| Drug Name: | Chelerythrine chloride (3895-92-9) |
|---|---|
| PubChem ID: | 72311 |
| SMILES: | C[N+]1=C2C(=C3C=CC(=C(C3=C1)OC)OC)C=CC4=CC5=C(C=C42)OCO5.[Cl-] |
| InchiKey: | WEEFNMFMNMASJY-UHFFFAOYSA-M |
| Therapeutic Category: |
| Molecular Weight (dalton) | : | 383.831 |
| LogP | : | 0.7206 |
| Ring Count | : | 4 |
| Hydrogen Bond Acceptor Count | : | 4 |
| Hydrogen Bond Donor Count | : | 0 |
| Total Polar Surface Area | : | 40.8 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
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This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|---|---|---|
| Tumor Cell Toxicity And Growth Delay | wild-type p53 (P04637) | In vitro and in vivo activity of protein kinase C inhibitor chelerythrine chloride induces tumor cell toxicity and growth delay in vivo p53-deficient SQ-20B HNSCC cells in vivo. [ ADR Type 2 ] | In vitro and in vivo activity of protein kinase C inhibitor chelerythrine chloride induces tumor cell toxicity and growth delay in vivo |
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category
| Toxicity | Source |
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