| Protein Name: | Peroxiredoxin-5 mitochondrial (P30044) |
|---|---|
| Gene Name: | PRDX5 |
| Description: | Peroxiredoxin-5, mitochondrial precursor (EC 111115) (Prx-V) (Peroxisomal antioxidant enzyme) (PLP) (Thioredoxin reductase) (Thioredoxin peroxidase PMP20) (Antioxidant enzyme B166) (AOEB166) (TPx type VI) (Liver tissue 2D-page spot 71B) (Alu corepresso |
| PDB ID: | 1H4O |
| Protein Family: | |
| Protein Category: |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Doxorubicin | Toxic Effects In The Skin | Doxorubicin depletes reductive capacity@ i.e. decreased the activity of thioredoxin reductase in the skin@ as well as the content of reduced glutathione both in the skin and blood plasma.@which leads to toxic effects of doxorubicin in the skin. [ ADR Type 5 ] | Doxorubicin toxicity to the skin: possibility of protection with antioxidants enriched yeast |
This panel provides information on drug category
| Toxicity | Source |
|---|