| Drug Name: | Pilocarpine (92-13-7) |
|---|---|
| PubChem ID: | 5910 |
| SMILES: | CC[C@H]1[C@H](COC1=O)CC2=CN=CN2C |
| InchiKey: | QCHFTSOMWOSFHM-WPRPVWTQSA-N |
| Therapeutic Category: | Autonomic Agents, Cholinergic Agents, Cholinergic Agonists, Miotics, Muscarinic Agonists, Neurotransmitter Agents, Peripheral Nervous System Agents |
| Molecular Weight (dalton) | : | 208.261 |
| LogP | : | 1.1618 |
| Ring Count | : | 1 |
| Hydrogen Bond Acceptor Count | : | 4 |
| Hydrogen Bond Donor Count | : | 0 |
| Total Polar Surface Area | : | 44.12 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
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This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|---|---|---|
| Seizures | delta-Type opioid receptor (P41143) | Changes in hippocampal circuitry after pilocarpine-induced seizures@which caused a decrease in mu- and delta-opioid receptor immunoreactive (MOR-IR and DOR-IR@ respectively) neurons in the hilus and MOR-IR neurons in the granule cell layer. [ ADR Type 5 ] | Changes in hippocampal circuitry after pilocarpine-induced seizures as revealed by opioid receptor distribution and activation |
| Seizures | Mu-Type opioid receptor (P35372) | Changes in hippocampal circuitry after pilocarpine-induced seizures@which caused a decrease in mu- and delta-opioid receptor immunoreactive (MOR-IR and DOR-IR@ respectively) neurons in the hilus and MOR-IR neurons in the granule cell layer. [ ADR Type 5 ] | Changes in hippocampal circuitry after pilocarpine-induced seizures as revealed by opioid receptor distribution and activation |
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category