| Drug Name: | Curcumin (458-37-7) |
|---|---|
| PubChem ID: | 969516 |
| SMILES: | COC1=C(C=CC(=C1)/C=C/C(=O)CC(=O)/C=C/C2=CC(=C(C=C2)O)OC)O |
| InchiKey: | VFLDPWHFBUODDF-FCXRPNKRSA-N |
| Therapeutic Category: | Analgesics, Anti-Inflammatory Agents, Antineoplastic Agents, Antirheumatic Agents, Coloring Agents, Enzyme Inhibitors, Peripheral Nervous System Agents, Sensory System Agents |
| Molecular Weight (dalton) | : | 368.385 |
| LogP | : | 3.3699 |
| Ring Count | : | 2 |
| Hydrogen Bond Acceptor Count | : | 6 |
| Hydrogen Bond Donor Count | : | 2 |
| Total Polar Surface Area | : | 93.06 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|---|---|---|
| Apoptosis | Transcription factor AP-1 (P05412) | Pharmacological inhibition of AP1 activity by diferuloylmethane lead to induction of apoptotic cell death and DNA damage [ ADR Type 2 ] | Evidence that the apoptotic actions of etoposide are independent of c-Jun/activating protein-1-mediated transregulation |
| Dna Damage | Transcription factor AP-1 (P05412) | Pharmacological inhibition of AP1 activity by diferuloylmethane lead to induction of apoptotic cell death and DNA damage [ ADR Type 2 ] | Evidence that the apoptotic actions of etoposide are independent of c-Jun/activating protein-1-mediated transregulation |
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
|---|
This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category