| Protein Name: | Peroxiredoxin-2 (P32119) |
|---|---|
| Gene Name: | PRDX2 |
| Description: | Peroxiredoxin-2 (EC 1 11 1 15) (Thioredoxin peroxidase 1) (Thioredoxin-dependent peroxide reductase 1) (Thiol-specific antioxidant protein) (TSA) (PRP) (Natural killer cell-enhancing factor B) (NKEF-B) |
| PDB ID: | 1QMV |
| Protein Family: | |
| Protein Category: |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Cisplatin | Cell Death | Prx II antisense enhanced cisplatin-induced cell death. [ ADR Type 2 ] | Synergistic effect of peroxiredoxin II antisense on cisplatin-induced cell death |
| Hydrogen Peroxide | Endow Cancer Cells With Resistance | Peroxiredoxin II endow cancer cells with resistance to both H202 and cisplatin and to grant them radioresistance [ ADR Type 2 ] | Synergistic effect of peroxiredoxin II antisense on cisplatin-induced cell death |
This panel provides information on drug category
| Toxicity | Source |
|---|