| Protein Name: | P-selectin (P16109) |
|---|---|
| Gene Name: | SELP |
| Description: | P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen) |
| PDB ID: | 1FSB |
| Protein Family: | |
| Protein Category: | Adhesion |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Indomethacin | Gastropathy | Indomethacin induced gastropathy in CD18@ intercellular adhesion molecule 1@ or P-selectin deficient mice [ ADR Type 3 ] | Indomethacin induced gastropathy in CD18, intercellular adhesion molecule 1, or P-selectin deficient mice Gut |
| Methylprednisolone | Chronic Idiopathic Thrombocytopenic Purpura (Itp) | Soluble P-selectin and platelet count increased (P [ ADR Type 2 ] | Soluble P-selectin, interleukin 6, and thrombopoietin levels in children with acute and chronic idiopathic thrombocytopenic purpura and their relationship with mega-dose methylprednisolone therapy: a pilot study |
This panel provides information on drug category
| Toxicity | Source |
|---|