| Protein Name: | vasodilator prostaglandins (P00059) |
|---|---|
| Gene Name: | Not Available |
| Description: | |
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This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Acetylsalicylic acid | Inflammation | Inhibition of the vasodilator prostaglandins, prostaglandin E2 and prostacyclin, as well as the leukotrienes, may reduce their inflammatory effects in several disease states [ ADR Type 1 ] | Prostaglandins and the mechanism of action of anti-inflammatory drugs |
| Sirolimus | Nephrotoxicity | The target of the FKBP12-rapamycin complex is TOR, a lipid and protein kinase homolog that is likely to be required for T-cell proliferation in response to interleukin-2,which may lead to nephrotoxicity [ ADR Type 5 ] | Molecular mechanisms of immunosuppression by cyclosporine, FK506, and rapamycin |
This panel provides information on drug category
| Toxicity | Source |
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