Drugs Causing Hepatic Failure: 390
Drug Name	CAS Number	Source
Abacavir	136470-78-5	ADReCS
Aceclofenac	89796-99-6	MetaADEDB
Acetazolamide	59-66-5	ADReCS
Aciclovir	59277-89-3	MetaADEDB
Acitretin	55079-83-9	MetaADEDB
Actinomycin	1402-38-6	ADReCS
Adalimumab	331731-18-1	PROTECT
Adefovir Dipivoxil	142340-99-6	ADReCS
Agomelatine	138112-76-2	PROTECT
Albendazole	54965-21-8	ADReCS
Alfentanil	71195-58-9	MetaADEDB
Aliskiren	173334-57-1	PROTECT
Allopurinol	315-30-0	ADReCS
Alprazolam	28981-97-7	ADReCS
Ambrisentan	177036-94-1	ADReCS
Ambroxol	18683-91-5	MetaADEDB
Amezinium	41658-78-0	MetaADEDB
Amikacin	37517-28-5	MetaADEDB
Aminophylline	317-34-0	MetaADEDB
Amitriptyline	50-48-6	ADReCS
Amitriptyline Hydrochloride	549-18-8	MetaADEDB
Amlodipine	88150-42-9	MetaADEDB
Amphotericin B	1397-89-3	ADReCS
Amsacrine	51264-14-3	ADReCS
Aprotinin	9087-70-1	ADReCS
Argatroban	74863-84-6	MetaADEDB
Aripiprazole	129722-12-9	PROTECT
Atenolol	29122-68-7	ADReCS
Atorvastatin	134523-00-5	ADReCS
Atovaquone	95233-18-4	ADReCS
Atropine	51-55-8	MetaADEDB
Auranofin	34031-32-8	MetaADEDB
Azacitidine	320-67-2	PROTECT
Azasetron	123040-69-7	MetaADEDB
Azathioprine	446-86-6	ADReCS
Azithromycin	83905-01-5	ADReCS
Balsalazide	80573-04-2	ADReCS
benfluorex	23602-78-0	MetaADEDB
Beractant	108778-82-1	ADReCS
Bexarotene	153559-49-0	ADReCS
Bezafibrate	41859-67-0	MetaADEDB
Bicalutamide	90357-06-5	ADReCS
Biotin	58-85-5	MetaADEDB
Bisacodyl	603-50-9	MetaADEDB
Bisoprolol	66722-44-9	MetaADEDB
Bleomycin	11056-06-7	ADReCS
Bortezomib	179324-69-7	ADReCS
Bosentan	147536-97-8	ADReCS
Bromopride	4093-35-0	MetaADEDB
Budesonide	51333-22-3	MetaADEDB
Buprenorphine	52485-79-7	MetaADEDB
Calcitriol	32222-06-3	MetaADEDB
Candesartan	139481-59-7	ADReCS
Capecitabine	154361-50-9	ADReCS
Carbamazepine	298-46-4	ADReCS
Carbidopa	28860-95-9	MetaADEDB
Carfilzomib	868540-17-4	ADReCS
Caspofungin	179463-17-3	ADReCS
Cefadroxil	66592-87-8	ADReCS
Cefdinir	91832-40-5	ADReCS
Cefepime	88040-23-7	ADReCS
Cefmetazole	56796-20-4	MetaADEDB
Cefotaxime	63527-52-6	MetaADEDB
Cefoxitin	35607-66-0	MetaADEDB
Ceftriaxone	73384-59-5	MetaADEDB
Celecoxib	169590-42-5	ADReCS
Celiprolol	56980-93-9	MetaADEDB
Cetraxate	34675-84-8	MetaADEDB
Chlorhexidine gluconate	18472-51-0	MetaADEDB
Chloroquine	54-05-7	MetaADEDB
Chlorothiazide	58-94-6	MetaADEDB
Chlorpromazine	50-53-3	MetaADEDB
Cilazapril	92077-78-6	MetaADEDB
Ciprofloxacin	85721-33-1	ADReCS
Citalopram	59729-33-8	ADReCS
Cladribine	4291-63-8	PROTECT
Clarithromycin	81103-11-9	ADReCS
Clobetasol propionate	25122-46-7	MetaADEDB
Clopidogrel	113665-84-2	ADReCS
Clotrimazole	23593-75-1	MetaADEDB
Colistin	1264-72-8	MetaADEDB
Cyclosporine	59865-13-3	MetaADEDB
Cyproheptadine	129-03-3	ADReCS
Cyproterone	2098-66-0	ADReCS
Dactinomycin	50-76-0	MetaADEDB
Dantrolene	7261-97-4	ADReCS
Darunavir	206361-99-1	ADReCS
Deferasirox	201530-41-8	ADReCS
deflazacort	14484-47-0	MetaADEDB
Delavirdine	136817-59-9	ADReCS
Demeclocycline	127-33-3	ADReCS
Desflurane	57041-67-5	ADReCS
Dichlorphenamide	120-97-8	ADReCS
Diclofenac	15307-86-5	ADReCS
Didanosine	69655-05-6	ADReCS
Digoxin	20830-75-5	MetaADEDB
dihydrocodeine	125-28-0	MetaADEDB
dimethindene	5636-83-9	MetaADEDB
Diphenhydramine	58-73-1	MetaADEDB
dipyrone	68-89-3	MetaADEDB
Distalgesic	39400-85-6	MetaADEDB
Disulfiram	97-77-8	ADReCS
Dobutamine	34368-04-2	MetaADEDB
Docetaxel	114977-28-5	ADReCS
Dolasetron	115956-12-2	MetaADEDB
Doxorubicin	23214-92-8	ADReCS
Doxycycline	564-25-0	MetaADEDB
duloxetine	136434-34-9	PROTECT
edaravone	89-25-8	MetaADEDB
Efavirenz	154598-52-4	ADReCS
Enalapril	75847-73-3	ADReCS
enalapril maleate	76095-16-4	SIDER
Enalaprilat	76420-72-9	ADReCS
Enflurane	13838-16-9	ADReCS
Enoxaparin	9005-49-6	MetaADEDB
Entacapone	130929-57-6	ADReCS
Entecavir	142217-69-4	ADReCS
epalrestat	82159-09-9	MetaADEDB
Epinephrine	51-43-4	MetaADEDB
Eplerenone	107724-20-9	MetaADEDB
Epoprostenol	35121-78-9	ADReCS
Erlotinib	183321-74-6	ADReCS
Ertapenem	153832-46-3	ADReCS
Erythromycin	114-07-8	MetaADEDB
Escitalopram	128196-01-0	ADReCS
Esmolol	100286-90-6	MetaADEDB
Esomeprazole	119141-88-7	ADReCS
Ethambutol	74-55-5	MetaADEDB
Etodolac	41340-25-4	ADReCS
Etravirine	269055-15-4	ADReCS
Ezetimibe	163222-33-1	MetaADEDB
Febuxostat	144060-53-7	ADReCS
Felodipine	72509-76-3	MetaADEDB
Finasteride	98319-26-7	MetaADEDB
Flavoxate	15301-69-6	MetaADEDB
Flecainide	54143-55-4	ADReCS
Fluconazole	86386-73-4	ADReCS
Fludarabine	21679-14-1	SIDER
Fludrocortisone	127-31-1	ADReCS
Flumazenil	78755-81-4	MetaADEDB
Fluoxetine	54910-89-3	ADReCS
Flupirtine	56995-20-1	MetaADEDB
Flurbiprofen	5104-49-4	ADReCS
Fluvastatin	93957-54-1	ADReCS
Foscarnet	63585-09-1	MetaADEDB
Fosfluconazole	194798-83-9	MetaADEDB
Fosfomycin	23155-02-4	MetaADEDB
Fosinopril	98048-97-6	ADReCS
Fosphenytoin	93390-81-9	MetaADEDB
Fudosteine	13189-98-5	MetaADEDB
Fulvestrant	129453-61-8	PROTECT
Furosemide	54-31-9	MetaADEDB
Gabapentin	60142-96-3	ADReCS
gabexate mesilate	56974-61-9	MetaADEDB
Galactose	10257-28-0	MetaADEDB
Ganciclovir	82410-32-0	ADReCS
Gatifloxacin	112811-59-3	MetaADEDB
Gemcitabine	95058-81-4	ADReCS
Glatiramer Acetate	147245-92-9	MetaADEDB
Gliclazide	21187-98-4	ADReCS
Glimepiride	93479-97-1	ADReCS
glutathione	70-18-8	MetaADEDB
Glyburide	10238-21-8	ADReCS
glycyrrhizin	1405-86-3	MetaADEDB
gold	7440-57-5	MetaADEDB
Haloperidol	52-86-8	MetaADEDB
Hydrochlorothiazide	58-93-5	MetaADEDB
Hydrocortisone	50-23-7	MetaADEDB
Hydromorphone	466-99-9	ADReCS
Hydroxychloroquine	118-42-3	ADReCS
Hydroxyurea	127-07-1	MetaADEDB
Ibuprofen	15687-27-1	ADReCS
Ifosfamide	3778-73-2	ADReCS
Imatinib	152459-95-5	ADReCS
imipenem	74431-23-5	MetaADEDB
Indinavir	150378-17-9	ADReCS
Infliximab	170277-31-3	PROTECT
Interferon Alfa-2a Recombinant	76543-88-9	ADReCS
Interferon beta-1a	145258-61-3	ADReCS
Interferon beta-1b	145155-23-3	ADReCS
Interferon gamma-1b	82115-62-6	ADReCS
Ioxilan	107793-72-6	ADReCS
Ipilimumab	477202-00-9	PROTECT
Ipratropium bromide	22254-24-6	MetaADEDB
Isoflurane	26675-46-7	ADReCS
Isosorbide Mononitrate	16051-77-7	MetaADEDB
Itraconazole	84625-61-6	ADReCS
Ketamine	6740-88-1	MetaADEDB
Ketoprofen	22071-15-4	MetaADEDB
Ketorolac	66635-83-4	ADReCS
ketorolac tromethamine	74103-07-4	MetaADEDB
L-Carnitine	541-15-1	MetaADEDB
Lactulose	4618-18-2	MetaADEDB
Lamivudine	134678-17-4	ADReCS
Lamotrigine	84057-84-1	MetaADEDB
Lansoprazole	103577-45-3	MetaADEDB
Leflunomide	75706-12-6	ADReCS
Lenalidomide	191732-72-6	ADReCS
Leuprolide acetate	74381-53-6	MetaADEDB
Levetiracetam	102767-28-2	ADReCS
Levofloxacin	100986-85-4	ADReCS
Levonorgestrel	797-63-7	ADReCS
Linezolid	165800-03-3	MetaADEDB
Lisinopril	83915-83-7	ADReCS
Magnesium	7439-95-4	MetaADEDB
Maraviroc	376348-65-1	ADReCS
Medroxyprogesterone	520-85-4	ADReCS
Medrysone	2668-66-8	ADReCS
Mefenamic acid	61-68-7	ADReCS
Mefloquine	53230-10-7	ADReCS
Megestrol	3562-63-8	MetaADEDB
melatonin	73-31-4	MetaADEDB
Meloxicam	71125-38-7	ADReCS
Memantine	19982-08-2	ADReCS
mequitazine	29216-28-2	MetaADEDB
Meropenem	119478-56-7	ADReCS
Mesalazine	89-57-6	ADReCS
Mesna	19767-45-4	ADReCS
Methadone	76-99-3	MetaADEDB
Methazolamide	554-57-4	ADReCS
Methocarbamol	532-03-6	MetaADEDB
Methotrexate	59-05-2	ADReCS
Metoclopramide	364-62-5	MetaADEDB
Metolazone	17560-51-9	ADReCS
Metronidazole	443-48-1	MetaADEDB
Micafungin	235114-32-6	ADReCS
Midazolam	59467-70-8	MetaADEDB
Midodrine	133163-28-7	MetaADEDB
Milrinone	78415-72-2	MetaADEDB
Minocycline	10118-90-8	ADReCS
mizoribine	50924-49-7	MetaADEDB
mk-521	CASNA517	SIDER
Modafinil	68693-11-8	MetaADEDB
Morphine	57-27-2	MetaADEDB
mosapride	112885-41-3	MetaADEDB
Moxifloxacin	151096-09-2	ADReCS
Mupirocin	12650-69-0	MetaADEDB
Mycophenolate mofetil	128794-94-5	MetaADEDB
Nabumetone	42924-53-8	ADReCS
Naproxen	22204-53-1	ADReCS
Nebivolol	99200-09-6	MetaADEDB
Nefazodone	83366-66-9	ADReCS
Nevirapine	129618-40-2	ADReCS
Nicotine	54-11-5	MetaADEDB
Nilvadipine	75530-68-6	MetaADEDB
Nimesulide	51803-78-2	MetaADEDB
Nitisinone	104206-65-7	ADReCS
Nitrazepam	146-22-5	MetaADEDB
Nitroglycerin	55-63-0	ADReCS
Norepinephrine	51-41-2	MetaADEDB
Norfloxacin	70458-96-7	ADReCS
Nystatin	1400-61-9	MetaADEDB
Octreotide	83150-76-9	MetaADEDB
Ofloxacin	82419-36-1	ADReCS
Olanzapine	132539-06-1	ADReCS
Olopatadine	113806-05-6	MetaADEDB
Olsalazine	15722-48-2	ADReCS
Omeprazole	73590-58-6	ADReCS
Ondansetron	99614-02-5	ADReCS
opipramol	315-72-0	MetaADEDB
Orlistat	96829-58-2	ADReCS
oseltamivir	204255-11-8	MetaADEDB
Oxacillin	66-79-5	MetaADEDB
Oxaliplatin	61825-94-3	MetaADEDB
Oxaprozin	21256-18-8	ADReCS
Oxazepam	604-75-1	MetaADEDB
Oxybutynin	5633-20-5	MetaADEDB
Oxycodone	76-42-6	MetaADEDB
Pancuronium	15500-66-0	MetaADEDB
Panthenol	16485-10-2	MetaADEDB
Pantoprazole	102625-70-7	ADReCS
Parecoxib	202409-33-4	MetaADEDB
Paroxetine	61869-08-7	ADReCS
Pazopanib	444731-52-6	PROTECT
Peginterferon alfa-2a	198153-51-4	PROTECT
Penicillamine	52-67-5	ADReCS
Penicillin v	87-08-1	MetaADEDB
Pentamidine	100-33-4	MetaADEDB
Pentazocine	359-83-1	MetaADEDB
Perindopril	107133-36-8	ADReCS
Pethidine	57-42-1	MetaADEDB
Phenacetin	62-44-2	MetaADEDB
Phenobarbital	50-06-6	MetaADEDB
Phenprocoumon	435-97-2	MetaADEDB
Phenylephrine	59-42-7	MetaADEDB
Phosphorus	7723-14-0	MetaADEDB
Pioglitazone	111025-46-8	ADReCS
Pirenzepine	28797-61-7	MetaADEDB
Piretanide	55837-27-9	MetaADEDB
Piritramide	302-41-0	MetaADEDB
Piroxicam	36322-90-4	ADReCS
Pitavastatin	147511-69-1	ADReCS
Plaunotol	64218-02-6	MetaADEDB
Polaprezinc	107667-60-7	MetaADEDB
Posaconazole	171228-49-2	ADReCS
Pravastatin	81093-37-0	ADReCS
Prednisolone acetate	52-21-1	MetaADEDB
Primidone	125-33-7	MetaADEDB
Procainamide	51-06-9	ADReCS
Progesterone	57-83-0	ADReCS
Promethazine	60-87-7	MetaADEDB
Propericiazine	2622-26-6	MetaADEDB
Propylthiouracil	51-52-5	ADReCS
Pyrazinamide	98-96-4	MetaADEDB
Pyridoxine	65-23-6	MetaADEDB
quazepam	36735-22-5	MetaADEDB
Quinapril	85441-61-8	ADReCS
Quinidine	56-54-2	MetaADEDB
Raltegravir	518048-05-0	ADReCS
Raltitrexed	112887-68-0	ADReCS
Ramipril	87333-19-5	ADReCS
Ranitidine	66357-35-5	ADReCS
Ribavirin	36791-04-5	ADReCS
Rifaximin	80621-81-4	MetaADEDB
Risperidone	106266-06-2	ADReCS
rocuronium	143558-00-3	MetaADEDB
Rofecoxib	162011-90-7	ADReCS
Rosiglitazone	122320-73-4	ADReCS
Rosuvastatin	287714-41-4	ADReCS
roxithromycin	80214-83-1	MetaADEDB
Salbutamol	18559-94-9	MetaADEDB
Sertraline	79617-96-2	ADReCS
Sevoflurane	28523-86-6	ADReCS
simethicone	8050-81-5	MetaADEDB
Simvastatin	79902-63-9	ADReCS
Sirolimus	53123-88-9	PROTECT
Sitaxentan	210421-64-0	MetaADEDB
Sodium bicarbonate	144-55-8	MetaADEDB
Sorafenib	284461-73-0	MetaADEDB
Sotalol	3930-20-9	MetaADEDB
Spironolactone	52-01-7	MetaADEDB
Stavudine	3056-17-5	ADReCS
Sufentanil	56030-54-7	MetaADEDB
Sulfadiazine	68-35-9	MetaADEDB
Sulfasalazine	599-79-1	ADReCS
Sulindac	38194-50-2	ADReCS
sunitinib	557795-19-4	SIDER
Tacrolimus	104987-11-3	PROTECT
Tamsulosin	106133-20-4	MetaADEDB
Taurine	107-35-7	MetaADEDB
Tazobactam	89786-04-9	MetaADEDB
Telithromycin	191114-48-4	ADReCS
Temocapril	111902-57-9	MetaADEDB
Tenofovir	147127-20-6	MetaADEDB
Tenofovir disoproxil fumarate	202138-50-9	MetaADEDB
Terbinafine	91161-71-6	ADReCS
Terbutaline	23031-25-6	MetaADEDB
Terbutryn	886-50-0	MetaADEDB
Testosterone cypionate	58-20-8	MetaADEDB
Tetracycline	60-54-8	ADReCS
Thiabendazole	148-79-8	ADReCS
Thiamine	59-43-8	MetaADEDB
Thioguanine	154-42-7	MetaADEDB
Thiotepa	52-24-4	PROTECT
Tiapride	51012-32-9	MetaADEDB
Ticlopidine	55142-85-3	ADReCS
Tigecycline	220620-09-7	ADReCS
Tinidazole	19387-91-8	ADReCS
Tipranavir	174484-41-4	ADReCS
Tizanidine	51322-75-9	ADReCS
Tolazamide	1156-19-0	ADReCS
Tolbutamide	64-77-7	MetaADEDB
Tolcapone	134308-13-7	MetaADEDB
Topiramate	97240-79-4	ADReCS
Torasemide	56211-40-6	ADReCS
Tramadol	27203-92-5	ADReCS
Tramazoline	1082-57-1	MetaADEDB
Tranilast	53902-12-8	MetaADEDB
Trastuzumab	180288-69-1	PROTECT
Tremorine	51-73-0	MetaADEDB
Triamcinolone acetonide	76-25-5	MetaADEDB
Triazolam	28911-01-5	ADReCS
Trimethobenzamide	138-56-7	MetaADEDB
Trimethoprim	738-70-5	MetaADEDB
Troglitazone	97322-87-7	MetaADEDB
Trospium	10405-02-4	MetaADEDB
Trovafloxacin	147059-72-1	ADReCS
Truvada	731772-45-5	MetaADEDB
Ursodeoxycholic acid	128-13-2	MetaADEDB
valganciclovir	175865-60-8	MetaADEDB
Valproic Acid	99-66-1	ADReCS
Vancomycin	1404-90-6	MetaADEDB
Vasopressin	11000-17-2	MetaADEDB
Venlafaxine	93413-69-5	ADReCS
Verteporfin	129497-78-5	MetaADEDB
Vincristine	57-22-7	ADReCS
vinflunine	162652-95-1	MetaADEDB
Vinorelbine	71486-22-1	ADReCS
Voriconazole	137234-62-9	ADReCS
Zafirlukast	107753-78-6	ADReCS

List of proteins causing Hepatic Failure
Protein Name	Uniprot ID	Source