| Drug Name: | Bryostatin 1 (83314-01-6) |
|---|---|
| PubChem ID: | 122361528 |
| SMILES: | CCC/C=C/C=C/C(=O)O[C@H]1C(=CC(=O)OC)C[C@H]2C[C@@H](OC(=O)C[C@@H](C[C@@H]3C[C@@H](C([C@@](O3)(C[C@@H]4C/C(=C/C(=O)OC)/C[C@@H](O4)/C=CC([C@@]1(O2)O)(C)C)O)(C)C)OC(=O)C)O)[C@@H](C)O |
| InchiKey: | MJQUEDHRCUIRLF-FIYURIMHSA-N |
| Therapeutic Category: |
| Molecular Weight (dalton) | : | 905.044 |
| LogP | : | 4.2799 |
| Ring Count | : | 0 |
| Hydrogen Bond Acceptor Count | : | 17 |
| Hydrogen Bond Donor Count | : | 4 |
| Total Polar Surface Area | : | 240.11 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
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This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|---|---|---|
| Apoptosis | TNF receptor-associated factor 1 (Q13077) | Paclitaxel-induced apoptosis of breast cancer cells Expression of the anti-apoptotic tumor necrosis factor receptor associated factor 1 (TRAF1) and defender-against cell death (DAD-1) is regulated by NF-kappaB in certain breast cancer cells [ ADR Type 2 ] | Paclitaxel sensitivity of breast cancer cells with constitutively active NF-kappaB is enhanced by IkappaBalpha super-repressor |
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category
| Toxicity | Source |
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