| Protein Name: | Thymidine kinase 2 mitochondrial (O00142) |
|---|---|
| Gene Name: | TK2 |
| Description: | Thymidine kinase 2, mitochondrial precursor (EC 27121) (Mt-TK) |
| PDB ID: | |
| Protein Family: | |
| Protein Category: |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Zidovudine | Mitochondrial Damage | The mitochondrial isozyme of thymidine kinase (TK2) plays only a minor part in ZDVMP formation,associated with cytotoxicity, thought to be mediated through mitochondrial damage. [ ADR Type 2 ] | Zidovudine phosphorylation and mitochondrial toxicity in vitro |
This panel provides information on drug category
| Toxicity | Source |
|---|