| Protein Name: | Integrin alpha-M (P11215) |
|---|---|
| Gene Name: | ITGAM |
| Description: | Integrin alpha-M precursor (Cell surface glycoprotein MAC-1 alpha subunit) (CR-3 alpha chain) (Leukocyte adhesion receptor MO1) (Neutrophil adherence receptor) (CD11b antigen) |
| PDB ID: | 1A8X |
| Protein Family: | |
| Protein Category: | Membrane Receptors |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Indomethacin | Experimental Dystonia | Induce barrel rotation in the rat;experimental dystonia.Despite a reduction in ICAM-1 after 24 h@ ICAM-1@ in concert with Mac-1@ contributes to mucosal injury and leukocyte infiltration elicited by indomethacin. [ ADR Type 1 ] | Role of intercellular adhesion molecule 1 in indomethacin-induced ileitis |
This panel provides information on drug category
| Toxicity | Source |
|---|