| Drug Name: | Lincomycin (154-21-2) |
|---|---|
| PubChem ID: | 3000540 |
| SMILES: | CCC[C@@H]1C[C@H](N(C1)C)C(=O)N[C@@H]([C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)SC)O)O)O)[C@@H](C)O |
| InchiKey: | OJMMVQQUTAEWLP-KIDUDLJLSA-N |
| Therapeutic Category: | Anti-Bacterial Agents, Anti-Infective Agents, Enzyme Inhibitors, Protein Synthesis Inhibitors |
| Molecular Weight (dalton) | : | 406.545 |
| LogP | : | -0.857 |
| Ring Count | : | 0 |
| Hydrogen Bond Acceptor Count | : | 8 |
| Hydrogen Bond Donor Count | : | 5 |
| Total Polar Surface Area | : | 122.49 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Kaolin (1332-58-7) | Diarrhoea | Antagonistic | It seems probable that the lincomycin becomes adsorbed onto the kaolin, thereby reducing its bioavailability. The kaolin also coats the lining of the gut and acts as a physical barrier to absorption | Pharmacokinetic evaluation of a drug interaction between kaolin--pectin and clindamycin |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
|---|
This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category