ADReCS
Suicidal Ideation ADReCS
Suicide Attempt ADReCS
Syncope ADReCS
Tachycardia ADReCS
Tardive Dyskinesia ADReCS
Thinking Abnormal ADReCS
Thrombocytopenia ADReCS
Thrombophlebitis ADReCS
Thrombosis ADReCS
Tinnitus ADReCS
Toothache ADReCS
Torsade De Pointes ADReCS
Toxic Epidermal Necrolysis ADReCS
Tremor ADReCS
Urinary Retention ADReCS
Urinary Tract Infection ADReCS
Urinary Tract Obstruction ADReCS
Urine Analysis Abnormal ADReCS
Urticaria ADReCS
Ventricular Arrhythmia ADReCS
Ventricular Tachycardia ADReCS
Vertigo ADReCS
Vision Blurred ADReCS
Visual Disturbance ADReCS
Visual Impairment ADReCS
Vomiting ADReCS
Weight Abnormal ADReCS
Weight Decreased ADReCS
Weight Increased ADReCS
Wheezing ADReCS
Yawning ADReCS

InAADR: Drug-Protein-ADRs database