| Protein Name: | DNA gyrase subunit A (P48369) |
|---|---|
| Gene Name: | Not Available |
| Description: | DNA gyrase subunit A (EC 5 99 1 3) |
| PDB ID: | |
| Protein Family: | |
| Protein Category: |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Ciprofloxacin | Increase Morbidity | The gyrA gene mutation is sufficient to confer resistance to nalidixic acid and reduced susceptibility to ciprofloxacin@which can increase morbidity and mortality due to delay in appropriate antibiotic treatment [ ADR Type 3 ] | Reduced susceptibility to ciprofloxacin and gyra gene mutation in North Indian strains of Salmonella enterica serotype Typhi and serotype |
| Ciprofloxacin | Increase Mortality | The gyrA gene mutation is sufficient to confer resistance to nalidixic acid and reduced susceptibility to ciprofloxacin@which can increase morbidity and mortality due to delay in appropriate antibiotic treatment [ ADR Type 3 ] | Reduced susceptibility to ciprofloxacin and gyra gene mutation in North Indian strains of Salmonella enterica serotype Typhi and serotype |
This panel provides information on drug category
| Toxicity | Source |
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