InAADR

Drug Information

Drug Name: Remacemide (111686-79-4)
PubChem ID: 60510
SMILES: CC(CC1=CC=CC=C1)(C2=CC=CC=C2)NC(=O)CN.Cl
InchiKey: HYQMIUSWZXGTCC-UHFFFAOYSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 304.821
LogP: 2.6412
Ring Count: 2
Hydrogen Bond Acceptor Count: 2
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 55.12

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Carbamazepine (298-46-4) Raise Serum Carbamazepine Levels Synergistic Not fully understood, but in vitro studies indicate that remacemide inhibits the cytochrome P450 isoenzyme CYP3A4 Adjustment of carbamazepine dose to offset the effects of the interaction with remacemide hydrochloride in a double-blind, multicentre, add-on drug trial (CR2237) in refractory epileps

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source

InAADR: Drug-Protein-ADRs database