| Drug Name: | Ephedrine (299-42-3) |
|---|---|
| PubChem ID: | 9294 |
| SMILES: | C[C@@H]([C@@H](C1=CC=CC=C1)O)NC |
| InchiKey: | KWGRBVOPPLSCSI-WPRPVWTQSA-N |
| Therapeutic Category: | Adrenergic Agents, Autonomic Agents, Cardiovascular Agents, Central Nervous System Agents, Central Nervous System Stimulants, Neurotransmitter Agents, Peripheral Nervous System Agents, Sympathomimetics, Vasoconstrictor Agents |
| Molecular Weight (dalton) | : | 165.236 |
| LogP | : | 1.3279 |
| Ring Count | : | 1 |
| Hydrogen Bond Acceptor Count | : | 2 |
| Hydrogen Bond Donor Count | : | 2 |
| Total Polar Surface Area | : | 32.26 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Entacapone (130929-57-6) | Hypertension | Synergistic | COMT inhibitors may inhibit the normal metabolism of ephedrine | Severe vascular toxicity associated with vinblastine, bleomycin, and cisplatin chemotherapy |
| Selegiline (14611-51-9) | Hypertensive Crisis | Synergistic | Ephedrine is an indirectly-acting sympathomimetic that causes increased release of noradrenaline; selegiline has some MAO-A ininhibitory activity and may therefore inhibit noradrenaline metabolism | Pseudo-phaeochromocytoma after multiple drug interactions involving the selective monoamine oxidase inhibitor selegiline |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
|---|
This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category