InAADR

Drug Information

Drug Name: Lafutidine (118288-08-7)
PubChem ID:
SMILES: C1CCN(CC1)CC2=CC(=NC=C2)OCC=CCNC(=O)CS(=O)CC3=CC=CO3
InchiKey: KMZQAVXSMUKBPD-DJWKRKHSSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 431.558
LogP: 2.6606
Ring Count: 2
Hydrogen Bond Acceptor Count: 6
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 84.67

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abscess Neck MetaADEDB
Acute Abdomen MetaADEDB
Acute Brain Syndrome MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Myocardial Infarction MetaADEDB
Acute Tonsillitis MetaADEDB
Adenocarcinoma MetaADEDB
Adh Inappropriate MetaADEDB
Adynamic Ileus MetaADEDB
Affect Lability MetaADEDB
Agitated MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Altered State Of Consciousness MetaADEDB
Amentia MetaADEDB
Anaemia MetaADEDB
Anorexia MetaADEDB
Aortic Aneurysm MetaADEDB
Aortic Aneurysm MetaADEDB
Aortic Dissection MetaADEDB
Aortic Stenosis MetaADEDB
Apathy MetaADEDB
Appetite Disorder MetaADEDB
Arthritis Bacterial MetaADEDB
Ascites MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Aspiration Pneumonia MetaADEDB
Asthma MetaADEDB
B-Cell Lymphoma MetaADEDB
Bacteria Urine Identified MetaADEDB
Bacterial Toxaemia MetaADEDB
Bence Jones Protein Urine MetaADEDB
Bilirubin Conjugated Increased MetaADEDB
Black Stools MetaADEDB
Bleb MetaADEDB
Blindness Unilateral MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Calcium Increased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Pressure Diastolic Decreased MetaADEDB
Blood Pressure Systolic Decreased MetaADEDB
Blood Urea Increased MetaADEDB
Blood Uric Acid MetaADEDB
Blood Urine Present MetaADEDB
Blood Zinc Decreased MetaADEDB
Body Temperature Increased MetaADEDB
Bone Fracture MetaADEDB
Bone Marrow Failure MetaADEDB
Brain Contusion MetaADEDB
Brain Natriuretic Peptide Increased MetaADEDB
Brain Oedema MetaADEDB
Bronchitis MetaADEDB
Burning Sensation Mucosal MetaADEDB
C-Reactive Protein Increased MetaADEDB
Candida Pneumonia MetaADEDB
Carcinoma Of The Cervix MetaADEDB
Carcinoma Of The Colon MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Failure MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Carotid Artery Aneurysm MetaADEDB
Cartilage Development Disorder MetaADEDB
Cell Marker Increased MetaADEDB
Cerebral Haemorrhage MetaADEDB
Cerebral Infarct MetaADEDB
Cerebrovascular Stenosis MetaADEDB
Cervicalgia MetaADEDB
Cheilitis MetaADEDB
Cholangitis Acute MetaADEDB
Cholecystitis Acute MetaADEDB
Chronic Allograft Nephropathy MetaADEDB
Chronic Kidney Disease MetaADEDB
Colonic Polyp MetaADEDB
Colorectal Cancer MetaADEDB
Condition Aggravated MetaADEDB
Conjunctival Deposit MetaADEDB
Constipated MetaADEDB
Coronary Angioplasty MetaADEDB
Cough MetaADEDB
Coughing Blood MetaADEDB
Crying MetaADEDB
Csf Lymphocyte Count Increased MetaADEDB
Csf Pressure Increased MetaADEDB
Cytomegalovirus Test Positive MetaADEDB
Dental Pain MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Dermatitides MetaADEDB
Dermatitis Medicamentosa MetaADEDB
Dialysis MetaADEDB
Diaphragmatic Rupture MetaADEDB
Disease Of Liver MetaADEDB
Disease Progression MetaADEDB
Disorder Renal MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Diverticulum Intestinal Haemorrhagic MetaADEDB
Duodenal Perforation MetaADEDB
Duodenal Ulcer MetaADEDB
Dyslalia MetaADEDB
Eczema MetaADEDB
Ejection Fraction Decreased MetaADEDB
Electrocardiogram St Segment Elevation MetaADEDB
Enterocolitis MetaADEDB
Eruption MetaADEDB
Erythema Multiforme MetaADEDB
Excess Potassium MetaADEDB
Fat Atrophy MetaADEDB
Fat Embolism MetaADEDB
Fat Tissue Increased MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastric Ulcer MetaADEDB
Gastrointestinal Perforation MetaADEDB
Gastrointestinal Stromal Tumour MetaADEDB
Globulinuria MetaADEDB
Glossitis MetaADEDB
Haemodialysis MetaADEDB
Haemorrhagic Anaemia MetaADEDB
Haemorrhagic Diathesis MetaADEDB
Hepatic Congestion MetaADEDB
Hepatic Function Abnormal MetaADEDB
Hepatic Neoplasm Malignant MetaADEDB
Hepatitis Fulminant MetaADEDB
Hepatosplenomegaly MetaADEDB
Hyperphosphataemia MetaADEDB
Hypertensive Heart Disease MetaADEDB
Hypoaesthesia Oral MetaADEDB
Hypoglycaemia Neonatal MetaADEDB
Hypopituitarism MetaADEDB
Ild MetaADEDB
Immunodeficiency MetaADEDB
Infusion Site Pain MetaADEDB
Infusion Site Swelling MetaADEDB
Interleukin-2 Receptor Increased MetaADEDB
Intervertebral Discitis MetaADEDB
Intestinal Obstruction MetaADEDB
Intracardiac Thrombus MetaADEDB
Intracranial Tumour Haemorrhage MetaADEDB
Kidney Transplant Rejection MetaADEDB
Lacrimation Increased MetaADEDB
Lacunar Infarction MetaADEDB
Large Intestine Perforation MetaADEDB
Leucine Aminopeptidase Increased MetaADEDB
Leukoencephalopathy MetaADEDB
Leukopenia Neonatal MetaADEDB
Lipase MetaADEDB
Liver Abscess MetaADEDB
Localised Oedema MetaADEDB
Long Qt Syndrome MetaADEDB
Lumbar Vertebral Fracture MetaADEDB
Lung Adenocarcinoma Metastatic MetaADEDB
Lyell MetaADEDB
Lymphocyte Stimulation Test Positive MetaADEDB
Malignant Neoplasm Progression MetaADEDB
Meningeal Irritation MetaADEDB
Mental Disorder MetaADEDB
Metastases To Adrenals MetaADEDB
Monarthritis MetaADEDB
Mood Altered MetaADEDB
Multiple Sclerosis Relapse MetaADEDB
Mycobacterium Tuberculosis Infection MetaADEDB
Nasopharyngitis MetaADEDB
Nephrotic Syndrome MetaADEDB
Neumonia MetaADEDB
Neuropathy Peripheral MetaADEDB
Neurosis MetaADEDB
Neutrophil Count Decreased MetaADEDB
Oesophageal Varices Haemorrhage MetaADEDB
Oliguria MetaADEDB
Opportunistic Infection MetaADEDB
Optic Disc Edema MetaADEDB
Optic Ischaemic Neuropathy MetaADEDB
Optic Nerve Disorder MetaADEDB
Oral Polypectomy MetaADEDB
Ovarian Enlargement MetaADEDB
Ovarian Germ Cell Teratoma Benign MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Palmar-Plantar Erythrodysaesthesia Syndrome MetaADEDB
Parotid Abscess MetaADEDB
Periodontitis MetaADEDB
Peritonitis MetaADEDB
Pharyngeal Haemorrhage MetaADEDB
Pharyngolaryngeal Pain MetaADEDB
Platelet Count MetaADEDB
Pleurodesis MetaADEDB
Pneumonia Cytomegaloviral MetaADEDB
Pneumonia Staphylococcal MetaADEDB
Polymyalgia Rheumatica MetaADEDB
Polyomavirus-Associated Nephropathy MetaADEDB
Post Procedural Haemorrhage MetaADEDB
Postoperative Fever MetaADEDB
Protein Total Decreased MetaADEDB
Prothrombin Time Prolonged MetaADEDB
Pulmonary Alveolar Haemorrhage MetaADEDB
Pulmonary Arrest MetaADEDB
Pulmonary Congestion MetaADEDB
Quadriplegia MetaADEDB
Rectal Perforation MetaADEDB
Renal Impairment MetaADEDB
Renin Increased MetaADEDB
Sclerosing Encapsulating Peritonitis MetaADEDB
Shunt Malfunction MetaADEDB
Sleep Walking MetaADEDB
Small Intestinal Stenosis MetaADEDB
Small Intestine Ulcer MetaADEDB
Speech Disorder MetaADEDB
Spinal Compression Fracture MetaADEDB
Spinning Sensation MetaADEDB
Status Epilepticus MetaADEDB
Subarachnoid Haemorrhage MetaADEDB
Subcutaneous Haematoma MetaADEDB
Subdural Haemorrhage MetaADEDB
Sudden Hearing Loss MetaADEDB
Suture Rupture MetaADEDB
Tachycardia Ventricular MetaADEDB
Tetany MetaADEDB
Tongue Discolouration MetaADEDB
Tonsillitis MetaADEDB
Torsade De Pointes MetaADEDB
Tuberculosis Test Positive MetaADEDB
Tumour Lysis Syndrome MetaADEDB
Urobilin Urine Present MetaADEDB
Ventricular Fibrillation MetaADEDB
Vertebral Artery Occlusion MetaADEDB
Vesical Fistula MetaADEDB
White Blood Cell Analysis Decreased MetaADEDB
Wound Decomposition MetaADEDB
Wound Drainage MetaADEDB

InAADR: Drug-Protein-ADRs database