| Drug Name: | Lapatinib (231277-92-2) |
|---|---|
| PubChem ID: | 208908 |
| SMILES: | CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl |
| InchiKey: | BCFGMOOMADDAQU-UHFFFAOYSA-N |
| Therapeutic Category: | Antineoplastic Agents, Enzyme Inhibitors, Protein Kinase Inhibitors |
| Molecular Weight (dalton) | : | 581.069 |
| LogP | : | 6.1391 |
| Ring Count | : | 5 |
| Hydrogen Bond Acceptor Count | : | 8 |
| Hydrogen Bond Donor Count | : | 2 |
| Total Polar Surface Area | : | 106.35 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
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This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
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This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
|---|---|---|
| Grapefruit Juice | Bone Marrow Toxicity | Grapefruit-medication interactions: forbidden fruit or avoidable consequences? |
| Grapefruit Juice | Torsade De Pointes | Grapefruit-medication interactions: forbidden fruit or avoidable consequences? |
This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category