| Drug Name: | 8-OH-DPAT (78950-78-4) |
|---|---|
| PubChem ID: | 1220 |
| SMILES: | CCCN(CCC)C1CCC2=C(C1)C(=CC=C2)O |
| InchiKey: | ASXGJMSKWNBENU-UHFFFAOYSA-N |
| Therapeutic Category: |
| Molecular Weight (dalton) | : | 247.382 |
| LogP | : | 3.3715 |
| Ring Count | : | 1 |
| Hydrogen Bond Acceptor Count | : | 2 |
| Hydrogen Bond Donor Count | : | 1 |
| Total Polar Surface Area | : | 23.47 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|---|---|---|
| Hyperphagic Syndrome | Neuropeptide Y (P01303) | ENHANCED expression of preproNPY mRNA in the arcuate nucleus in obese Zucker rats during repeated administration of mifepristone suggesting an involvement of NPY in the pathophysiology of the hyperphagic syndrome. [ ADR Type 2 ] | Effects of repeated administration of mifepristone and 8-OH-DPAT on expression of preproneuropeptide Y mRNA in the arcuate nucleus of obese Zucker rats |
| Obesity | Neuropeptide Y (P01303) | ENHANCED expression of preproNPY mRNA in the arcuate nucleus in obese Zucker rats during repeated administration of mifepristone suggesting genetically determined obesity in Zucker rats [ ADR Type 2 ] | Effects of repeated administration of mifepristone and 8-OH-DPAT on expression of preproneuropeptide Y mRNA in the arcuate nucleus of obese Zucker rats |
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
|---|
This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category
| Toxicity | Source |
|---|