| Drug Name: | Nilotinib (641571-10-0) |
|---|---|
| PubChem ID: | 644241 |
| SMILES: | CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CC=C5 |
| InchiKey: | HHZIURLSWUIHRB-UHFFFAOYSA-N |
| Therapeutic Category: |
| Molecular Weight (dalton) | : | 529.526 |
| LogP | : | 6.35584 |
| Ring Count | : | 5 |
| Hydrogen Bond Acceptor Count | : | 7 |
| Hydrogen Bond Donor Count | : | 2 |
| Total Polar Surface Area | : | 97.62 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
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This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
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This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
|---|---|---|
| Grapefruit Juice | Bone Marrow Toxicity | Grapefruit-medication interactions: forbidden fruit or avoidable consequences? |
| Grapefruit Juice | Torsade De Pointes | Grapefruit-medication interactions: forbidden fruit or avoidable consequences? |
This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category