| Protein Name: | N-glucuronyl transferase (I2CQR6) |
|---|---|
| Gene Name: | EXT2 |
| Description: | |
| PDB ID: | |
| Protein Family: | |
| Protein Category: |
This panel provides drug-protein interaction and their ADRs along with references
| Interacting Drugs | Toxicity | Mechanism | Reference |
|---|---|---|---|
| Cisplatin | Nephrotoxicity | Enhanced lipid peroxidation, oxidized glutathione and N-glucuronyl transferase activity,which leads to cadmium nephrotoxicity was characterized by tubular proximal damage with mitochondrial and lysosomal changes and a widespread vesiculation of tubular cells. [ ADR Type 2 ] | Cisplatin nephrotoxicity in cadmium-pretreated rats Enzymatic, functional and morphological studies |
This panel provides information on drug category
| Toxicity | Source |
|---|---|
| Nephrotoxicity | Cisplatin nephrotoxicity in cadmium-pretreated rats Enzymatic, functional and morphological studies |