InAADR

Protein Information

Protein Name: 5-hydroxytryptamine receptor 1A (P08908)
Gene Name: HTR1A
Description:
PDB ID:
Protein Family: PF00001, PS00237
Protein Category: Membrane Receptors

This panel provides drug-protein interaction and their ADRs along with references

Interacting Drugs Toxicity Mechanism Reference
Tamsulosin Asthenia Not Available Large-scale prediction and testing of drug activity on side-effect targets

This panel provides information on drug category

Toxicity Source
Anxiety Involvement of 5-HT1A receptors in animal tests of anxiety and depression: evidence from genetic models
Asthenia Large-scale prediction and testing of drug activity on side-effect targets
Cardiac Failure Congestive Large-scale prediction and testing of drug activity on side-effect targets
Dry Eye Large-scale prediction and testing of drug activity on side-effect targets
Dry Mouth Large-scale prediction and testing of drug activity on side-effect targets
Hypothermia Differential induction of 5-HT1A-mediated responses in vivo by three chemically dissimilar 5-HT1A agonists
Insomnia Large-scale prediction and testing of drug activity on side-effect targets
Major Depressive Disorder Effects of citalopram treatment on hypothermic and hormonal responses to the 5-HT1A receptor agonist buspirone in patients with major depression and therapeutic response
Mood Disorders Cell-specific repressor or enhancer activities of Deaf-1 at a serotonin 1A receptor gene polymorphism
Orthostatic Hypotension Large-scale prediction and testing of drug activity on side-effect targets
Panic Disorder Cell-specific repressor or enhancer activities of Deaf-1 at a serotonin 1A receptor gene polymorphism
Peripheral Coldness Large-scale prediction and testing of drug activity on side-effect targets
Priapism Large-scale prediction and testing of drug activity on side-effect targets
Psychotic Disorder Large-scale prediction and testing of drug activity on side-effect targets
Raynaud Phenomenon Large-scale prediction and testing of drug activity on side-effect targets
Serotonin Syndrome Myo-inositol attenuates the enhancement of the serotonin syndrome by lithium

InAADR: Drug-Protein-ADRs database