| Drug Name: | Domperidone (57808-66-9) |
|---|---|
| PubChem ID: | 3151 |
| SMILES: | C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O |
| InchiKey: | FGXWKSZFVQUSTL-UHFFFAOYSA-N |
| Therapeutic Category: | Antiemetics, Autonomic Agents, Central Nervous System Agents, Dopamine Agents, Dopamine Antagonists, Gastrointestinal Agents, Neurotransmitter Agents, Peripheral Nervous System Agents |
| Molecular Weight (dalton) | : | 425.92 |
| LogP | : | 3.3532 |
| Ring Count | : | 4 |
| Hydrogen Bond Acceptor Count | : | 5 |
| Hydrogen Bond Donor Count | : | 2 |
| Total Polar Surface Area | : | 78.82 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|---|---|---|
| Cardiac Arrhythmias | Potassium voltage-gated channel subfamily H member 2 (Q12809) | Role of systems pharmacology in understanding drug adverse events | |
| Somnolence | Neuropeptide S receptor (Q6W5P4) | Not Available | Large-scale prediction and testing of drug activity on side-effect targets |
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
|---|---|---|
| Grapefruit Juice | Torsade De Pointes | Grapefruit-medication interactions: forbidden fruit or avoidable consequences? |
This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category