| Drug Name: | Aminopyrine (58-15-1) |
|---|---|
| PubChem ID: | 6009 |
| SMILES: | CC1=C(C(=O)N(N1C)C2=CC=CC=C2)N(C)C |
| InchiKey: | RMMXTBMQSGEXHJ-UHFFFAOYSA-N |
| Therapeutic Category: |
| Molecular Weight (dalton) | : | 231.299 |
| LogP | : | 1.55042 |
| Ring Count | : | 2 |
| Hydrogen Bond Acceptor Count | : | 4 |
| Hydrogen Bond Donor Count | : | 0 |
| Total Polar Surface Area | : | 30.17 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Methotrexate (59-05-2) | Pancytopenia | Synergistic | Methotrexate is largely cleared unchanged from the body by renal excretion. The NSAIDs as a group inhibit the synthesis of the prostaglandins (PGE2) resulting in a fall in renal perfusion, which could lead to a rise in serum methotrexate levels | Megaloblastic pancytopenia in a female patient with rheumatoid arthritis given methotrexate and amidopyrine simultaneously |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category