Drugs Causing Hyperkeratosis: 199
Drug Name	CAS Number	Source
Acetaminophen	103-90-2	MetaADEDB
Acetylsalicylic acid	50-78-2	MetaADEDB
Acitretin	55079-83-9	ADReCS
Alendronate Sodium	121268-17-5	MetaADEDB
Alfentanil	71195-58-9	MetaADEDB
Allopurinol	315-30-0	MetaADEDB
Aminolevulinic acid	106-60-5	PROTECT
Amiodarone	1951-25-3	ADReCS
Amisulpride	53583-79-2	MetaADEDB
Amlodipine besylate	111470-99-6	MetaADEDB
Amoxicillin	26787-78-0	MetaADEDB
Aripiprazole	129722-12-9	ADReCS
Atenolol	29122-68-7	MetaADEDB
Azathioprine	446-86-6	MetaADEDB
Azelaic Acid	123-99-9	ADReCS
Azelastine	58581-89-8	MetaADEDB
Azithromycin	83905-01-5	MetaADEDB
Bacitracin	1405-87-4	MetaADEDB
Beclomethasone	4419-39-0	MetaADEDB
Betahistine	5638-76-6	MetaADEDB
betamethasone dipropionate	5593-20-4	MetaADEDB
Bimatoprost	155206-00-1	MetaADEDB
Bleomycin	11056-06-7	ADReCS
Bleomycin a2	11116-31-7	SIDER
Bortezomib	179324-69-7	MetaADEDB
Brimonidine	59803-98-4	MetaADEDB
Budesonide	51333-22-3	MetaADEDB
Buprenorphine	52485-79-7	MetaADEDB
Bupropion	34841-39-9	MetaADEDB
Caffeine	58-08-2	MetaADEDB
Calcipotriol	112965-21-6	MetaADEDB
Calcitriol	32222-06-3	MetaADEDB
Calcium	7440-70-2	MetaADEDB
Capecitabine	154361-50-9	ADReCS
Carvedilol	72956-09-3	MetaADEDB
Cefdinir	91832-40-5	MetaADEDB
Cefuroxime	55268-75-2	MetaADEDB
Cefuroxime axetil	64544-07-6	MetaADEDB
Celecoxib	169590-42-5	MetaADEDB
Cephalexin	15686-71-2	MetaADEDB
Cerivastatin	145599-86-6	MetaADEDB
Cetirizine	83881-51-0	ADReCS
Cevimeline	107233-08-9	ADReCS
Chlorhexidine	55-56-1	ADReCS
Chlorhexidine gluconate	18472-51-0	MetaADEDB
Chloroquine	54-05-7	MetaADEDB
Chlorpromazine	50-53-3	MetaADEDB
Ciclopirox	29342-05-0	MetaADEDB
Cinacalcet	226256-56-0	MetaADEDB
Cisapride	81098-60-4	MetaADEDB
Citalopram	59729-33-8	MetaADEDB
Clindamycin	18323-44-9	MetaADEDB
Clobetasol propionate	25122-46-7	MetaADEDB
Colchicine	64-86-8	MetaADEDB
Cortisone	53-06-5	MetaADEDB
Cyclobenzaprine	303-53-7	MetaADEDB
Cyclosporine	59865-13-3	ADReCS
Dapsone	80-08-0	MetaADEDB
Darifenacin	133099-04-4	MetaADEDB
Diazepam	439-14-5	MetaADEDB
Diflunisal	22494-42-4	MetaADEDB
Diltiazem	42399-41-7	ADReCS
diosmin	520-27-4	MetaADEDB
Dolasetron	115956-12-2	MetaADEDB
Donepezil	120014-06-4	ADReCS
Doxercalciferol	54573-75-0	MetaADEDB
Doxycycline	564-25-0	MetaADEDB
duloxetine	136434-34-9	SIDER
Enalapril	75847-73-3	MetaADEDB
Estradiol	50-28-2	MetaADEDB
Etodolac	41340-25-4	MetaADEDB
Famotidine	76824-35-6	MetaADEDB
Fluconazole	86386-73-4	MetaADEDB
Fluocinolone Acetonide	67-73-2	ADReCS
Fluoxetine	54910-89-3	ADReCS
Fluphenazine	69-23-8	MetaADEDB
Flupirtine	56995-20-1	MetaADEDB
Fluticasone Propionate	80474-14-2	MetaADEDB
Fosamprenavir	226700-79-4	MetaADEDB
Fosinopril	98048-97-6	MetaADEDB
Fulvestrant	129453-61-8	MetaADEDB
Gadoteridol	120066-54-8	MetaADEDB
Gadoversetamide	131069-91-5	MetaADEDB
Ganciclovir	82410-32-0	MetaADEDB
Gliclazide	21187-98-4	ADReCS
Glipizide	29094-61-9	MetaADEDB
Granisetron	109889-09-0	MetaADEDB
Hydrochlorothiazide	58-93-5	MetaADEDB
Hydroxychloroquine	118-42-3	MetaADEDB
Hydroxyzine	68-88-2	MetaADEDB
iloprost	78919-13-8	MetaADEDB
Imiquimod	99011-02-6	ADReCS
Infliximab	170277-31-3	PROTECT
Ipratropium bromide	22254-24-6	MetaADEDB
Ketoprofen	22071-15-4	MetaADEDB
ketorolac tromethamine	74103-07-4	MetaADEDB
Labetalol	36894-69-6	MetaADEDB
Lansoprazole	103577-45-3	MetaADEDB
Lenalidomide	191732-72-6	MetaADEDB
Letrozole	112809-51-5	MetaADEDB
Leuprolide	53714-56-0	ADReCS
Leuprolide acetate	74381-53-6	SIDER
Levothyroxine	51-48-9	MetaADEDB
Lithium Carbonate	554-13-2	MetaADEDB
Lorazepam	846-49-1	MetaADEDB
Losartan	114798-26-4	MetaADEDB
Loteprednol	82034-46-6	MetaADEDB
Lubiprostone	136790-76-6	MetaADEDB
Mefloquine	53230-10-7	MetaADEDB
Melphalan	148-82-3	MetaADEDB
Mesalazine	89-57-6	ADReCS
Metaxalone	1665-48-1	MetaADEDB
Methocarbamol	532-03-6	MetaADEDB
methylcobalamin	13422-55-4	MetaADEDB
Methyltestosterone	58-18-4	MetaADEDB
Metolazone	17560-51-9	MetaADEDB
Metronidazole	443-48-1	MetaADEDB
Midodrine	133163-28-7	MetaADEDB
Mitoxantrone	65271-80-9	MetaADEDB
montelukast sodium	151767-02-1	MetaADEDB
Moxifloxacin	151096-09-2	MetaADEDB
Mupirocin	12650-69-0	MetaADEDB
Mycophenolate mofetil	128794-94-5	MetaADEDB
Nabumetone	42924-53-8	MetaADEDB
Naltrexone	16590-41-3	MetaADEDB
Naproxen	22204-53-1	MetaADEDB
Nicardipine	55985-32-5	MetaADEDB
Nilotinib	641571-10-0	ADReCS
Nimesulide	51803-78-2	MetaADEDB
Nitisinone	104206-65-7	PROTECT
Nitrofurantoin	67-20-9	MetaADEDB
Nizatidine	76963-41-2	MetaADEDB
Olanzapine	132539-06-1	MetaADEDB
Ondansetron	99614-02-5	MetaADEDB
opipramol	315-72-0	MetaADEDB
Orphenadrine	83-98-7	MetaADEDB
Oxaprozin	21256-18-8	MetaADEDB
Oxybutynin	5633-20-5	MetaADEDB
Paliperidone	144598-75-4	PROTECT
Pamidronate	40391-99-9	MetaADEDB
Pantoprazole	102625-70-7	MetaADEDB
Paricalcitol	131918-61-1	MetaADEDB
Penicillin v	87-08-1	MetaADEDB
Pergolide	66104-22-1	MetaADEDB
Phenprocoumon	435-97-2	MetaADEDB
Pimecrolimus	137071-32-0	MetaADEDB
Pimozide	2062-78-4	MetaADEDB
Piracetam	7491-74-9	MetaADEDB
Piroxicam	36322-90-4	MetaADEDB
Polyethylene Glycol	25322-68-3	MetaADEDB
Pramipexole	104632-26-0	ADReCS
Pranoprofen	52549-17-4	MetaADEDB
Prochlorperazine	58-38-8	MetaADEDB
Progesterone	57-83-0	MetaADEDB
Propoxyphene	469-62-5	MetaADEDB
Quetiapine	111974-69-7	MetaADEDB
Quinapril	85441-61-8	MetaADEDB
Risedronate	105462-24-6	MetaADEDB
Risperidone	106266-06-2	ADReCS
Rivastigmine	123441-03-2	ADReCS
Rofecoxib	162011-90-7	MetaADEDB
Ropinirole	91374-21-9	ADReCS
Salbutamol	18559-94-9	MetaADEDB
Saquinavir	127779-20-8	MetaADEDB
Sevelamer	152751-57-0	MetaADEDB
Sorafenib	284461-73-0	MetaADEDB
sulfamethoxazole	723-46-6	MetaADEDB
Sulindac	38194-50-2	MetaADEDB
sunitinib	557795-19-4	PROTECT
Tacrine	321-64-2	ADReCS
Tacrolimus	104987-11-3	MetaADEDB
Tamoxifen	10540-29-1	MetaADEDB
Tamsulosin	106133-20-4	MetaADEDB
Tazarotene	118292-40-3	MetaADEDB
Terazosin	63590-64-7	MetaADEDB
Terbinafine	91161-71-6	MetaADEDB
Testosterone	58-22-0	MetaADEDB
Thioridazine	50-52-2	MetaADEDB
Tianeptine	66981-73-5	MetaADEDB
Timolol	26839-75-8	MetaADEDB
Tizanidine	51322-75-9	MetaADEDB
Topiramate	97240-79-4	MetaADEDB
Tramadol	27203-92-5	ADReCS
Tretinoin	302-79-4	MetaADEDB
Triamterene	396-01-0	MetaADEDB
Trifluoperazine	117-89-5	MetaADEDB
Valdecoxib	181695-72-7	MetaADEDB
Valproic Acid	99-66-1	MetaADEDB
Valsartan	137862-53-4	MetaADEDB
Vemurafenib	918504-65-1	ADReCS
Venlafaxine	93413-69-5	MetaADEDB
verapamil	52-53-9	ADReCS
Vinorelbine	71486-22-1	MetaADEDB
Vitamin A	68-26-8	MetaADEDB
Warfarin	81-81-2	MetaADEDB
Zaleplon	151319-34-5	MetaADEDB
Ziprasidone	146939-27-7	MetaADEDB
Zoledronate	118072-93-8	MetaADEDB
Zopiclone	43200-80-2	MetaADEDB

List of proteins causing Hyperkeratosis
Protein Name	Uniprot ID	Source