| Drug Name: | Pantoprazole (102625-70-7) |
|---|---|
| PubChem ID: | 4679 |
| SMILES: | COC1=C(C(=NC=C1)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC(F)F)OC |
| InchiKey: | IQPSEEYGBUAQFF-UHFFFAOYSA-N |
| Therapeutic Category: | Anti-Ulcer Agents, Enzyme Inhibitors, Gastrointestinal Agents, Proton Pump Inhibitors |
| Molecular Weight (dalton) | : | 383.376 |
| LogP | : | 2.8843 |
| Ring Count | : | 3 |
| Hydrogen Bond Acceptor Count | : | 6 |
| Hydrogen Bond Donor Count | : | 1 |
| Total Polar Surface Area | : | 86.33 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Methotrexate (59-05-2) | Myalgia | Synergistic | Proton pump inhibitors may affect renal, and possibly hepatic, clearance of methotrexate by inhibition of methotrexate transporter proteins | Drug points: Severe myalgia from an interaction between treatments with pantoprazole and methotrexate |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category