| Drug Name: | Crizotinib (877399-52-5) |
|---|---|
| PubChem ID: | 11626560 |
| SMILES: | C[C@H](C1=C(C=CC(=C1Cl)F)Cl)OC2=C(N=CC(=C2)C3=CN(N=C3)C4CCNCC4)N |
| InchiKey: | KTEIFNKAUNYNJU-GFCCVEGCSA-N |
| Therapeutic Category: | Antineoplastic Agents, Enzyme Inhibitors, Protein Kinase Inhibitors |
| Molecular Weight (dalton) | : | 450.345 |
| LogP | : | 5.0377 |
| Ring Count | : | 3 |
| Hydrogen Bond Acceptor Count | : | 6 |
| Hydrogen Bond Donor Count | : | 2 |
| Total Polar Surface Area | : | 77.99 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
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This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
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This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
|---|---|---|
| Grapefruit Juice | Bone Marrow Toxicity | Grapefruit-medication interactions: forbidden fruit or avoidable consequences? |
| Grapefruit Juice | Torsade De Pointes | Grapefruit-medication interactions: forbidden fruit or avoidable consequences? |
This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category