| Protein Name: | Bile salt export pump (O95342) |
|---|---|
| Gene Name: | ABCB11 |
| Description: | Bile salt export pump (ATP-binding cassette sub-family B member 11) |
| PDB ID: | |
| Protein Family: | |
| Protein Category: | Transporters |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Bosentan | Liver Injury | Bosentan-induced liver injury is mediated, at least in part, by inhibition of Bsep/BSEP-causing intracellular accumulation of cytotoxic bile salts and bile salt induced liver cell damage [ ADR Type 2 ] | The endothelin antaGOnist bosentan inhibits the canalicular bile salt export pump: a potential mechanism for hepatic adverse reactions |
This panel provides information on drug category
| Toxicity | Source |
|---|