| Protein Name: | Granulocyte colony-stimulating factor receptor (Q99062) |
|---|---|
| Gene Name: | CSF3R |
| Description: | Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen) |
| PDB ID: | 1AZ7 |
| Protein Family: | |
| Protein Category: | Membrane Receptors |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Famotidine | Bone Marrow Failure | The interleukin 3-(IL-3) and granulocyte macrophage colony-stimulating factor-(GM-CSF) dependent growth was affected; a combination of growth factors (IL-3@ GM-CSF@ and G-CSF@ the granulocyte colony-stimulating factor) resulted in a less reduced growth@which is compatible with drug-induced bone marrow failure [ ADR Type 5 ] | The growth capacity of hematopoietic progenitor cells in severe neutropenia induced by famotidine |
This panel provides information on drug category
| Toxicity | Source |
|---|