| Protein Name: | NADH-cytochrome c reductase isoform (Q9UHQ9) |
|---|---|
| Gene Name: | Not Available |
| Description: | NADH-cytochrome b5 reductase isoform (NAD(P)H:quinone oxidoreductase type 3, polypeptide A2) (GIQT3049) |
| PDB ID: | |
| Protein Family: | |
| Protein Category: |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Zalcitabine | Cardiac Malfunctions | ddC treatment provoked a surprisingly rapid appearance of cardiac malfunctions characterized by significantly decreased activity of respiratory complexes (NADH: cytochrome c oxidoreductase and cytochrome oxidase). [ ADR Type 2 ] | Molecular mechanism of the short-term cardiotoxicity caused by 2',3'-dideoxycytidine (ddC): modulation of reactive oxygen species levels and ADP-ribosylation reactions |
This panel provides information on drug category
| Toxicity | Source |
|---|