| Protein Name: | Uracil-DNA glycosylase (P13051) |
|---|---|
| Gene Name: | UNG |
| Description: | Uracil-DNA glycosylase (EC 3 2 2 -) (UDG) |
| PDB ID: | 1AKZ |
| Protein Family: | |
| Protein Category: | Enzyme |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Methotrexate | Genotoxicity | MTX exposure caused malformations but did not modify UNG protein expression or activity@ indicating an inability to increase the removal of MTX-induced genotoxic damage [ ADR Type 3 ] | Expression and activity of the DNA repair enzyme uracil DNA glycosylase during organogenesis in the rat conceptus and following methotrexate exposure in vitro |
This panel provides information on drug category
| Toxicity | Source |
|---|