InAADR

Drug Information

Drug Name: Aflibercept (862111-32-8)
PubChem ID: 124081197
SMILES: CC1CS[C@@H](N=C1C(=O)O)[C@@H](C(=O)O)NC(=O)CCC(=O)[C-]2C=CC=C2.[CH-]1[CH-][CH-][CH-][CH-]1.[Ru]
InchiKey: HREUICNNTRSSGZ-YBXLMLQNSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 545.579
LogP: 2.5754
Ring Count: 2
Hydrogen Bond Acceptor Count: 6
Hydrogen Bond Donor Count: 3
Total Polar Surface Area: 133.13

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain ADReCS
Abdominal Pain ADReCS
Abnormal Sensation In Eye PROTECT
Alanine Aminotransferase Increased ADReCS
Anal Fistula PROTECT
Anastomotic Leak PROTECT
Angina Pectoris PROTECT
Anterior Chamber Flare PROTECT
Aphthous Stomatitis PROTECT
Aspartate Aminotransferase Abnormal ADReCS
Aspartate Aminotransferase Increased ADReCS
Asthenia ADReCS
Blood Creatinine Increased ADReCS
Cataract ADReCS
Cataract Cortical PROTECT
Cataract Nuclear PROTECT
Cataract Subcapsular PROTECT
Catheter Site Infection PROTECT
Cerebrovascular Accident PROTECT
Colitis Ischaemic PROTECT
Conjunctival Haemorrhage ADReCS
Conjunctival Hyperaemia ADReCS
Corneal Abrasion PROTECT
Corneal Epithelium Defect PROTECT
Corneal Erosion ADReCS
Corneal Oedema ADReCS
Death PROTECT
Decreased Appetite ADReCS
Deep Vein Thrombosis PROTECT
Dehydration ADReCS
Detachment Of Retinal Pigment Epithelium PROTECT
Diarrhoea ADReCS
Dizziness PROTECT
Dysphonia ADReCS
Dyspnoea ADReCS
Embolism Arterial PROTECT
Embolism Venous PROTECT
Endophthalmitis ADReCS
Enterocutaneous Fistula PROTECT
Enterovesical Fistula PROTECT
Epistaxis ADReCS
Eye Inflammation ADReCS
Eye Pain ADReCS
Eyelid Irritation PROTECT
Eyelid Oedema ADReCS
Fatigue ADReCS
Febrile Neutropenia PROTECT
Female Genital Tract Fistula PROTECT
Fistula PROTECT
Foreign Body Sensation In Eyes ADReCS
Gastrointestinal Haemorrhage PROTECT
Gastrointestinal Perforation PROTECT
Haematuria PROTECT
Haemoptysis PROTECT
Haemorrhage PROTECT
Haemorrhage Intracranial PROTECT
Haemorrhoids ADReCS
Headache ADReCS
Hypersensitivity ADReCS
Hypertension ADReCS
Hypopyon PROTECT
Impaired Healing PROTECT
Infection PROTECT
Injection Site Haemorrhage ADReCS
Injection Site Irritation PROTECT
Injection Site Pain ADReCS
Intestinal Fistula PROTECT
Intracardiac Thrombus PROTECT
Intraocular Pressure Increased ADReCS
Iridocyclitis PROTECT
Iritis PROTECT
Lacrimation Increased ADReCS
Lenticular Opacities PROTECT
Leukopenia ADReCS
Myocardial Infarction PROTECT
Nasopharyngitis PROTECT
Nephrotic Syndrome PROTECT
Neutropenia ADReCS
Neutropenic Infection PROTECT
No Match PROTECT
Ocular Hyperaemia PROTECT
Oropharyngeal Pain ADReCS
Palmar-Plantar Erythrodysaesthesia Syndrome ADReCS
Pneumonia PROTECT
Post Procedural Haemorrhage PROTECT
Posterior Reversible Encephalopathy Syndrome PROTECT
Proctalgia ADReCS
Proteinuria ADReCS
Pulmonary Embolism PROTECT
Pulmonary Haemorrhage PROTECT
Rectal Haemorrhage ADReCS
Retinal Degeneration PROTECT
Retinal Detachment ADReCS
Retinal Pigment Epithelial Tear PROTECT
Retinal Vascular Thrombosis PROTECT
Rhinorrhoea ADReCS
Sepsis PROTECT
Skin Hyperpigmentation ADReCS
Stomatitis ADReCS
Thrombocytopenia ADReCS
Thrombotic Microangiopathy PROTECT
Tooth Infection PROTECT
Toothache PROTECT
Transient Ischaemic Attack PROTECT
Upper Respiratory Tract Infection PROTECT
Urinary Tract Infection ADReCS
Uveitis PROTECT
Vision Blurred ADReCS
Vitreous Detachment ADReCS
Vitreous Floaters ADReCS
Vitreous Haemorrhage PROTECT
Vitritis PROTECT
Weight Decreased ADReCS
Wound Dehiscence PROTECT

InAADR: Drug-Protein-ADRs database