Drugs Causing Hepatotoxicity: 196
Drug Name	CAS Number	Source
Abacavir	136470-78-5	MetaADEDB
Abiraterone	154229-19-3	PROTECT
Acetaminophen	103-90-2	MetaADEDB
Acetylcysteine	616-91-1	MetaADEDB
Aciclovir	59277-89-3	MetaADEDB
Acitretin	55079-83-9	MetaADEDB
Ambrisentan	177036-94-1	ADReCS
Amiloride Hydrochloride	2016-88-8	MetaADEDB
Aminoglutethimide	125-84-8	ADReCS
Amphotericin B	1397-89-3	MetaADEDB
Amrinone	60719-84-8	ADReCS
Anagrelide	68475-42-3	ADReCS
Apixaban	503612-47-3	MetaADEDB
Asparaginase	9015-68-3	ADReCS
Atenolol	29122-68-7	MetaADEDB
Atomoxetine Hydrochloride	82248-59-7	MetaADEDB
Atovaquone	95233-18-4	MetaADEDB
Azathioprine	446-86-6	ADReCS
Bleomycin	11056-06-7	ADReCS
Bortezomib	179324-69-7	PROTECT
Bosentan	147536-97-8	MetaADEDB
bosutinib	380843-75-4	PROTECT
Budesonide	51333-22-3	MetaADEDB
Busulfan	55-98-1	PROTECT
Caffeine	58-08-2	MetaADEDB
Capecitabine	154361-50-9	ADReCS
Carbimazole	22232-54-8	MetaADEDB
Carfilzomib	868540-17-4	ADReCS
Caspofungin	179463-17-3	ADReCS
Cefaclor	53994-73-3	MetaADEDB
Ceftazidime	78439-06-2	MetaADEDB
Cefuroxime	55268-75-2	MetaADEDB
Chlorambucil	305-03-3	ADReCS
Chloroquine	54-05-7	MetaADEDB
Chlorpromazine	50-53-3	MetaADEDB
Chromium	7440-47-3	MetaADEDB
Cimetidine	51481-61-9	MetaADEDB
Clarithromycin	81103-11-9	MetaADEDB
clavulanic acid	58001-44-8	MetaADEDB
Clofarabine	123318-82-1	ADReCS
Codeine	76-57-3	MetaADEDB
Colistin	1264-72-8	MetaADEDB
Combivir	165456-81-5	MetaADEDB
Cortisone	53-06-5	MetaADEDB
Cyclosporine	59865-13-3	ADReCS
Cyproheptadine	129-03-3	MetaADEDB
Dactinomycin	50-76-0	MetaADEDB
Danazol	17230-88-5	MetaADEDB
Dapsone	80-08-0	MetaADEDB
Darunavir	206361-99-1	ADReCS
Daunorubicin	20830-81-3	MetaADEDB
Demeclocycline	127-33-3	ADReCS
Desflurane	57041-67-5	MetaADEDB
dexamethasone acetate	1177-87-3	MetaADEDB
Dextromethorphan	125-71-3	MetaADEDB
Dicloxacillin	3116-76-5	ADReCS
Didanosine	69655-05-6	ADReCS
Dimenhydrinate	523-87-5	MetaADEDB
dipyrone	68-89-3	MetaADEDB
Dobutamine	34368-04-2	MetaADEDB
Doxycycline	564-25-0	ADReCS
Enfuvirtide	159519-65-0	ADReCS
Enoxaparin	9005-49-6	MetaADEDB
Epoprostenol	35121-78-9	MetaADEDB
Erlotinib	183321-74-6	MetaADEDB
Ethambutol	74-55-5	ADReCS
Ethosuximide	77-67-8	MetaADEDB
Etomidate	33125-97-2	MetaADEDB
Etoposide	33419-42-0	ADReCS
Ezetimibe	163222-33-1	MetaADEDB
Fentanyl	437-38-7	MetaADEDB
Fioricet	122018-95-5	MetaADEDB
Floxacillin	5250-39-5	MetaADEDB
Fludarabine	21679-14-1	MetaADEDB
Flupirtine	56995-20-1	MetaADEDB
Flutamide	13311-84-7	MetaADEDB
Fluvastatin	93957-54-1	MetaADEDB
Fosamprenavir	226700-79-4	MetaADEDB
Ganciclovir	82410-32-0	MetaADEDB
Gefitinib	184475-35-2	ADReCS
Gemcitabine	95058-81-4	ADReCS
Gemtuzumab ozogamicin	220578-59-6	ADReCS
Gentamicin	1403-66-3	MetaADEDB
Glatiramer Acetate	147245-92-9	MetaADEDB
Hydrochlorothiazide	58-93-5	MetaADEDB
Hydroxyurea	127-07-1	ADReCS
Ibuprofen	15687-27-1	MetaADEDB
Ifosfamide	3778-73-2	ADReCS
Imatinib	152459-95-5	ADReCS
imipenem	74431-23-5	MetaADEDB
Ipilimumab	477202-00-9	ADReCS
Isoflurane	26675-46-7	MetaADEDB
Isoniazid	54-85-3	MetaADEDB
Isradipine	75695-93-1	ADReCS
Itraconazole	84625-61-6	ADReCS
Ketamine	6740-88-1	MetaADEDB
Ketoconazole	65277-42-1	MetaADEDB
L-Carnitine	541-15-1	MetaADEDB
Lamivudine	134678-17-4	MetaADEDB
Lansoprazole	103577-45-3	ADReCS
Lapatinib	231277-92-2	PROTECT
Leflunomide	75706-12-6	MetaADEDB
Leuprolide acetate	74381-53-6	MetaADEDB
Lomotil	55840-97-6	MetaADEDB
Lopinavir	192725-17-0	ADReCS
Lorazepam	846-49-1	MetaADEDB
Lormetazepam	848-75-9	MetaADEDB
Maraviroc	376348-65-1	ADReCS
Melphalan	148-82-3	MetaADEDB
Memantine	19982-08-2	MetaADEDB
Mercaptopurine	50-44-2	ADReCS
Metaxalone	1665-48-1	MetaADEDB
Methotrexate	59-05-2	ADReCS
Methylprednisolone	83-43-2	MetaADEDB
Metoclopramide	364-62-5	ADReCS
Minocycline	10118-90-8	MetaADEDB
Minoxidil	38304-91-5	MetaADEDB
Nafcillin	147-52-4	ADReCS
Nalbuphine	20594-83-6	ADReCS
Naproxen	22204-53-1	MetaADEDB
Nevirapine	129618-40-2	ADReCS
Niacin	59-67-6	MetaADEDB
Nilotinib	641571-10-0	ADReCS
Nitrofurantoin	67-20-9	MetaADEDB
Nitrous oxide	10024-97-2	MetaADEDB
Norepinephrine	51-41-2	MetaADEDB
Norethindrone	68-22-4	MetaADEDB
Olsalazine	15722-48-2	ADReCS
opipramol	315-72-0	MetaADEDB
Oxacillin	66-79-5	ADReCS
Oxycodone	76-42-6	ADReCS
Paroxetine	61869-08-7	MetaADEDB
Pazopanib	444731-52-6	ADReCS
Penicillamine	52-67-5	ADReCS
Penicillin v	87-08-1	MetaADEDB
Pentamidine	100-33-4	MetaADEDB
Phenazopyridine	94-78-0	ADReCS
Phenprocoumon	435-97-2	MetaADEDB
Phenytoin	57-41-0	ADReCS
Piritramide	302-41-0	MetaADEDB
Posaconazole	171228-49-2	MetaADEDB
Procarbazine	671-16-9	MetaADEDB
Progesterone	57-83-0	MetaADEDB
Propofol	2078-54-8	MetaADEDB
Propylthiouracil	51-52-5	MetaADEDB
Pyrazinamide	98-96-4	ADReCS
Pyridoxine	65-23-6	MetaADEDB
Quinidine	56-54-2	ADReCS
Regorafenib	755037-03-7	ADReCS
Ribavirin	36791-04-5	PROTECT
Rifampicin	13292-46-1	MetaADEDB
Rifapentine	61379-65-5	ADReCS
Rifaximin	80621-81-4	MetaADEDB
Rilpivirine	500287-72-9	ADReCS
roxithromycin	80214-83-1	MetaADEDB
Saquinavir	127779-20-8	MetaADEDB
scopolamine	51-34-3	MetaADEDB
Sevoflurane	28523-86-6	MetaADEDB
Sirolimus	53123-88-9	PROTECT
Sodium bicarbonate	144-55-8	MetaADEDB
Spironolactone	52-01-7	MetaADEDB
Stavudine	3056-17-5	ADReCS
Streptozocin	18883-66-4	ADReCS
sulfamethoxazole	723-46-6	MetaADEDB
Sulfasalazine	599-79-1	ADReCS
sunitinib	557795-19-4	ADReCS
Tacrolimus	104987-11-3	ADReCS
Tasonermin	94948-59-1	PROTECT
Tazobactam	89786-04-9	MetaADEDB
Telithromycin	191114-48-4	MetaADEDB
Temozolomide	85622-93-1	PROTECT
Tenofovir	147127-20-6	MetaADEDB
Tenofovir disoproxil fumarate	202138-50-9	MetaADEDB
Tetracycline	60-54-8	ADReCS
Thioguanine	154-42-7	MetaADEDB
Thiotepa	52-24-4	MetaADEDB
Tigecycline	220620-09-7	MetaADEDB
Tolbutamide	64-77-7	MetaADEDB
Tolcapone	134308-13-7	MetaADEDB
Topiramate	97240-79-4	MetaADEDB
Torasemide	56211-40-6	MetaADEDB
Toremifene	89778-26-7	ADReCS
Trabectedin	114899-77-3	PROTECT
Tretinoin	302-79-4	MetaADEDB
Troglitazone	97322-87-7	MetaADEDB
Troxipide	30751-05-4	MetaADEDB
Truvada	731772-45-5	MetaADEDB
Ursodeoxycholic acid	128-13-2	MetaADEDB
Valproic Acid	99-66-1	ADReCS
Vancomycin	1404-90-6	MetaADEDB
Vincristine	57-22-7	ADReCS
Vitamin A	68-26-8	MetaADEDB
Voriconazole	137234-62-9	ADReCS
Zaleplon	151319-34-5	PROTECT
Zidovudine	30516-87-1	MetaADEDB
Ziprasidone	146939-27-7	MetaADEDB

List of proteins causing Hepatotoxicity
Protein Name	Uniprot ID	Source