InAADR

Drug Information

Drug Name: Cefacetrile (10206-21-0)
PubChem ID: 91562
SMILES: CC(=O)OCC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)CC#N)SC1)C(=O)O
InchiKey: RRYMAQUWDLIUPV-BXKDBHETSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 339.329
LogP: -0.79822
Ring Count: 0
Hydrogen Bond Acceptor Count: 7
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 136.8

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Furosemide (54-31-9) Nephrotoxicity Antagonistic Cefacetrile is nephrotoxic, but why this should be increased by furosemide is not understood. It may possibly be related to a reduction in its clearance Possible interaction between cephacetrile and frusemide in rabbits and rats

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source

InAADR: Drug-Protein-ADRs database