| Protein Name: | Plasma kallikrein (P03952) |
|---|---|
| Gene Name: | KLKB1 |
| Description: | Plasma kallikrein precursor (EC 3 4 21 34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain] |
| PDB ID: | 2ANW |
| Protein Family: | |
| Protein Category: | Enzyme |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Indomethacin | Enterocolitis | Rats displayed K-K system activation manifested by a significant decrease in plasma prekallikrein and HK functional levels,which play a role in indomethacin induced enterocolitis in genetically susceptible Lewis rats [ ADR Type 3 ] | Kallikrein-kininogen system activation and bradykinin (B2) receptors in indomethacin induced enterocolitis in genetically susceptible Lewis rats |
This panel provides information on drug category
| Toxicity | Source |
|---|