| Drug Name: | Rizatriptan (145202-66-0) |
|---|---|
| PubChem ID: | 5078 |
| SMILES: | CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3 |
| InchiKey: | ULFRLSNUDGIQQP-UHFFFAOYSA-N |
| Therapeutic Category: | Neurotransmitter Agents, Serotonin Agents, Serotonin Receptor Agonists |
| Molecular Weight (dalton) | : | 269.352 |
| LogP | : | 1.9118 |
| Ring Count | : | 3 |
| Hydrogen Bond Acceptor Count | : | 4 |
| Hydrogen Bond Donor Count | : | 1 |
| Total Polar Surface Area | : | 49.74 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| moclobemide (71320-77-9) | Dizziness | Synergistic | MAO-A is the principal enzyme concerned with the metabolism of rizatriptan. Moclobemide inhibits this enzyme and therefore raises rizatriptan levels | The effects of moclobemide on the pharmacokinetics of the 5-HT1B/1D agonist rizatriptan in healthy volunteers |
| moclobemide (71320-77-9) | Nausea | Synergistic | MAO-A is the principal enzyme concerned with the metabolism of rizatriptan. Moclobemide inhibits this enzyme and therefore raises rizatriptan levels | The effects of moclobemide on the pharmacokinetics of the 5-HT1B/1D agonist rizatriptan in healthy volunteers |
| moclobemide (71320-77-9) | Somnolence | Synergistic | MAO-A is the principal enzyme concerned with the metabolism of rizatriptan. Moclobemide inhibits this enzyme and therefore raises rizatriptan levels | The effects of moclobemide on the pharmacokinetics of the 5-HT1B/1D agonist rizatriptan in healthy volunteers |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
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This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category